Trained in both health services research and health economics, my research intersects the disciplines of comparative effectiveness research, patient-centered outcomes research, real world evidence, clinical informatics, and health technology assessment where I employ methods from epidemiology, biostatistics, and decision sciences to answer research questions in my areas of interest. I apply my expertise to evidence synthesis projects, where I conduct systematic reviews and employ Bayesian and frequentist methods to conduct network meta-analyses and meta-analyses. I explore the effectiveness of pharmacogenomic biomarker-guided medication use on clinical outcomes, using real world evidence in the context of electronic clinical data. I address decision problems in health technology assessment and outcomes research using preference-based methods, discrete choice experiments and multi-criteria decision analysis. My work is funded by AHRQ. I also lead projects funded by NCI, NHLBI, the NIA, and the VA. I am currently a co-investigator on the Electronic Medical Records and Genomics (eMERGE 4) Network and the Clinical Sequencing Evidence-Generating Research (CSER 2), both national consortia funded by NHGRI. I teach methods courses in both the Graduate and Doctor of Pharmacy Programs. I hold adjunct appointments in the Departments of Health Services and Biomedical Informatics; and am a member of the Institute for Public Health Genetics and the Plein Center for Geriatric Pharmacy Research. I am currently a Fulbright US Scholar (2021) at the University of Murcia, School of Medicine, Department of Health Services Research. I am a member of the Board of Directors of ISPOR-the leading professional society for Health Economics and Outcomes Research, an Associate Editor for the ISPOR journal Value in Health, and a member of the AcademyHealth Methods and Data Council.I am an Assistant Director of the AHRQ-funded Pacific Northwest Evidence-based Practice Center, an elected member of the Society for Research Synthesis Methodology, and served on the ISPOR Task Force that developed guidelines to conduct network meta-analyses. Prior to joining the faculty at the UW, I was an advanced practice (prescribing) clinical pharmacist and formulary lead at UCSF, where I served a term as president of the California Society of Health-System Pharmacists, earning their Lifetime Achievement Award for my leadership role in advancing the scope of practice for California pharmacists through legislation.