Bryan Bear Email & Phone Number

St. Louis, Mo, Us

Greater St. Louis Area

• Manage daily clinical operations for research trials• Act as a liaison between research staff and treatment staff to streamline research visits for patients participating in clinical studies• Work with clinical research staff by identifying risks and developing an action plan to resolve any potential issues prior to patient arrival• Provide clinical research coordinators with support and direction• Assist with organization, implementation, and management of complex phase I-III clinical projects for solid tumor and bone marrow transplant to ensure trials are conducted in accordance to the protocol and standard operating procedures (SOPs) & work instructions (WIs). • Excellent ability to understand intricate protocols (e.g. treatment regimens, dose limiting toxicities, dose holding parameters, etc.) • Utilize a robust medical terminology arsenal to easily interpret lab results, orders, and treatment records.• Review patient lab/diagnostic testing results to ensure no dose modifications or holds are required prior to study drug preparation • Ability to effectively communicate and apply strong diplomacy skills to communicate difficult issues effectively with all levels of staff and faculty• Ensure medications are administered in the appropriate order, vital signs, and pharmacokinetics (PKs) are completed in accordance with the study protocol• Attend regularly scheduled Treatment Event Reporting meetings to review study treatment errors and discuss potential solutions in an effort avoid similar problems in the future • Serve on multidisciplinary order writing committee to generate protocol specific chemotherapy orders• Coordinate with research pharmacy to do regular audits of study specific Dose Administration Logs

Greater St. Louis Area

• Reviewed and presented financial disclosure statements for review by the Disclosure Review Committee (DRC) Chair• Processed transactional disclosures of financial interest and coordinated management with various University offices• Made initial determination of Financial Disclosure Statements to determine the nature of potential conflict of interest• Generated official correspondence (on behalf of the DRC Chair) implementing and maintaining conflict of interest management plans• Prepared case specific materials for DRC Subcommittee meetings• Communicated with faculty to clarify issues of conflict and provide guidance and education on conflicts of interest

Greater St. Louis Area

• Conducted quality assurance audits of clinical studies (trial master files) to ensure trials are conducted in accordance with the protocol, any/all appropriate regulatory agencies, local and institutional requirements• Applied clinical experience to understand intricate protocols (e.g. objectives, treatment regimens, dose limiting toxicities, dose holding parameters, etc.) • Utilized a robust medical terminology arsenal to easily interpret doctor notes, lab results, orders, treatment records, diagnostic testing and pathology reports. • Used strong investigative skills to identify and confirm initial and continued patient eligibility• Employed and understood vetted resources to confirm concomitant medications are appropriate for enrollment as well as throughout trial. • Identified and summarized protocol deviations and Serious Adverse Event occurrences• Ensured the consenting process was carried out appropriately• Cultivated strong relationships between all clinical teams to encourage open lines of communication in an effort to fully understand practices form the clinical team perspective, along with providing education & and guidance on regulatory, local, institutional, and divisional requirements• Maintained records of monitoring review for retrieval and analysis• Presented audit findings to the QA/QI Committee• Participated in analysis of data to develop educational processes for research community with the intent of achieving systemic process improvements

Greater St. Louis Area

Department of Psychiatry• Coordinated and managed research projects for the Alzheimer’s Disease Research Center and the Conte Center for Neuroscience Research• Reviewed and cross-checked protocols with Case Report Forms for consistency within each document• Carried out the consenting process with potential research participants• Performed eligibility checks on potential research study participants• Prepared amendments and continuing review applications for IRB review and approval• Performed Magnetic Resonance Imaging (MRI) scans on research participants with Alzheimer’s disease and Schizophrenia• Scheduled and implemented participant visits, labs, and diagnostic testing according to protocol• Conducted in home study visits• Planned and implemented new processes for an upgraded MRI platform• Attended calibrations sessions for structured clinical interviews for Schizophrenia studies• Gave recruitment presentations to various types of mental health professionals and consumers• Served on subject recruitment committee

Greater St. Louis Area

• Acted as a liaison between physicians, nurses, accountants, and pharmacists• Produced monthly accounting reports• Prepared reports of antipsychotic medication usage trends to the Missouri Department of Mental Health• Facilitated yearly inventory audit with the Missouri Department of Mental Health accounting department• Developed and implemented new process for inventory maintenance• Processed and delivered physician’s orders