Chaemin Lim Email and Phone Number
Chaemin Lim personal email
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Dr. Chaemin Lim has a multidisciplinary scientific background with over 15 years of experience in academia and biopharma drug development covering multiple therapeutic areas. She is currently the Chief Scientific Officer of A2A Pharmaceuticals, a New York-based private biotech company that uses a proprietary computational platform to accelerate drug discovery and development. She is responsible for overall scientific, programmatic, financial oversight of A2A’s projects and managing collaborations and partnerships. She is an experienced leader of integrated teams and committed to bringing innovative solutions to the company for overcoming multifaced pharmaceutical R&D challenges with her broad experience in medicinal and computational chemistry to accelerate early therapeutic discovery to clinical stages. - Extensive research experience in synthetic medicinal chemistry, chemical biology, and drug discovery including broad hands-on experience with computational tools such as molecular modeling, quantitative structure-activity relationship models (QSAR), cheminformatics, and ML/AI tools. Facilitated early-stage drug discovery projects from the initial stages to preclinical development.
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Chief Technology OfficerCoiled TherapeuticsNew York, Ny, Us
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Chief Scientific OfficerA2A Pharmaceuticals May 2018 - PresentOur mission is to leverage proprietary computational systems, including A.I., to accelerate development of novel drug alternatives for life threatening diseases like cancer, bacterial infections and muscular dystrophy.At A2A Pharmaceuticals, I am responsible for overall scientific, programmatic, administrative, and financial oversight of the project to advance A2A’s pipeline and scientific platform. I work directly with and supervise A2A Pharmaceuticals personnel and fee-for-service contract research organizations (CROs) to carry out the proposed studies and analyses. I conduct research on ‘hit to lead’ development processes as well as lead optimization and preclinical development. Additionally, I am developing A2A’s target-specific workflow using machine learning (ML) and artificial intelligence (AI) tools. -
Postdoctoral Research FellowUniversity Of Pittsburgh Sep 2014 - Aug 2017Pittsburgh, Pa, UsAdvisor: Dr. Peter Wipf• Developed mitochondria-targeting ROS generators (XJB-Lapachone) for the treatment of cancer.• Synthesized JP4 analogs with improved PK properties leading to highly skin permeable analogs for a potential topological application as radiation mitigators.• Independently designed and synthesized active AZD6738 analog suitable for affinity tagging and prepared analog linked beads as well as a biotin conjugated AZD6738 analog.• Collaborated with researchers in a variety of fields. -
Research FellowUniversity Of Pittsburgh Chemical Diversity Center Sep 2014 - Aug 2017PI: Dr. Donna Huryn• Extensively contributed to drug discovery project in the NCI’s Chemical Biology Consortium (CBC). • Developed structure-based and ligand-based models for discovery of small molecule inhibitors of the AAA ATPase p97.• Constructed an in-house Mercaptophile Library (300 thiol-reactive compounds) from ~52,000 UPCMLD Library to identify small molecule inhibitors of ATG4b.• Evaluated and prioritized ~3,000 hits from high-throughput screening (HTS) to initiate a medicinal chemistry program targeting the Artemis Endonuclease. Synthesized analogs of active hits to develop small molecule inhibitors of the Artemis.• Worked with team members and actively involved in weekly/monthly based team meetings.• Worked with CROs to accomplish project tasks; assisted in key intermediate synthesis by providing optimized synthetic route and experimental procedures for p97 project.
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Research AssociateResearch Institute Of Pharmaceutical Sciences, Seoul National University Apr 2013 - Jul 2014Advisor: Dr. Sanghee KimResearch on small molecule and chemical probe synthesis• Developed a solid-supported chemodosimetric fluorescent probe.• Collaborated with researchers in a variety of fields, both locally and internationally.• Wrote and assisted with grants, patents and manuscripts.• Supervised graduate and undergraduate students.
Chaemin Lim Skills
Chaemin Lim Education Details
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Seoul National UniversityMedicinal And Pharmaceutical Chemistry -
Chosun UniversityPharmacy
Frequently Asked Questions about Chaemin Lim
What company does Chaemin Lim work for?
Chaemin Lim works for Coiled Therapeutics
What is Chaemin Lim's role at the current company?
Chaemin Lim's current role is Chief Technology Officer.
What is Chaemin Lim's email address?
Chaemin Lim's email address is ch****@****ail.com
What schools did Chaemin Lim attend?
Chaemin Lim attended Seoul National University, Chosun University.
What skills is Chaemin Lim known for?
Chaemin Lim has skills like Medicinal Chemistry, Drug Design, Computational Chemistry, Organic Synthesis, Combinatorial Chemistry, Cheminformatics, Drug Discovery, Schrodinger, Discovery Studio, Gaussian 09, Analytical Techniques, Nmr Spectroscopy.
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