Jon Harper Email & Phone Number

Raleigh, NC, US

Raleigh-Durham, North Carolina Area

Research Triangle Park, NC

• Led analytical activities for developmental inhaled therapeutic program. Responsibilities included technical/HR management of a junior staff member, week-to-week management of analytical activities, assay.
• Provided analytical support for a developmental vaccine program. Responsibilities included developing and transferring analytical methods, analyzing samples, interpreting and communicating data to stakeholders, and.
• Transferred in an HPAE-PAD method for analysis of a polysaccharide vaccine. Successfully adapted/troubleshot the assay to function on a traditional HPLC rather than an ion chromatography system.
• Developed/transferred in a titrimetry method for determining acid content of a copolymer. This assay and the HPAD-PAD assay allowed the project team to provide compelling data to an external partner on feasibility of.
• Executed and assisted as technical leader on other assays including RP-HPLC (content and impurities), GPC, FT-IR, and next generation impaction.
• Collaborated with peers on teams focused on improving procurement of laboratory supplies and scheduling of HPLC/UPLC instruments.

Research Triangle Park, NC

• Managed multiple responsibilities including developing, transferring, qualifying, and validating analytical assays, interpreting and communicating data to stakeholders (cross-functional team members, management and.
• Represented the analytical development group on multiple teams/committees (sustainability, emergency response, candidate selection and procurement improvement). As part of the procurement improvement committee.
• Identified N-linked glycan and monosaccharide profiles of a glycoprotein, including the implementation of a new (to the company) approach to monosaccharide analysis.
• Transferred and qualified quantitative SDS-PAGE and Bioanalyzer methods on a compressed timeline despite significant technical challenges. Successfully performed troubleshooting of both assays, including working with.
• Supported forced degradation and stability studies for multiple projects with a 100% rate of meeting due dates.
• Supported implementation of a new microfluidic electrophoresis instrument which included coordination/ordering of accessories and external products, receiving external training and serving as an SME for colleagues.

Research Triangle Park, NC

• Responsibilities included developing, and validating analytical assays, performing release and stability testing, interpreting and communicating data to stakeholders (cross-functional team members and clients), and.
• Developed analytical procedures for testing product quality of inhalation products including HPLC, delivered dose, cascade/next generation impaction, particle/droplet size analysis, and FT-IR.
• Led a cross-functional team in streamlining procedures for all phases of the cleaning verification process. Achievements included significant reductions in repeat analyses and improved turnaround times. Presented.
• Developed a novel approach for performing cleaning verification of a highly labile molecule. Created a poster based on this work that was presented at a major conference.
• Managed all aspects of a small-scale forced degradation study including sample stressing, analytical testing, and results reporting.
• Created and executed a strategy for dose and cascade impaction testing for a nebulized drug product which was a first for the department.