Multi-Omics analysis of Amniotic Fluid (AF) derived cells

Project tilte: "Generation of a single cell atlas of the amniotic fluid and annotation of the cellular identities present within amniotic fluid derived organoid across gestation and in presence of Congenital Diaphragmatic Hernia"I completed an internship at the UCL/Great Ormond Street Institute of Child Health (ICH) Research Facility, based at the Zayed Centre for Research into Rare Disease in Children. Working in the Stem Cells and Regenerative Medicine laboratory led by Paolo De Coppi, Consultant Pediatric Surgeon, and under the guidance of Dr. Mattia Gerli, UCL Lecturer, my research focused on bioinformatic analysis of the cellular composition of amniotic fluid (AF) and its variation in the context of congenital diseases. Additionally, I explored cellular signatures in AF-derived organoids under both healthy and diseased conditions.