• Created a spatial transcriptomics alignment method competitive with the current best alignment methods• Designed network analysis-based methods to computationally capture and evaluate features of tissue• Implemented post-ML embedding analysis methods on spatial transcriptomics for tissue pattern discovery and comparison• Performed deep learning model optimization to improve tissue alignment outputs based on custom evaluation metrics• Presented at the NSF Cell Manufacturing Technologies Summer 2024 REU Research Symposium

• Engineered self-inserting full-pass transmembrane proteins in synthetic cells• Performed chemical ligation (Click, native chemical ligation) to create chimeric functionalized proteins• Cloned plasmids, expressed and purified engineered proteins in bacteria with post-expression chemical functionalization• Created and imaged giant unilamellar vesicles with centrifugation techniques and varying lipid compositions• Presented at the 2023 (finalist) and 2024 UT BME Undergraduate Research Symposium

• Restructured TEWH leadership and organized officer responsibilities and interdependencies via meetings, email, and Slack• Facilitated communication with the engineering department and other student organizations for operational collaboration• Oversaw event planning (general meetings, socials) to increase membership and attendance

• Engineered a novel drug delivery system using exosome-liposome hybrids across the blood-brain barrier• Designed experimental assays (FRET, encapsulation, barrier transport) to determine efficacy of hybrid delivery• Synthesized liposomes of varying membrane compositions through co-extrusion for hybrid formation• Conducted a literature review on exosome transport across the blood-brain barrier, focusing on CNS disease applications • Cultured and passaged mesenchymal stem cells for exosome isolation• Presented at the 2023 UT CNS Undergraduate Research Forumhttps://texasewh.org/projects/2021/mscexosome/

• Coordinated with organizational officers, project managers, club members, and university staff to fund TEWH operations• Oversaw engineering project timelines and supervised progress on the design process and hardware purchases• Budgeted annual funds for organizational operations

• Developed lesson plans and supplemental materials for teachers and performed quality control on existing courses• Coordinated communication between teaching volunteers, students, parents, and upper-level Codeucate managers• Taught 80+ hours of Python and Java to children ages five to 15https://wecodeucate.org/about-us