Alex Snow Email and Phone Number

I am in my final year of postdoctoral research based in the Muench Lab, at the Astbury Biostructure Laboratory, University of Leeds. Here, I have been able to structurally and biophysically characterise an oncogenic variant of a receptor tyrosine kinase. This protein has been notoriously difficult-to-express in a functional form through traditional expression systems, so I adopted and optimised a novel cell-free system, which has resulted in the submission of a publication, with a view to progress to further structural studies. This cell-free technology has the potential to bypass many of the issues preventing similar intractable targets from being studied, and is something I aim to explore comprehensively in future positions.I completed my PhD in Chemistry at the University of York, under the supervision of Professor Gideon Davies of the York Structural Biology Laboratory. Here, I elucidated the functions of and solved structures for many of the enzymes involved in sulfoquinovose catabolism. Before this, I completed a Masters degree in structural molecular biology at Imperial College London.Over the course of these projects, I have demonstrated a proven capacity to devise and execute competitive research, and to develop long-term collaborations both within academia and with industrial partners. Additionally, I have gained significant experience supervising students whilst driving my own research, which has resulted in many of them pursuing PhD projects and becoming independent scientists.I have been able to hone this experience whilst working at state-of-the-art structural biology facilities across the UK, and upon completion of my post-doc, I intend to pursue a research fellowship at a similarly well-equipped institute.