Ashwini Patil Email and Phone Number
I am an expert in the computational analysis and visualization of large-scale biological data. I am currently working on the development of a comprehensive, high-quality cell type signature database called CellKb for the accurate annotation of cell types in single-cell and spatial RNA-seq datasets.Before becoming an entrepreneur, I spent 17 years in academia conducting research in the areas of single-cell data analysis, intrinsically disordered proteins, molecular interaction networks, protein structure analysis, protein structural modelling, protein function prediction and gene expression analysis.
Combinatics
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Chief Executive OfficerCombinatics Mar 2020 - PresentTokyo, JapanDevelopment of reliable databases with advanced search features by extensively curating, integrating, annotating and scoring biological data from literature:1. CellKb (https://www.cellkb.com), a database of extensively curated and annotated cell type marker gene sets collected from literature, and used to assign cell types in single-cell data.2. HitPredict (http://www.hitpredict.org), an open-source database of experimentally identified protein-protein interactions that are scored for reliability.
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Bioinformatics ConsultantCombinatics Mar 2020 - PresentTokyo, JapanCollaboration and consulting in biological data analyses projects:1. Bulk and single-cell gene expression analysis in systems immunology2. Analysis of chromatin accessibility in disease3. Analysis of tumor cell types in cancer using single-cell and spatial gene expression analysis4. Molecular network analysis in the mammalian immune response
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Lecturer (講師)The University Of Tokyo Sep 2014 - Aug 2019Institute Of Medical Science- Analysis of large-scale single-cell data to study the mammalian immune system- Analysis of organism-wide gene expression patterns to study the effects of pathogen exposure and vaccination in mammals- Prediction of 3D models of tumor-specific T-cell receptors for cancer immunotherapy- Prediction of binding sites in intrinsically disordered proteins using machine learning- Mentoring post-docs, PhD, Master's, Undergraduate, internship students- Grants - JSPS (PI), AMED (Co-PI) -
Assistant Professor (准教授)The University Of Tokyo Jan 2010 - Aug 2014Institute Of Medical Science- Development of an algorithm to predict gene response networks from gene expression profiles: TimeXNet (http://txnet.hgc.jp)- Study of structural and functional properties of intrinsically disordered proteins and their utility in protein function prediction- Identification of sequence features of degradation markers in proteasomal substrates- Mentoring post-docs, PhD, Master's, Undergraduate, internship students- Grants: JSPS (PI), Takeda Science Foundation (Co-PI)
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Postdoctoral ResearcherThe University Of Tokyo Jan 2009 - Dec 2009Institute Of Medical Science- Structural and sequence properties of intrinsically disordered proteins- Structural properties affecting the ability of hub proteins to bind multiple partner proteins- Structural and functional properties of proteins in interaction networks
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Domain Expert, BioinformaticsPersistent Systems 2007 - 2008Member of team working on the analysis of microarray gene expression data from tumor samples in collaboration with University of Washington, St. Louis. -
Research AssociateBioinformatics Center, University Of Pune 2006 - 2007Bioinformatics Center1. Research on the structural properties of highly interacting hub proteins.2. Taught course on Object Oriented and Relational Databases to Master's students.
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Software EngineerVeritas Technologies Llc 1999 - 2002Member of team developing a web-based backup monitoring tool in Java. -
Computational BiologistRosetta Biosoftware Mar 1999 - Sep 1999Member of team developing a microarray analysis software in Java. -
Software EngineerPtc 1996 - 1997Member of team developing a computer-aided mechanical parts design tool in C++.
Ashwini Patil Skills
Ashwini Patil Education Details
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Bioinformatics -
Molecular And Cellular Biology Coursework -
Biomedical Engineering
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Electronics And Telecommunications Engineering
Frequently Asked Questions about Ashwini Patil
What company does Ashwini Patil work for?
Ashwini Patil works for Combinatics
What is Ashwini Patil's role at the current company?
Ashwini Patil's current role is CEO Combinatics l PhD Bioinformatics | Single-cell multi-omics | Spatial transcriptomics | Cell type annotation.
What schools did Ashwini Patil attend?
Ashwini Patil attended Osaka University, The University Of Texas Southwestern Medical Center At Dallas, The University Of Texas Southwestern Medical Center At Dallas, College Of Engineering Pune.
What skills is Ashwini Patil known for?
Ashwini Patil has skills like Computational Biology, R, Systems Biology, Functional Genomics, Perl, Structural Bioinformatics, Gene Expression Analysis, Single Cell Data Analysis, Pathway Analysis, Molecular Networks, Biostatistics, Data Mining.
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