Andrew Fowler Email & Phone Number

Aliso Viejo, California, United States

• Perform blood-based pharmacological assays to track cancer patient drug responses, from end-to-end (sample handling and storage, running various assays, and collection and analysis of results). • Responsible for adhering to Standard Operating Procedures (SOP) in compliance with Good Laboratory Practices (GLP).• Oversee and uphold laboratory inventory, including the acquisition, monitoring, and organization of laboratory supplies and equipment, as well as identifying and recommending… Show more • Perform blood-based pharmacological assays to track cancer patient drug responses, from end-to-end (sample handling and storage, running various assays, and collection and analysis of results). • Responsible for adhering to Standard Operating Procedures (SOP) in compliance with Good Laboratory Practices (GLP).• Oversee and uphold laboratory inventory, including the acquisition, monitoring, and organization of laboratory supplies and equipment, as well as identifying and recommending new products for lab approval.• Gaining comprehensive knowledge of the analysis for all assays performed in the laboratory.• Suggest innovative ideas regularly that lead to positive improvements in laboratory workflow and efficiency. Show less

Carried out research under the mentorship of Dr. Vasanthy Narayanaswami investigating the role of two isoforms of apolipoprotein E (ApoE), ApoE2 and ApoE4, in cardiovascular and Alzheimer’s disease (AD).• Expressed, purified, and characterized the activity of wild-type (WT) ApoE2 as well as various mutants and chimeric fusions of ApoE2 and compared their activities.• Findings revealed that ApoE2 is critical to protection from oxidative stress that occurs during diseases like AD.

Carried out research under the mentorship of Dr. Paul Weers investigating the role of Apolipoprotein A1 (ApoA1) in lipid transport and the innate immunity.• Expressed, purified, and characterized the activity of wild-type (WT) ApoA1 as well as ApoA1 lysine-to- glutamine mutants. Performed comprehensive structure-function analysis for WT and mutant proteins.• Mutagenesis coupled with structure-function analysis revealed the essentiality of two key residues that are responsible… Show more Carried out research under the mentorship of Dr. Paul Weers investigating the role of Apolipoprotein A1 (ApoA1) in lipid transport and the innate immunity.• Expressed, purified, and characterized the activity of wild-type (WT) ApoA1 as well as ApoA1 lysine-to- glutamine mutants. Performed comprehensive structure-function analysis for WT and mutant proteins.• Mutagenesis coupled with structure-function analysis revealed the essentiality of two key residues that are responsible for the activity of ApoA1 without greatly perturbing the overall structure of the enzyme. Show less

• Studied scientific and legal documents to ensure compliance of company products with regulations set by the Medicines and Healthcare Products Regulatory Agency. • Maintained standards with changes in regulatory legislation and guidelines, and outlined requirements for labelling, storage, and packaging of various products.

Advanced Certificate, Clinical Laboratory Scientist Training

Biochemistry, Research And Development Management