Antonio De La Vega De León Email & Phone Number

Seville, Andalusia, Spain

Seville, Andalusia, Spain

Seville, Andalusia, Spain

Sheffield, United Kingdom

Sheffield, United Kingdom

I'm a Marie Curie Fellow associated with the European Project D3i4AD (Diagnostic and Drug Discovery Initiative for Alzheimer's Disease). I develop novel tool compounds to understand the effect of oligomeric forms of amyloid beta on the prion protein and its downstream effects that are thought to lead to synaptotoxic effects. Additionally, I apply machine learning methods such as deep learning to aid in phenotypic screening campaigns.

My research interests are the use of visualizations and method development for structure-activity and structure-property analysis, specifically in the area of compound optimization. Compound optimization is a multi-parametric process and the methods I developed allow medicinal chemists to better understand the relatioships inside the data sets they work on, in order to help in the development of new analogs or novel chemical series.

Bonn Area, Germany

I performed my Master's Thesis under Jurgen Bajorath, where I created a visualization to explore SAR relationships in multi-target data sets, such as kinase profiling data sets.

Madrid Area, Spain

I helped start the analysis of two sequenced bacterial strains. I analyzed the contigs we received and started the assembly.

Madrid Area, Spain

I did molecular genetics work (DNA extraction, PCR, Gel electrophoresis,...) in a genetics diagnostics laboratory.

Master Of Science (M.Sc.), Life Science Informatics

I attended the Life Science Informatics Masters Degree. In this master both bioinformatics and cheminformatics were tought, along.

Bachelor'S Degree, Biology, General

I obtained a Biology degree in the UCM. It was a five year degree, and the last two I specialized on Genetics.