Benjamin Pratt

Benjamin Pratt Email and Phone Number

Pharmaceutical Drug Discovery and Development Leader @ Vasa Therapeutics
Benjamin Pratt's Location
Encinitas, California, United States, United States
Benjamin Pratt's Contact Details

Benjamin Pratt personal email

About Benjamin Pratt

Small molecule drug discovery and development scientist with success in transforming a novel idea to a tangible asset for pharmaceutical company acquisition. Project Leader and lead chemist of start-up company who managed a multinational and multidisciplinary team to generate a drug candidate currently in Phase 1 clinical trials.Synthetic organic Ph.D. chemist with hands-on experience in both medicinal and process chemistry on multi-step synthesis of pharmaceutically active compounds on milligram to kilogram scales. Discovery program leader managing chemical synthesis, biology testing, ADME and PK profiling and coordinating with pharmacology and toxicology leaders to complete IND. CMC team leader coordinating GMP process chemistry, formulation development, analytical development and regulatory filings through preparation for Phase 2 clinical trials. Experienced in discovery of novel development candidates for GI (gastroenterology), CNS (central nervous system), oncology targets.Extensive involvement with non-profit American Chemical Society San Diego Local Section: 2015 Chair, Co-founder of ACS-West Coast Analytical Chemistry Symposium, Co-founder and Lecturer of Academics to Industry lecture series.Specialties: Drug Discovery, Drug Development, Medicinal Chemistry, Natural Product Synthesis, Organic Chemistry, Process Chemistry, CMC, Drug Product Development, Team Building, Event Organization, Non-Profit Fundraising, Career Development, Public Outreach, Teaching

Benjamin Pratt's Current Company Details
Vasa Therapeutics

Vasa Therapeutics

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Pharmaceutical Drug Discovery and Development Leader
Employees:
8
Benjamin Pratt Work Experience Details
  • Vasa Therapeutics
    Co-Founder And Vp Of Chemistry
    Vasa Therapeutics Oct 2019 - Present
    San Diego, California, United States
  • Pratt Pharma Consulting Llc
    Consultant - Medicinal And Process Chemistry For Small Molecule Drug Discovery And Development
    Pratt Pharma Consulting Llc Mar 2018 - Present
    Greater San Diego Area
    Consultant for small molecule drug discovery and development from conception through to Phase 2 clinical trials.
  • Allergan
    Associate Director, Chemical Development And Cmc Team Leader
    Allergan Sep 2016 - Mar 2018
    Irvine, Ca
    - CMC Team Leader for Akarna (FXR) Program Core Team that took the Akarna Development Candidate through IND, into Phase 1 and prepared for Phase 2a clinical trials- Managed CMC activities including Process Chemistry, Analytical and Formulation Development, Drug Product Development, GMP API shipping, labeling and import- Collaborated with Clinical, Toxicology and Regulatory Core Teams leaders to push an aggressive timeline into and through the clinic- Chemistry Development representative for 5 other PreIND, Phase 1/2 programs at Allergan
  • Akarna Therapeutics
    Associate Director, Chemistry And Program Leader
    Akarna Therapeutics Nov 2014 - Sep 2016
    Greater San Diego Area
    - Discovered AKN-083, a small molecule non-bile acid FXR agonist for the treatment of NASH/NAFLD- Lead scientist and Program Leader of start-up company overseeing all aspects of drug discovery and development- 18-month incubation from Akarna's inception to sale of Pre-IND Discovery Candidate to Allergan- Close collaboration with pharmacologist and toxicologist to navigate animal efficacy and GLP toxicology studies on aggressive timescale
  • Dart Neuroscience
    Scientist Ii
    Dart Neuroscience Jan 2012 - Nov 2014
    Greater San Diego Area
    Medicinal Chemist tasked with optimizing target hits through validation and lead optimization for optimal CNS properties. Close collaboration with structural biology, ADMET, DMPK and pharmacology teams to produce lead candidate for memory and cognition target. Development of process friendly route for lead compound and synthesis of non-GLP toxicology API. Managed associate scientist direct report.
  • Helicon Therapeutics
    Research Scientist
    Helicon Therapeutics May 2010 - Jan 2012
    San Diego, Ca
  • Exelixis
    Research Scientist I - Medicinal Chemistry
    Exelixis Apr 2009 - Mar 2010
    Synthesis of potent GPCR agonists for the treatment of Type II diabetes and Obesity. Outsourced an early stage project with Sai Advantium in India that became a lead optimization program.
  • Ambit Biosciences
    Research Scientist I - Medicinal Chemistry
    Ambit Biosciences Sep 2008 - Apr 2009
    Medicinal Chemistry Research of Selective Kinase Inhibitors
  • Rhodia
    Scientist
    Rhodia Sep 2000 - Apr 2003
    Custom Synthesis and Process Research & Development
  • Pfizer
    Intern
    Pfizer Jun 1999 - Sep 1999
    Summer Intern with Process Research & Development group

Benjamin Pratt Skills

Organic Chemistry Lead Optimization Medicinal Chemistry Process Chemistry Drug Discovery Organic Synthesis Drug Design Synthetic Chemistry Chemistry Drug Development Gpcrs Lead Change Laboratory Biotechnology Lc Ms Hplc Kinases Purification Biochemistry Clinical Development Analytical Chemistry

Benjamin Pratt Education Details

Frequently Asked Questions about Benjamin Pratt

What company does Benjamin Pratt work for?

Benjamin Pratt works for Vasa Therapeutics

What is Benjamin Pratt's role at the current company?

Benjamin Pratt's current role is Pharmaceutical Drug Discovery and Development Leader.

What is Benjamin Pratt's email address?

Benjamin Pratt's email address is bp****@****aol.com

What is Benjamin Pratt's direct phone number?

Benjamin Pratt's direct phone number is +185894*****

What schools did Benjamin Pratt attend?

Benjamin Pratt attended Scripps Research, Dartmouth College.

What are some of Benjamin Pratt's interests?

Benjamin Pratt has interest in Process Chemistry, Organic Chemistry, Biotechnology, Drug Development, Structure Based Drug Design, Natural Product Synthesis, Medicinal Chemistry.

What skills is Benjamin Pratt known for?

Benjamin Pratt has skills like Organic Chemistry, Lead Optimization, Medicinal Chemistry, Process Chemistry, Drug Discovery, Organic Synthesis, Drug Design, Synthetic Chemistry, Chemistry, Drug Development, Gpcrs, Lead Change.

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