Ankai Xu Email & Phone Number

San Francisco, Ca, Us

South San Francisco, California, Us

Lead Product Manager for an innovative digital platform that will enable healthcare providers to access diverse cell & gene therapies and enable the orchestration and scaling of personalized therapy value chains

South San Francisco, California, Us

South San Francisco, California, Us

South San Francisco, California, Us

- Collaborate cross-functionally to enable the successful development, implementation, and execution of robust clinical manufacturing purification processes for large-molecule therapeutics and contribute to FDA submissions- Lead and contribute to the purification process development for diverse therapeutic candidates in the early-stage portfolio as part of an Agile team - Lead a team in the development, release, and continuous improvement of a Tableau-powered department dashboard and website to improve knowledge management, resource management, and collaboration - Developed tools to expand high-throughput robotics capabilities to enable more efficient process development workflows

South San Francisco, California, Us

- Designed a new business process in collaboration with business manager to enable agile portfolio management and information sharing, which received leadership team endorsement for implementation - Managed a team to coordinate the annual resource planning and review process for the portfolio of technical development projects and successfully executed a two-day portfolio resource review meeting

South San Francisco, California, Us

Delivered impactful results across diverse areas of Biologics Technical Development: Rotation IV: Protein Analytical Chemistry- Developed a program that was jointly piloted in Research and Early Development and Technical Development to enable early identification of manufacturing liabilities in therapeutics Rotation III: Purification Development- Developed an automated, high-throughput method on Tecan robotic liquid handling systems that significantly increased the capacity for parallel screening of bispecific antibody process conditions Rotation II: Device Development- Led the design and execution of an internal formative human factors study, conducted device tolerance analysis, and performed device testing to support the development of a second generation combination product Rotation I:- Optimized and qualified a high-throughput LC-MS peptide mapping assay for use in process characterization and process validation studies

Ithaca, Ny, Us

Undergraduate teaching assistant for Introduction to Process Dynamics and Control (CHEME 3720)

Ithaca, Ny, Us

- Engineered the protein production machinery of E. coli cells using recombinant DNA technology with the goal of producing humanized glycoproteins- Constructed plasmids and evaluated glycosylation efficiency in E. coli following electroporation and expression using SDS-PAGE and western blot- Engineering Learning Initiatives Research Grant Recipient

Co-led a team in the ideation, design, and prototyping of a passive cooling device for vaccine transportation in resource poor communities that won 3rd place in the 2014 EWH Design Competition

South San Francisco, California, Us

- Elucidated the enzymatic pathways responsible for the formation of a molecular adduct that impacted product quality- Studied adduct formation through cell-free incubation studies and 10 liter E. coli fermentations

South San Francisco, California, Us

- Developed and optimized a RP-UPLC method for the quantification of antibody and chaperone species in E. coli fermentations- Evaluated a new automated bench-scale mechanical and ultrasonic homogenization technology and authored an internal technical report supporting system adoption