Benjamin Pratt Email and Phone Number
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Small molecule drug discovery and development scientist with success in transforming a novel idea to a tangible asset for pharmaceutical company acquisition. Project Leader and lead chemist of start-up company who managed a multinational and multidisciplinary team to generate a drug candidate currently in Phase 1 clinical trials.Synthetic organic Ph.D. chemist with hands-on experience in both medicinal and process chemistry on multi-step synthesis of pharmaceutically active compounds on milligram to kilogram scales. Discovery program leader managing chemical synthesis, biology testing, ADME and PK profiling and coordinating with pharmacology and toxicology leaders to complete IND. CMC team leader coordinating GMP process chemistry, formulation development, analytical development and regulatory filings through preparation for Phase 2 clinical trials. Experienced in discovery of novel development candidates for GI (gastroenterology), CNS (central nervous system), oncology targets.Extensive involvement with non-profit American Chemical Society San Diego Local Section: 2015 Chair, Co-founder of ACS-West Coast Analytical Chemistry Symposium, Co-founder and Lecturer of Academics to Industry lecture series.Specialties: Drug Discovery, Drug Development, Medicinal Chemistry, Natural Product Synthesis, Organic Chemistry, Process Chemistry, CMC, Drug Product Development, Team Building, Event Organization, Non-Profit Fundraising, Career Development, Public Outreach, Teaching
Vasa Therapeutics
View- Website:
- vasatherapeutics.com
- Employees:
- 8
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Co-Founder And Vp Of ChemistryVasa Therapeutics Oct 2019 - PresentSan Diego, California, United States -
Consultant - Medicinal And Process Chemistry For Small Molecule Drug Discovery And DevelopmentPratt Pharma Consulting Llc Mar 2018 - PresentGreater San Diego AreaConsultant for small molecule drug discovery and development from conception through to Phase 2 clinical trials.
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Associate Director, Chemical Development And Cmc Team LeaderAllergan Sep 2016 - Mar 2018Irvine, Ca- CMC Team Leader for Akarna (FXR) Program Core Team that took the Akarna Development Candidate through IND, into Phase 1 and prepared for Phase 2a clinical trials- Managed CMC activities including Process Chemistry, Analytical and Formulation Development, Drug Product Development, GMP API shipping, labeling and import- Collaborated with Clinical, Toxicology and Regulatory Core Teams leaders to push an aggressive timeline into and through the clinic- Chemistry Development representative for 5 other PreIND, Phase 1/2 programs at Allergan -
Associate Director, Chemistry And Program LeaderAkarna Therapeutics Nov 2014 - Sep 2016Greater San Diego Area- Discovered AKN-083, a small molecule non-bile acid FXR agonist for the treatment of NASH/NAFLD- Lead scientist and Program Leader of start-up company overseeing all aspects of drug discovery and development- 18-month incubation from Akarna's inception to sale of Pre-IND Discovery Candidate to Allergan- Close collaboration with pharmacologist and toxicologist to navigate animal efficacy and GLP toxicology studies on aggressive timescale
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Scientist IiDart Neuroscience Jan 2012 - Nov 2014Greater San Diego AreaMedicinal Chemist tasked with optimizing target hits through validation and lead optimization for optimal CNS properties. Close collaboration with structural biology, ADMET, DMPK and pharmacology teams to produce lead candidate for memory and cognition target. Development of process friendly route for lead compound and synthesis of non-GLP toxicology API. Managed associate scientist direct report.
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Research ScientistHelicon Therapeutics May 2010 - Jan 2012San Diego, Ca
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Research Scientist I - Medicinal ChemistryExelixis Apr 2009 - Mar 2010Synthesis of potent GPCR agonists for the treatment of Type II diabetes and Obesity. Outsourced an early stage project with Sai Advantium in India that became a lead optimization program. -
Research Scientist I - Medicinal ChemistryAmbit Biosciences Sep 2008 - Apr 2009Medicinal Chemistry Research of Selective Kinase Inhibitors
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ScientistRhodia Sep 2000 - Apr 2003Custom Synthesis and Process Research & Development -
InternPfizer Jun 1999 - Sep 1999Summer Intern with Process Research & Development group
Benjamin Pratt Skills
Benjamin Pratt Education Details
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Synthetic Organic Chemistry -
Chemistry
Frequently Asked Questions about Benjamin Pratt
What company does Benjamin Pratt work for?
Benjamin Pratt works for Vasa Therapeutics
What is Benjamin Pratt's role at the current company?
Benjamin Pratt's current role is Pharmaceutical Drug Discovery and Development Leader.
What is Benjamin Pratt's email address?
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What is Benjamin Pratt's direct phone number?
Benjamin Pratt's direct phone number is +185894*****
What schools did Benjamin Pratt attend?
Benjamin Pratt attended Scripps Research, Dartmouth College.
What are some of Benjamin Pratt's interests?
Benjamin Pratt has interest in Process Chemistry, Organic Chemistry, Biotechnology, Drug Development, Structure Based Drug Design, Natural Product Synthesis, Medicinal Chemistry.
What skills is Benjamin Pratt known for?
Benjamin Pratt has skills like Organic Chemistry, Lead Optimization, Medicinal Chemistry, Process Chemistry, Drug Discovery, Organic Synthesis, Drug Design, Synthetic Chemistry, Chemistry, Drug Development, Gpcrs, Lead Change.
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