Brian Tomkowicz, Phd Email and Phone Number
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Innovative Scientific Leader in Biotech and Advanced TherapiesWith close to 20 years in the biotech, pharmaceutical, and CDMO sectors, I am a driven scientific leader with a track record of success in advancing next-generation gene therapies. Leveraging my expertise in viral vector platforms, including AAV, Lentivirus, and Adenovirus, I bring a deep understanding of viral-based gene therapies from concept to scale-up, ensuring rigorous standards and breakthrough outcomes.In high-growth and start-up environments, I excel at building and leading cross-functional teams that deliver results. My strategic approach to corporate growth is paired with a hands-on commitment to project management, positioning my teams to achieve milestones on time and under pressure.As a subject matter expert in AAV gene therapy and viral vector design, I continuously seek innovative solutions, especially in CRISPR/gene editing and cell line development, to push the boundaries of what's possible in the therapeutic landscape.
Sk Pharmteco
View- Website:
- skpharmteco.com
- Employees:
- 1641
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Head Of Research And DevelopmentSk PharmtecoNorth Wales, Pa, Us
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Vice-President Head Of R&D And Virology FellowSk Pharmteco Oct 2024 - PresentRancho Cordova , California, Us
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Sr. Director, Vector Engineering & ManufacturabilityCenter For Breakthrough Medicines At Discovery Labs Apr 2021 - Sep 2024King Of Prussia, Pennsylvania, UsHead of R&D: AAV, Lenti viral vector engineering, upstream and downstream processing (USP/DSP), viral analytics and cell line engineering. Next-gen plasmid design, innate immune responses during virus production and integration of external technology to improve virus manufacturing. -
Sr. Principal Investigator, Aav Gene Therapy And Viral ManufacturingThe Janssen Pharmaceutical Companies Of Johnson & Johnson Apr 2019 - Apr 2021Raritan, New Jersey, UsResearch efforts focused on development of AAV and lentiviral manufacturing platforms. Keen interest in improved production, purification, and vector engineering. Secondary interest in utilizing AAV/LV as delivery vehicle for cell/tissue specific targeting of therapeutic proteins and CAR-Ts. -
Principal Research Investigator, Aav Gene TherapyThe Janssen Pharmaceutical Companies Of Johnson & Johnson Oct 2017 - Apr 2019Raritan, New Jersey, Us
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Senior Research Scientist, Gene & Cell TherapyThe Janssen Pharmaceutical Companies Of Johnson & Johnson Jan 2015 - Oct 2017Raritan, New Jersey, UsGene and Cell Therapy
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Senior Research Scientist, Janssen Biotherapeutics At Janssen R&DThe Janssen Pharmaceutical Companies Of Johnson & Johnson Sep 2013 - Dec 2014Raritan, New Jersey, UsResponsible for new target Identification and validation. Research efforts focused on development efforts for oncology-, immuno-oncology-, and CVM antibody-based therapeutics.
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Senior Research Scientist, Centyrex VentureThe Janssen Pharmaceutical Companies Of Johnson & Johnson Aug 2011 - Aug 2013Raritan, New Jersey, UsPrimarily focused on platform development of alternative protein scaffolds called Centyrins. Strong emphasis on biochemical and cell based assay development as well as development of efficient high-throughput screening assays.
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Johnson & Johnson Innovation, JpalJohnson & Johnson Oct 2018 - Apr 2021New Brunswick, Nj, Us -
Group Leader, Antibody DevelopmentMorphotek, Inc. Jun 2010 - Aug 2011Therapeutic antibody development. Performed pre-clinical MOA studies for MORAb-003 (Farletuzumab) (FRa), MORAb-004 (Ontecizumab) (TEM-1/Endosialin), and other oncology targets.Integral member of clinical science sub-committee and diagnostic development teams serving as a medical science liaison for oncology programs.
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Senior Scientist, Antibody DevelopmentMorphotek, Inc. Sep 2007 - Jul 2010Human Antibody Development
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Post-Doctoral FellowMorphotek, Inc. Sep 2006 - Aug 2007Antibody/HTS Assay Development
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Post-Doctoral FellowUniversity Of Pennsylvania Jul 2005 - Aug 2006Philadelphia, Pa, UsTopic: “Signaling Crosstalk between the Bcr/Abl oncoprotein and Chemokine Receptors.”• Examine the mechanism(s) of how Bcr/Abl de-regulates chemokine signaling through CXCR4.• Utilize Lyn siRNA and other Lyn inhibitors to determine the potential of Lyn as a valid drug target in Bcr/Abl dependent malignant cell movement and survival.• Through a process called “inside-out” signaling, determine the linkage between Lyn kinase and integrins, and how Bcr/Abl affects this signaling process. -
Post-Doctoral FellowUniversity Of Pennsylvania Sep 2002 - Jul 2005Philadelphia, Pa, UsProject: “gp120-Induced Signaling in Human Monocyte-derived Macrophages.”• Investigated signaling pathways in human monocyte-derived macrophages in response to receptor engagement of CCR5 by MIP-1beta and HIV-1 gp120.• Focused specifically on examining the activation of PI3, Src and MAPK families and determined how activation of these kinases correlates with biological function.• Examined the expression patterns of selected chemokines following stimulation of macrophages with HIV-1 envelope.
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Co-Op, Angiogenesis ResearchJanssen, Pharmaceutical Companies Of Johnson And Johnson May 1996 - Aug 1997Raritan, New Jersey, UsJanssen Research Foundation, Springhouse, PAAngiogenesis Research Tested lead angiogenic compounds for in vitro cellular toxicity Evaluated lead compounds for their effect on tumor formation in mice. Examined PK profile of lead compounds in monkeys.
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Co-Op, Structural ChemistryGsk May 1995 - Jan 1996Brentford, Middlesex, GbSmithKline Beecham Pharmaceuticals, Upper Merion, PAX-Ray Crystallography• Responsible for the crystallization of small molecules • Determined structures using X-ray diffraction.
Brian Tomkowicz, Phd Skills
Brian Tomkowicz, Phd Education Details
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Thomas Jefferson UniversityMolecular Virology And Microbiology -
Penn State UniversityMicrobiology
Frequently Asked Questions about Brian Tomkowicz, Phd
What company does Brian Tomkowicz, Phd work for?
Brian Tomkowicz, Phd works for Sk Pharmteco
What is Brian Tomkowicz, Phd's role at the current company?
Brian Tomkowicz, Phd's current role is Head of Research And Development.
What is Brian Tomkowicz, Phd's email address?
Brian Tomkowicz, Phd's email address is br****@****msn.com
What schools did Brian Tomkowicz, Phd attend?
Brian Tomkowicz, Phd attended Thomas Jefferson University, Penn State University.
What are some of Brian Tomkowicz, Phd's interests?
Brian Tomkowicz, Phd has interest in Politics, Science And Technology, Economic Empowerment, Health.
What skills is Brian Tomkowicz, Phd known for?
Brian Tomkowicz, Phd has skills like Molecular Biology, Immunology, Assay Development, Cell, In Vitro, Biotechnology, Oncology, Antibodies, Life Sciences, Monoclonal Antibodies, Biomarkers, Cancer Research.
Who are Brian Tomkowicz, Phd's colleagues?
Brian Tomkowicz, Phd's colleagues are Yongji Seonwoo, Jeff Robinson, Joonheon (Jacob) Lee, Anastasia Piccinini, 조인구, John Breznicky, Jeff Kinkead.
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