Hardware and Software Integration Consulting

◦ Wrote automated analytic software to apply sensor physics models to analytical data. Significantly improved quality and throughput.◦ Built predictive analytical models based on system design and control theory. Improved prediction performance 10x.◦ Automated feature extraction on dynamic data sets.◦ Automated correlation analysis and relevant signal extraction. 100x reduction in model inputs. Improved overall prediction by 5x.◦ Integrated hardware and data collection / storage solutions across multiple languages and environments.◦ Prototyped new optical metrology hardware with integrated real time software control. Demonstrated in-situ throughput gains of over 20x.◦ Designed, prototyped, integrated, and validated next generation optical detection methods enabling 50x higher sensitivity.◦ Leveraged new suppliers enabling best in world performance for next generation technologies.◦ Drove supplier performance improvements enabling new metrology.◦ Developed internal cost reduction paths for critical components. Improved overall performance at 20% existing cost.◦ Redesigned system control and signal processing support replacement hardware and validated performance.◦ Developed and maintained critical supplier engagements from scratch.◦ Negotiated overall cost savings between 30 and 40% with multiple suppliers.

◦ Designed, modeled, and optimized dynamic control systems.◦ Developed, implemented, and automated internal engineering tools.◦ Developed, and automated image processing and analysis methods.◦ Optimized, and automated internal calibrations, for improved performance and eliminated thousands in total costs.◦ Identified key manufacturing mistakes saving 100,000+ in tooling costs.◦ Eliminated redundant electronic components to meet COGS targets.◦ Developed, and validated alternative data processing methods for COGS reductions.◦ Guided and co-developed engineering installation tools.◦ Designed, simulated, tested, and verified unique image processing algorithms.◦ Developed, and implemented automatic tuning and installation software.

◦ Led AFSEM development team.◦ Interfaced with customers and collaborators realizing scientific goals and needs.◦ Oversaw mechanical, electronic, and software integration of components necessary for advanced microscopy development.◦ Developed advanced custom control algorithms for AFM applications.

◦ High-Speed AFM imaging of the dynamic properties of model membrane systems.◦ Integration of High-Speed AFM and optical microscopes for life-science applications.◦ Design and use of model based filters for High-Speed AFM.◦ Automated image processing of large data sets from High-Speed AFM.◦ Design, fabrication, and implementation of mechanical and electronic components for High-Speed AFM.

◦ Observed and identified membrane disruption mechanisms of nanoparticles.◦ Developed an analytical method relating nanoscale structure of bone to disease states.◦ Use of combination AFM and optical microscopes. Developed a design change that significantly improved optical contrast.◦ Observed and measured dynamic changes in nanoscopic membrane domains.

◦ Simultaneous mechanical testing and functional imaging of trabecular bone.◦ Design, and implementation of mechanical testing devices and control systems.