Arthur Thomas Email & Phone Number

Chipping Campden, GB

Oxford, United Kingdom

Proteus Associates is an international consultancy specializing in the applications of artificial intelligence to the life and bio-medical sciences. We have worked on a wide variety of projects in the sector, with clients ranging from start-up companies, to global pharma companies, universities, NGOs and governments. Most of these projects involve the use.

Santa Barbara, California, United States

Product development planning for an innovative magnetic resonance technique for measuring meso-scale tissue characteristics (“textures”) with application to cancer detection.

Santa Barbara, CA, USA

AI applied to IoT systems: development of anomaly detection algorithms based on generative adversarial networks (GANs) for sensor data, and of knowledge graphs (“digital twins”) for causal modelling of built environment systems.

Santa Barbara, California, USA

Support of European clinical trials of an innovative robotic surgical microscope. Consultancy on image fusion for microsurgery, and on use of video analytics/annotation for assessing and improving surgeon behaviours and skills.

Oxford, United Kingdom

Mentoring graduate students in biomedicine. Schools outreach activities. In 2014 I organised and chaired a seminar series on "Privacy Issues in Genomic Medicine," (https://www.oii.ox.ac.uk/events/series/privacy-issues-in-genomic-medicine) funded by the Balliol Interdisciplinary Institute and supported by the Oxford Internet Institute.

Working on several projects on collaborative infrastructures for life sciences research, on eHealth, and on applications of "big data" analytics to socially and economically important problems, the most recent being a knowledge fusion platform about factors affecting the health of honey bees -- an "internet of things" project. Correlation of online YouTube.

Oxford, United Kingdom

The Global Health Network (http://tghn.org), based at the Nuffield Dept. of Medicine, Oxford University, is a "virtual science park" (funded by the Bill and Melinda Gates Foundation and others) for web sites and collaboration networks supporting public health in developing countries. I've advised on their technical infrastructure to support clinical trials.

Santa Barbara, California Area

TrueVision produced innovative 3D visualization systems for microsurgery, including image-guided surgery. I was involved in training their surgical customers in ophthalmology and neurosurgery, and also consulting on development of an image fusion application for overlaying CT and MRI pre-operative data onto the live surgical image. TrueVision was sold to.

Oxford

Caristo is a young Oxford start-up which is commercialising a new biomarker for vascular inflammation (and hence heart attack risk) derived from non-invasive imaging. I was involved with seed round funding and a successful InnovateUK grant proposal, with planning the development their IT infrastructure and clinical analysis platform, and also investigated.

Oxford, United Kingdom

Oxford Data Science was a new company applying knowledge discovery and network science methods to problems in finance, the environment and healthcare.

Sunnyvale, CA USA And Oxford, UK

The Academy is a non-profit which aims to produce knowledge-bases and point-of-care tools to help physicians assess the impact of genomic variation on therapy choices, esp. in oncology.

Strategic and technical advice to SyBIT, the information technology platform of SystemsX.ch, the new Swiss National Initiative in Systems Biology

The preDiCT (www.vph-predict.eu) project, part of the EU-funded "Virtual Physiological Human" (VPH/Physiome) initiative, and led by my old Oxford teacher Prof. Denis Noble, was an ambitious and largely successful attempt to create "top to bottom" computational models of the human heart that can be used to predict the potential cardiac toxicity of drugs. I.

I was responsible for coordinating some of UCL's "translational medicine" initiatives, in particular with integrating research, preclinical and clinical imaging, and integrating genotypic and clinical information. See www.ucl.ac.uk/csm for more details.

CloudBroker is a company which aims to promote the adoption of "cloud computing" (sometimes called "on demand computing" or "software as a service") by helping application developers and users select the right cloud platform for their needs, and helping them to port their applications.

BioWisdom is one of the leaders in scientific knowledge management, and in particular the development of ontology-based knowledge management and analysis systems for drug discovery and development. It was acquired by Instem.

SwissBioGrid was a successful grass roots project to build a Grid computing infrastructure for life science research in Switzerland.

I helped to develop services of Vital-IT, the SIB's High-performance Computing centre in Lausanne, and to promote their use within the Swiss bio-pharmaceutical industry.

DynaFluidics developed innovative software-controlled microfluidics systems for mixing and separation, with applications to the life sciences.

GeneMark exploited a new technique for using synthetic DNA sequences for watermarking physical objects such as drug packaging in order to prevent counterfeiting.

Synomics was a pioneer in the application of CORBA-based middleware to data integration in the life sciences. It was eventually acquired by Accelrys.

Utra-high performance computers for pattern matching, which were applied to biological sequence analysis and text mining. It was eventually acquired by Celera Genomics.

EIS developed rule-based systems for financial planning and trading.

Sunnyvale, CA, USA

ADAC was a very innovative company where I helped develop some of the earliest digital image processing systems for medicine, including the first commercial digital angiography system, the first all-digital radiotherapy planning system and one of the first picture and archiving communications (PACS) systems. We were involved in the very early days of MRI.

I worked on what is now called "connectomics" -- trying to reconstruct the geometry and connectivity of neurons from electron micrographs. It turned out to be too hard then, but is now a burgeoning and very exciting field! I wish I could get involved again.

Ba (1St Class Hons), Physiology

Being an undergraduate at Balliol College was a truly formative experience. I was lucky enough to be taught by exceptional tutors.

Phd, Special Graduate Program/Artificial Intelligence

The Stanford AI Lab was one of the best places in the world for computer scientists in the 1970s. It pioneered many of the ideas which we.

Postdoctoral Fellow, Neurobiology

I worked on what is now called connectomics -- trying to reconstruct the geometry and connections of neurons from electron micrographs. It.