Alexander Olson Email & Phone Number

San Carlos, California, United States

San Carlos, California, Us

Boston, Massachusetts, Us

Worked with the lab to develop lab execution protocols and implement the UI and UX required by those protocols.Helped migrate LIMS between tech stacks.Designed NGS extension to LIMS.

Emeryville, Ca, Us

Managed a team of 2 Software Engineers that:Maintained rigorous code quality standards.Continuously deployed well-tested builds for internal use.Designed and implemented a serverless AWS platform for internal development.Responded to changing internal requirements regarding the development of Antibody Discovery Products.Designed and implemented new bioinformatics tools for both internal and external users.

Emeryville, Ca, Us

Managed one bioinformaticianMoved pipelines from a local server product to a cloud productExpanded antibody discovery platform to multiple speciesImproved runtime of software while increasing both recall and precision

Emeryville, Ca, Us

Bioinformatic lead on Opto Plasma B Discovery softwareDeveloped a novel algorithm for rapidly assembling antibodies from in-house lab protocolDeveloped visualization tools to explore the results of the antibody discovery workflow. Combining measured assay values with the sequence of each antibody.Worked with legal team to secure patents relevant to the antibody discovery softwareBioinformatics lead for developing a customer-facing tool for OptoSeq 3' single-cell RNA analysis.Responsible for designing and executing DVT for scRNA and Antibody Discovery products.Interfaced with legal team to develop strategy for using GPL code in pipeline.Developed R scripts for RNASeq analysis with robust error reporting to integrate with the software team.

San Jose, California, Us

Worked on Firefly productDeveloped contamination metrics

Austin, Texas, Us

Bioinformatics lead for Signatera RUO pharmaceutical collaborations with AstraZeneca, MedImmune, and Spectrum.Managed the Signatera RUO LIMS environment.Collaborated with Signatera team to determine if external collaborator requests could be meet with existing LIMS infrastructure or required modification.Responsible for processing and QCing all RUO plasma samples generated by the Lab.Developed algorithm improvements to Signatera product while maintaining backwards compatibility.Removed bottle-necks and improved turn around time for Signatera.

Austin, Texas, Us

Worked with bioinformatics, lab, and engineering teams to design LIMS database for Signatera RUOproduction environment.Moved Signatera RUO pipelines to cloud setting.Completely automated Signatera RUO pipelines and LIMS interactions.Regularly modified LIMS database and Signatera RUO pipelines to accommodate custom requests from pharaceutical and academic collaborations.Introduced Git Flow, versioning, unit testing, and other software practices to the bioinformatics team.Developed custom alignment and QC program for Signatera product.Modified open source tools to improve performance for our experimental setup.Improved primer pool design algorithms.Stabilized and documented Primer Design and Plasma Sequencing Pipelines for Signatera productionenvironment.Developed sequencing metrics for Panorama to resolve Illumina reagent issue.

Davis, California, Us

Developed and executed an independent research project on the global prevalence of alternative splicing.Researched and developed statistical methods for analyzing alternative splicing.Developed a program for analyzing deferentially expressed alternative splicing in an organism from RNASeq data. Teaching Assistant – SAS 070A (Genetic Engineering in Medicine, Agriculture, and Law)Facilitated a two hour discussion section each week for a group of approximately 10 students.Prepared a PowerPoint presentation for each discussion to aid the flow of the conversation.Graded all classwork and helped administer and grade the oral midterm and final.Chaperoned students on 3 day trip to UCLA while the professor stayed in Davis.

Davis, California, Us

Researched and tested performance of existing DNA alignment and differential gene expression software.Developed protocols for collecting and analyzing gene and microRNA expression.Automated computational analysis to increase lab efficiency.

Davis, California, Us

Cleaned and washed glassware to be used in biological experiments including reactions involving RNA.Prepared media for growing plant rescues.Maintained a population of Arabidopsis including several mutant lines in controlled environment chambers.Maintained a population of Soybean in a greenhouse.

Moffett Field, California, Us

Worked as an intern to help set up lab.