Brian Jester Email & Phone Number

Évry, Île-De-France, France

• This company is developing the Next-Generation of Bio-produced Textile dyes. • The strains are engineered using our new Synthetic Genomic platform. • Customized genomes are designed for robust performance using proprietary AI tools. • Synthetic DNA is purchased and assembled into functional genomes using our newly invented in vitro and in vivo DNA assembly methods.• Addressing sustainability and the circular economy, we have invented new methods for extracting sugars from industrial waste (lignocellulose biomass).

Évry, Île-De-France, France

• Designed and engineered bacterial strains for industrial bio-production

Évry, Île-De-France, France

• Develop strains for long-term evolution studies

Évry, Île-De-France, France

• Investigated how bacterial chromosomal conformation influences gene expression.• Designed and developed Synthetic Biology tools for modifying and editing genomes.

Strasbourg, Grand Est, France

• Evaluated the impact of sRNA on S. aureus persistence. • Constructed strains and expression vectors for S. aureus.

Strasbourg, Grand Est, France

• Studied protein import and proteolytic processing within the mammalian mitochondria and how this impacts disease states. • Invented and developed a new method for the recombinant expression of eukaryotic proteins. • Adapted the Vaccinia expression platform to characterize proteolytic processing within mitochondria.

Illkirch-Graffenstaden, Grand Est, France

• Designed and constructed a suite of Gateway expression vectors for the vaccinia virus platform.• Designed and engineered HIV-based expression vectors to facilitate in vivo imaging of the HIV pre-integration complex.

Dublin, County Dublin, Ireland

• Began setting up this academic spin-out company to develop/market customised cell-based assays• Invented & validated a cell-based assay to identify new anti-microbial compounds• Obtained the Enterprise Ireland Commercialization Fund – Proof of Concept (PC/2006/133): Development of in vivo screening systems to identify novel therapeutic compounds for bacterial and human Lysyl-tRNA synthetases.

Dublin, County Dublin, Ireland

• Invented and developed a cell-based assay to identify inhibitors of lysyl-tRNA synthetases.• Developed expression vectors for the production of heterologous proteins and RNAs within B. subtilis.

Milwaukee, Wisconsin, United States

• Established this small business to provide contractual technical services for research support. • Responsible for the yeast culturing and propagation for all industrial brewery operations (domestic and international). • Perform complete microbiological analysis of plant yeast propagators.• Operation and maintenance of the sequencing platform and related software.

Milwaukee, Wisconsin, United States

• Developed a quantitative antibody-based assay to evaluate the concentration of Cytochrome P450 CYP2E1 in human white blood cells. • Grew and maintained several different cell lines. Routinely quantitated gene expression within rat and human cell cultures. • Designed a PCR-based assay to genotype sampled populations for a genetic polymorphism linked to cancer.

Milwaukee, Wisconsin, United States

• Cloned genes into yeast expression vectors. • Expressed, isolated and assayed the activity of several proteins in vitro. • Developed an in vivo assay for flavor stability. • Designed and optimized a yeast biotransformation procedure to produce a hop flavor extract.• Developed several new beverage products using pilot fermentations. • Assisted in the scale-up of research projects to large-scale fermentations.

Doctor Of Philosophy - Phd, Genetics

Thesis : A Study of the Class I and the Class II Lysyl-tRNA Synthetases Using B. subtilis. This work was functional genomic study where we.

Master Of Science - Ms, Biology, General

Thesis: Defining the Minimum Genetic Requirements for Photosynthetic Growth in Rhodospirillum rubrum. This was a classical genetic study.

Bachelor Of Science - Bs, Biology