Arthur Thomas

Arthur Thomas Email and Phone Number

CEO, founder @ Proteus Associates
Chipping Campden, GB
Arthur Thomas's Location
Chipping Campden, England, United Kingdom, United Kingdom
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About Arthur Thomas

Oxford-trained physiologist, Stanford Ph.D. in Artificial Intelligence, who has worked for 40+ years at the interface between the biomedical sciences, computation, and information analysis and management. Serial bio-medical and IT entrepreneur: founder, co-founder or founding consultant for a half-dozen startup companies in biomedicine, national security and finance.Skills and experience include:• Medical imaging: advanced visualization, image fusion and image-guided surgery systems.• Data Mining: pattern discovery and recognition in massive and real-time data and text streams.• Information fusion: methods and architectures for integration of information from diverse sources into coherent views of particular domains (“situational awareness”). Fusion of imagery and other scientific and clinical information. Ontological engineering, knowledge graphs and meta-data methodologies that underpin knowledge fusion environments.• Computational systems biology: use of formal domain models and multi-physics, multi-scale simulation technologies for modelling the structure and dynamics of cellular and organ function.• High performance/capability computing: applied to modelling of complex systems and management of very large, complex data repositories and data mining on high-volume, real-time data streams. Development of specialized processors for large-scale scientific computations.• Strategic impact of informatics in biomedicine: impact of data-intensive research on fundamental understanding of biological systems, on drug discovery and development, and on clinical medicine. Advice to senior management of bio-pharmaceutical companies on strategic and technical issues relating to these areas.

Arthur Thomas's Current Company Details
Proteus Associates

Proteus Associates

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CEO, founder
Chipping Campden, GB
Arthur Thomas Work Experience Details
  • Proteus Associates
    Ceo, Founder
    Proteus Associates
    Chipping Campden, Gb
  • Proteus Associates
    Ceo, Founder
    Proteus Associates Jan 1985 - Present
    Oxford, United Kingdom
    Proteus Associates is an international consultancy specializing in the applications of artificial intelligence to the life and bio-medical sciences. We have worked on a wide variety of projects in the sector, with clients ranging from start-up companies, to global pharma companies, universities, NGOs and governments. Most of these projects involve the use of AI technologies for knowledge representation, inference, data mining and image analysis at scale.
  • Bioprotonics, Inc.
    Technical Consultant, Product Development
    Bioprotonics, Inc. Feb 2023 - Present
    Santa Barbara, California, United States
    Product development planning for an innovative magnetic resonance technique for measuring meso-scale tissue characteristics (“textures”) with application to cancer detection.
  • Pametan
    Chief Technology Advisor
    Pametan Feb 2021 - Present
    Santa Barbara, Ca, Usa
    AI applied to IoT systems: development of anomaly detection algorithms based on generative adversarial networks (GANs) for sensor data, and of knowledge graphs (“digital twins”) for causal modelling of built environment systems .
  • Truedigitalsurgery, Inc.
    Consultant
    Truedigitalsurgery, Inc. Jan 2019 - Present
    Santa Barbara, California, Usa
    Support of European clinical trials of an innovative robotic surgical microscope. Consultancy on image fusion for microsurgery, and on use of video analytics/annotation for assessing and improving surgeon behaviours and skills.
  • Balliol College, University Of Oxford
    College Advisor In Biomedical Sciences
    Balliol College, University Of Oxford Oct 2011 - Present
    Oxford, United Kingdom
    Mentoring graduate students in biomedicine. Schools outreach activities. In 2014 I organised and chaired a seminar series on "Privacy Issues in Genomic Medicine," (https://www.oii.ox.ac.uk/events/series/privacy-issues-in-genomic-medicine) funded by the Balliol Interdisciplinary Institute and supported by the Oxford Internet Institute.
  • Oxford Internet Institute
    Research Associate
    Oxford Internet Institute Sep 2007 - Present
    Working on several projects on collaborative infrastructures for life sciences research, on eHealth, and on applications of "big data" analytics to socially and economically important problems, the most recent being a knowledge fusion platform about factors affecting the health of honey bees -- an "internet of things" project. Correlation of online YouTube viewing behaviours and self-declared views related to climate change.
  • Global Health Network
    Technical Advisor, Member Of Sab
    Global Health Network Feb 2013 - Present
    Oxford, United Kingdom
    The Global Health Network (http://tghn.org), based at the Nuffield Dept. of Medicine, Oxford University, is a "virtual science park" (funded by the Bill and Melinda Gates Foundation and others) for web sites and collaboration networks supporting public health in developing countries. I've advised on their technical infrastructure to support clinical trials and infectious disease surveillance, including data mining of point of care diagnostic data in southern Africa, and mining of Twitter data about HIV and Ebola epidemics to understand how information and misinformation are disseminated. I’m currently working on the idea of using semantic annotations of the network content to improve search accuracy.
  • Truevision 3D Surgical
    Consultant
    Truevision 3D Surgical 2007 - Dec 2018
    Santa Barbara, California Area
    TrueVision produced innovative 3D visualization systems for microsurgery, including image-guided surgery. I was involved in training their surgical customers in ophthalmology and neurosurgery, and also consulting on development of an image fusion application for overlaying CT and MRI pre-operative data onto the live surgical image. TrueVision was sold to Alcon in December 2018. A successor company, TrueDigital Surgery, is currently introducing a new kind of robotic microscope for neurosurgery in collaboration with Aesculap.
  • Caristo Diagnostics
    Founding Consultant, Acting Cto
    Caristo Diagnostics Nov 2017 - Aug 2018
    Oxford
    Caristo is a young Oxford start-up which is commercialising a new biomarker for vascular inflammation (and hence heart attack risk) derived from non-invasive imaging. I was involved with seed round funding and a successful InnovateUK grant proposal, with planning the development their IT infrastructure and clinical analysis platform, and also investigated deep learning approaches to image segmentation. Caristo just raised a second round of funding, has received FDA 510k approval, and is expecting a CE Mark for its initial product very soon.
  • Oxford Data Science
    Co-Founder
    Oxford Data Science Jun 2013 - Apr 2018
    Oxford, United Kingdom
    Oxford Data Science was a new company applying knowledge discovery and network science methods to problems in finance, the environment and healthcare.
  • Academy Of Genomic Medicine
    Co-Founder
    Academy Of Genomic Medicine Nov 2012 - Dec 2014
    Sunnyvale, Ca Usa And Oxford, Uk
    The Academy is a non-profit which aims to produce knowledge-bases and point-of-care tools to help physicians assess the impact of genomic variation on therapy choices, esp. in oncology.
  • Systemsx.Ch
    Member, Sybit Management Board
    Systemsx.Ch Apr 2009 - Jun 2011
    Strategic and technical advice to SyBIT, the information technology platform of SystemsX.ch, the new Swiss National Initiative in Systems Biology
  • Oxford University, Dept. Of Physiology, Anatomy And Genetics
    Chair Of Sab For The Predict Project
    Oxford University, Dept. Of Physiology, Anatomy And Genetics 2007 - 2011
    The preDiCT (www.vph-predict.eu) project, part of the EU-funded "Virtual Physiological Human" (VPH/Physiome) initiative, and led by my old Oxford teacher Prof. Denis Noble, was an ambitious and largely successful attempt to create "top to bottom" computational models of the human heart that can be used to predict the potential cardiac toxicity of drugs. I also developed an exploitation plan for how the work of the project could be effectively transferred into commercial drug development.
  • University College London
    Principal Research Associate, Computational And Systems Medicine
    University College London Aug 2009 - Apr 2010
    I was responsible for coordinating some of UCL's "translational medicine" initiatives, in particular with integrating research, preclinical and clinical imaging, and integrating genotypic and clinical information. See www.ucl.ac.uk/csm for more details.
  • Cloudbroker, Zurich, Switzerland
    Co-Founder
    Cloudbroker, Zurich, Switzerland Nov 2008 - Apr 2010
    CloudBroker is a company which aims to promote the adoption of "cloud computing" (sometimes called "on demand computing" or "software as a service") by helping application developers and users select the right cloud platform for their needs, and helping them to port their applications.
  • Biowisdom (Now Instem)
    Co-Founder, Chair Of Sab
    Biowisdom (Now Instem) 2000 - 2008
    BioWisdom is one of the leaders in scientific knowledge management, and in particular the development of ontology-based knowledge management and analysis systems for drug discovery and development. It was acquired by Instem.
  • Swiss National Supercomputing Centre (Cscs)
    Consultant, Project Manager Swissbiogrid
    Swiss National Supercomputing Centre (Cscs) Jan 2005 - Jul 2007
    SwissBioGrid was a successful grass roots project to build a Grid computing infrastructure for life science research in Switzerland.
  • Swiss Institute Of Bioinformatics
    Consultant
    Swiss Institute Of Bioinformatics 2005 - 2007
    I helped to develop services of Vital-IT, the SIB's High-performance Computing centre in Lausanne, and to promote their use within the Swiss bio-pharmaceutical industry.
  • Dynafluidics
    Co-Founder
    Dynafluidics 2005 - 2006
    DynaFluidics developed innovative software-controlled microfluidics systems for mixing and separation, with applications to the life sciences.
  • Genemark
    Co-Founder
    Genemark 2003 - 2005
    GeneMark exploited a new technique for using synthetic DNA sequences for watermarking physical objects such as drug packaging in order to prevent counterfeiting.
  • Synomics
    Consultant, Member Sab
    Synomics 1998 - 2000
    Synomics was a pioneer in the application of CORBA-based middleware to data integration in the life sciences. It was eventually acquired by Accelrys.
  • Paracel, Inc., Pasadena, Ca
    Founding Consultant
    Paracel, Inc., Pasadena, Ca Jul 1992 - Oct 1998
    Utra-high performance computers for pattern matching, which were applied to biological sequence analysis and text mining. It was eventually acquired by Celera Genomics.
  • Experta Intelligent Systems, Zurich, Switzerland
    Senior Consultant
    Experta Intelligent Systems, Zurich, Switzerland 1990 - 1991
    EIS developed rule-based systems for financial planning and trading.
  • Adac Laboratories
    Senior Engineer
    Adac Laboratories 1978 - 1984
    Sunnyvale, Ca, Usa
    ADAC was a very innovative company where I helped develop some of the earliest digital image processing systems for medicine, including the first commercial digital angiography system, the first all-digital radiotherapy planning system and one of the first picture and archiving communications (PACS) systems. We were involved in the very early days of MRI, and I also worked on the development of an "expert system" for radiological diagnosis. ADAC was eventually acquired by Philips Medical.
  • University Of Lausanne, School Of Medicine
    Post-Doctoral Fellow
    University Of Lausanne, School Of Medicine 1977 - 1978
    I worked on what is now called "connectomics" -- trying to reconstruct the geometry and connectivity of neurons from electron micrographs. It turned out to be too hard then, but is now a burgeoning and very exciting field! I wish I could get involved again.

Arthur Thomas Skills

Computational Biology Artificial Intelligence Data Mining Life Sciences Bioinformatics Machine Learning Text Mining Image Processing High Performance Computing Drug Discovery Semantic Web Genomics Informatics Science Systems Biology Semantic Technologies Cloud Computing Lifesciences Pattern Recognition Computational Modeling Knowledge Representation Ontology Engineering Translational Medicine Translational Research Data Fusion Information Extraction Predictive Analytics Sentiment Analysis Semantic Search Semantics Computational Physiology Image Guided Surgery

Arthur Thomas Education Details

Frequently Asked Questions about Arthur Thomas

What company does Arthur Thomas work for?

Arthur Thomas works for Proteus Associates

What is Arthur Thomas's role at the current company?

Arthur Thomas's current role is CEO, founder.

What is Arthur Thomas's email address?

Arthur Thomas's email address is aj****@****tes.com

What is Arthur Thomas's direct phone number?

Arthur Thomas's direct phone number is +177583*****

What schools did Arthur Thomas attend?

Arthur Thomas attended Balliol College, University Of Oxford, Stanford University, University Of Lausanne - Unil.

What skills is Arthur Thomas known for?

Arthur Thomas has skills like Computational Biology, Artificial Intelligence, Data Mining, Life Sciences, Bioinformatics, Machine Learning, Text Mining, Image Processing, High Performance Computing, Drug Discovery, Semantic Web, Genomics.

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