Carlos Paz Email & Phone Number

Texas, United States

Irving, Tx

-Developed multi-color flow cytometry based assays in support of successful IND application and forthcoming clinical trial-Maintained cultures of human iPSC, primary human umbilical cord multipotent mesenchymal stromal cells, and primary human immune cells-Developed, validated, and transferred SOPs from R&D to Manufacturing Dept for the preparation, execution, and analysis of MSC/T-cell co-culture assay.-Designed and oversaw overhaul of daily data recording protocols for mammalian cell culture in R&D.

Dallas, Texas, United States

Advisors: James J. Collins III and Melanie Cobb•Developed and conducted project to characterize novel pharmacological targets, protein kinases STK25 and TAO, in an emerging stem cell model organism, the human parasite Schistosoma mansoni• Discovered that these kinases coordinately regulate a muscle-specific transcriptional program, which when disrupted causes worm posterior paralysis and death in vivo. Results published in "Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni." (Wang, Paz, et. al., Science 2020)• Howard Hughes Medical Institute Gilliam Fellowship• NIH Pharmacological Sciences Predoctoral Research Training Program• National Science Foundation Graduate Research Fellowship Program

Dallas, Texas, United States

• Liaison between leaders in graduate and medical school administration and graduate/postdoc populations in support of activities advancing SACNAS mission• Coordinated with faculty and student bodies to organize professional development seminars of interest to our graduate student and postdoc populations• Speaker at HACEMOS Fort Worth, a community event serving about 200 local families with college-bound high school seniors• Expanded SACNAS at UTSW chapter membership from 10 to 63 through implementation of monthly recruiting events

Advisor: Rama Ranganathan• Utilized deep sequencing to determine the effect of thermodynamic fold stability on the evolvability of proteins, using the model PDZ3 and an algorithmically designed destabilized PDZ3 syntholog.

Dallas, Texas, United States

• Liaison between local SACNAS chapter and national organization• Organized bilingual educational booth aimed at dispelling common health myths in the Hispanic community at 2017 "Carnaval de Salud" community health fair• Spanish-English translator between medical personnel and non-scientist attendees at 2016 "Carnaval de Salud" community health fair• Organized "Unconscious Bias" seminar to increase campus-wide awareness of cultural attitudes towards race.

La Jolla, Ca

• Research fellowship funded by California Institute for Regenerative Medicine• In the lab of Jeanne Loring, PhD, optimized culture conditions for stable proliferation of midbrain dopaminergic progenitor cells derived from human induced pluripotent stem cells as part of preclinical autologous cell therapy research.• For this research, received Provost Award for Outstanding Poster at 2015 SDSU student research symposium. • Led lab tours for both scientists and non-scientists interested in Parkinson's disease research at the Loring lab • Educated the general public about Loring lab research at several Parkinson’s disease awareness and fundraising events

Miami, Fl

• National Science Foundation REU grant recipient for summer undergraduate research• In the lab of Yuk-Ching Tse-Din, PhD, performed a high-throughput screen of a chemical library in the search for a Topoisomerase 1A poison inhibitor. Discovered thirteen candidates with strong topoisomerase-inhibition activity, results included in publication "Small- Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents” (Sandhaus S et al, 2016)•For this research, received an Outstanding Presentation Award at ABRCMS, Nov 2014.

Rutgers University, New Jersey

• Green Energy Technology Undergraduate Program (GET UP) for undergraduate summer research• In the lab of Eric Lam, PhD, quantified methionine content in 5 genera of duckweed, a potential biofuel feedstock with numerous “green” applications.

San Diego, Ca

• In the lab of Elizabeth Dinsdale, PhD, performed lab assistant duties in support of marine metagenomics research, including PCR, bacterial culture, DNA extraction, Tangential Flow Filtration, DNA quantification.• American Chemical Society Scholar 2012

San Diego, California, United States

• Graduate-school-preparatory internship

El Cajon, California, United States

• Tutored all levels of math from basic arithmetic up to calculus 3 (multivariable calculus), as well as basic statistics and basic physics.• For my work as a tutor, received 2012 Grossmont College "Man of Distinction" award recognizing "outstanding contributions to improving the quality of life on campus"

San Diego, California, United States

• Determined and delegated daily responsibilities for a store with average daily sales of 3-5 thousand dollars. • Loss prevention strategies training and enforcement. • During shifts as the senior staff member, oversaw a staff of 4-7 people, with responsibility for store layout and appearance, and primary contact for customer complaints and fulfillment.

Ph.D., Cell/Cellular And Molecular Biology

Activities and Societies: SACNAS, UTSW Soccer, Carnaval de Salud

B.S., Chemistry/Biochemistry

Activities and Societies: Bridges to the Baccalaureate, Marching Band

Education record

Activities and Societies: Phi Theta Kappa

Education record

Activities and Societies: Phi Theta Kappa