Alessia Pancaro Email & Phone Number

Development of biomimetic responsive nanocarriers for inhalable drug delivery in lung cancer

IP valorisation; market study

Belgium

Nanoplasmonic sensing platform for lectin detection.I worked on the development of gold nanorods conjugated with synthetic glycopolymers as a diagnostic biosensing platform for the detection of lectin biomarkers in liquid biopsies. This in vitro assay was tested in human donors serum samples.

Milan, Lombardy, Italy

I studied the binding properties between lectins and glycopolymers using surface plasmon resonance (SPR) technology.

United Kingdom

I synthesized a panel of polymers via photo-initiated reversible addition-fragmentation chain transfer (RAFT) polymerization. I characterized and coupled them to carbohydrate ligands. I functionalized plasmonic nanoparticles and studied the effect of the coating chemistry in different biological matrices. I gained experience in a range of synthetic and analytical chemistry techniques, and the materials developed have become a valuable asset for the further development of the biosensor platform.

Belgium

Subject: Development of green extraction methodologies for the simultaneous valorisation of proteins/carotenoids/ polyphenols from mango by-products Food waste valorisation: - I got acquainted with the extraction and valorisation of food by-products. - I have investigated several protocols to extract products from tropical fruits. - I got worked on supercritical fluid extraction (SFE) of polyphenols and carotenoids. - I used various analytical methodologies (LC-based:… Show more Subject: Development of green extraction methodologies for the simultaneous valorisation of proteins/carotenoids/ polyphenols from mango by-products Food waste valorisation: - I got acquainted with the extraction and valorisation of food by-products. - I have investigated several protocols to extract products from tropical fruits. - I got worked on supercritical fluid extraction (SFE) of polyphenols and carotenoids. - I used various analytical methodologies (LC-based: HPAEC-PAD; UHPLC-MS; RP-HPLC) to characterise the products. - I got acquainted with protein product purity issues and protein product valorisation. - I worked according the Good Quality Control Laboratory Practice (GQCLP).- I processed and presented my results. Show less

Thesis: Chemically modified denatured lysozyme: a new tool to solubilize carbon nanotubesIntegrating nanomaterials with biological systems –e.g. using “biosurfactants” – to form hybrid functional assemblies is an innovative research area for the development of new biomedical and electronic devices, synthetic scaffolds able to promote the adhesion and growth of eukaryotic cells and water treatment processes. During my internship I set up the optimal experimental conditions for the… Show more Thesis: Chemically modified denatured lysozyme: a new tool to solubilize carbon nanotubesIntegrating nanomaterials with biological systems –e.g. using “biosurfactants” – to form hybrid functional assemblies is an innovative research area for the development of new biomedical and electronic devices, synthetic scaffolds able to promote the adhesion and growth of eukaryotic cells and water treatment processes. During my internship I set up the optimal experimental conditions for the solubilization and functionalization of multi-walled carbon nanotubes (MWNTs) using a chemically modified denatured lysozyme. Furthermore, I evaluated MWNTs biocompatibility with cell culture, prepared synthetic scaffolds for eukaryotic cells and analyzed prokaryotes flocculation with microscope. Show less

Thesis: Recombinant expression of MtFAE1 in Saccharomyces cerevisiaeI took part in the project OPTIBIOCAT "Optimized esterase biocatalysts for cost-effective industrial production” that focuses on the development of novel enzymes for the sustainable and cost-effective production of compounds used in the cosmetic industry. I performed my internship extracting the cDNA from an ascomycete and optimizing the codon usage for Saccharomyces cerevisiae. I designed an expression vector with… Show more Thesis: Recombinant expression of MtFAE1 in Saccharomyces cerevisiaeI took part in the project OPTIBIOCAT "Optimized esterase biocatalysts for cost-effective industrial production” that focuses on the development of novel enzymes for the sustainable and cost-effective production of compounds used in the cosmetic industry. I performed my internship extracting the cDNA from an ascomycete and optimizing the codon usage for Saccharomyces cerevisiae. I designed an expression vector with the optimized cDNA and transfected S. cerevisiae studying the enzyme activity. Show less

Phd, Biomedical Sciences

M.Sc In Molecular And Industrial Biotechnology, Summa Cum Laude (110/110 E Lode)

I decided to continue my studies with a Master in Industrial Biotechnology where I acquired a more in-depth knowledge in bionanomaterials.

Bachelor'S Degree, Biomolecular And Industrial Biotechnology, Summa Cum Laude (110/110 E Lode)

In this course I studied different biotechnology field, from bionanomaterials to food science, biofuels to bioremediation, circular.

Classical And Ancient Studies

I studied mainly humanistic subjects such as Latin and ancient Greek, Literature (Greek, Roman and modern), history and philosophy..

English Language, Intermediate

Summer english language study program

English Language And Literature/Letters

Summer international youth program