Brendon E. Cook Email & Phone Number

Remote

Cambridge, Massachusetts

▸ Led the development of PET tracer from preliminary design and in vitro studies, progressing to preclinical in vivo, followed by developing a scale-up approach for synthesis, CMC activities, and non-human primate studies in preparation for an INDa-submission for first-in-human testing▸ Spearheaded preclinical research projects across a range of therapeutic modalities and disease areas leading to the creation of 6 novel molecular tracers to enable decision making impacting pipeline and R&D… Show more ▸ Led the development of PET tracer from preliminary design and in vitro studies, progressing to preclinical in vivo, followed by developing a scale-up approach for synthesis, CMC activities, and non-human primate studies in preparation for an INDa-submission for first-in-human testing▸ Spearheaded preclinical research projects across a range of therapeutic modalities and disease areas leading to the creation of 6 novel molecular tracers to enable decision making impacting pipeline and R&D activities▸ Served as “biomarker lead” in the strategic development for three clinical drug candidates involving timeline and budget management, executive approvals, and team leadership resulting in all three programs advancement and on track for phase 1 studies▸ Primary contact for externally sourced preclinical imaging studies at Biogen, overseeing study design and ensuring timely execution of over 15 externally conducted studies Show less

Cambridge, Massachusetts

▪ Pioneered the first platform utilizing pretargeted imaging in the central nervous system, leading to presentation at an international conference and a manuscript under review.▪ Mobilized cross-functional teams developing and implementing PET imaging technology for pipeline-relevant projects resulting in a filed patent application.

▪ Independently conceived and executed novel studies in translational nuclear medicine in cancer, contributing significantly to 8+ projects in 4 years and resulting in 10+ publications and numerous conference presentations.▪ Hands-on experience in organic, biochemical and radiochemical synthesis and characterization, cell culture, imaging and therapy studies in vivo.▪ Mentored five undergraduate and high school students, provided advisory and research assistance.Primary Mentor:… Show more ▪ Independently conceived and executed novel studies in translational nuclear medicine in cancer, contributing significantly to 8+ projects in 4 years and resulting in 10+ publications and numerous conference presentations.▪ Hands-on experience in organic, biochemical and radiochemical synthesis and characterization, cell culture, imaging and therapy studies in vivo.▪ Mentored five undergraduate and high school students, provided advisory and research assistance.Primary Mentor: Dr. Brian M. Zeglis; Co-Mentor: Dr. Jason S. LewisThesis: “The Development of Novel Platforms for the Imaging of Cancer by Positron Emission Tomography” Show less

Doctor Of Philosophy (Ph.D.), Chemistry

Advanced courses in organic, inorganic, and quantum chemistry, in addition to courses on nanomaterials and radiochemistry.

Bachelor'S Degree, Biology And Chemistry