Cody Hendren Email & Phone Number

Kansas City, Kansas, United States

Analyst for nonclinical drug transport and drug interaction studies in compliance with Good Laboratory Practice Standards (GLP) of the FDA (U.S. Food and Drug Administration) and/or the OECD (Organisation for Economic Co-operation and Development) and the MHLW (Japanese Ministry of Health, Labour and Welfare). Job responsibilities include designing and conducting in vitro drug transport, drug inhibition, drug metabolism, qPCR assays in correspondence with Study Protocols and Standard Operating… Show more Analyst for nonclinical drug transport and drug interaction studies in compliance with Good Laboratory Practice Standards (GLP) of the FDA (U.S. Food and Drug Administration) and/or the OECD (Organisation for Economic Co-operation and Development) and the MHLW (Japanese Ministry of Health, Labour and Welfare). Job responsibilities include designing and conducting in vitro drug transport, drug inhibition, drug metabolism, qPCR assays in correspondence with Study Protocols and Standard Operating Procedures (SOPs) with a focus in custom study design. Studies include assessment of inhibition and substrate efflux, uptake, and vesicle assays utilizing various immortalized cell lines (HEK293, MDCKII, Caco-2, and Fa2N-4), the harvest of RNA from cultured hepatocytes, RNA isolation, and reverse transcription, through qPCR, Cytochrome P450 Reaction Phenotyping, Metabolite Characterization, Metabolic Stability, Red Blood Cell Partitioning, and IC50 determination in various test systems (subcellular fractions, suspended hepatocytes). Other job responsibilities include conducting routine and non-routine laboratory functions and maintenance, focused research and development projects, perform data processing and verification, maintain accurate records and logs, and respond to in-house Quality Assurance audit reports, write and review SOPs, creating and improving training methodologies, training of new analysts on laboratory procedures. Proficient in the use of liquid scintillation counters, Synergy plate readers, Microbeta2 plate readers, Tecans, KingFisher Flex, Nanodrop, and AB 7900HT. Show less

Kansas City, Kansas, United States

Analyst for nonclinical drug transport and drug interaction studies in compliance with Good Laboratory Practice Standards (GLP) of the FDA (U.S. Food and Drug Administration) and/or the OECD (Organisation for Economic Co-operation and Development) and the MHLW (Japanese Ministry of Health, Labour and Welfare). Job responsibilities include designing and conducting in vitro drug transport assays in correspondence with Protocols and Standard Operating Procedures (SOPs). Studies include assessment… Show more Analyst for nonclinical drug transport and drug interaction studies in compliance with Good Laboratory Practice Standards (GLP) of the FDA (U.S. Food and Drug Administration) and/or the OECD (Organisation for Economic Co-operation and Development) and the MHLW (Japanese Ministry of Health, Labour and Welfare). Job responsibilities include designing and conducting in vitro drug transport assays in correspondence with Protocols and Standard Operating Procedures (SOPs). Studies include assessment of analyte stability and non-specific binding, inhibition and substrate efflux, uptake, and vesicle assays utilizing various immortalized cell lines (HEK293, MDCKII, Caco-2, and Fa2N-4), the harvest of RNA from cultured human hepatocytes, RNA isolation, reverse transcription, quantitative real-time polymerase chain reaction, (qPCR), BCA, Lucifer Yellow and Lactate Dehydrogenase (LDH) assays. Other job responsibilities include conducting routine and non-routine laboratory functions and maintenance, focused research and development projects, perform data processing and verification, maintain accurate records and logs, and respond to in-house Quality Assurance audit reports, write and review SOPs, creating and improving training methodologies, training of new analysts on laboratory procedures and personal training on team scheduling practices as well as leadership training for future growth opportunities. Proficient in the use of liquid scintillation counters, Synergy plate readers, Microbeta2 plate readers, Tecans, KingFisher Flex, Nanodrop, and AB 7900HT. Show less

Kansas City, Kansas

Analyst for nonclinical drug transport and drug interaction studies in compliance with Good Laboratory Practice Standards (GLP) of the FDA (U.S. Food and Drug Administration) and/or the OECD (Organisation for Economic Co-operation and Development) and the MHLW (Japanese Ministry of Health, Labour and Welfare). Job responsibilities include designing and conducting in vitro drug transport assays in correspondence with Protocols and Standard Operating Procedures (SOPs). Studies include inhibition… Show more Analyst for nonclinical drug transport and drug interaction studies in compliance with Good Laboratory Practice Standards (GLP) of the FDA (U.S. Food and Drug Administration) and/or the OECD (Organisation for Economic Co-operation and Development) and the MHLW (Japanese Ministry of Health, Labour and Welfare). Job responsibilities include designing and conducting in vitro drug transport assays in correspondence with Protocols and Standard Operating Procedures (SOPs). Studies include inhibition and substrate efflux, uptake, and vesicle assays utilizing various immortalized cell lines (HEK293, MDCKII, Caco-2, and Fa2N-4), the harvest of RNA from cultured human hepatocytes, RNA isolation, reverse transcription, quantitative real-time polymerase chain reaction, (qPCR), and Lactate Dehydrogenase (LDH) assays. Other job responsibilities include conducting routine laboratory functions and maintenance, research and development projects, perform data processing and verification, maintain accurate records and logs, and respond to in-house Quality Assurance audit reports, ownership and review of SOPs, and training of new analysts on laboratory procedures. Proficient in the use of liquid scintillation counters, Synergy plate readers, Microbeta2 plate readers, Tecans, KingFisher Flex, Nanodrop, and AB 7900HT. Show less

Kansas City, Ks

Analyst for nonclinical drug transport and drug interaction studies in compliance with Good Laboratory Practice Standards (GLP) of the FDA (U.S. Food and Drug Administration) and/or the OECD (Organisation for Economic Co-operation and Development) and the MHLW (Japanese Ministry of Health, Labour and Welfare). Job responsibilities include designing and conducting in vitro drug transport assays in correspondence with Protocols and Standard Operating Procedures (SOPs). Studies include inhibition… Show more Analyst for nonclinical drug transport and drug interaction studies in compliance with Good Laboratory Practice Standards (GLP) of the FDA (U.S. Food and Drug Administration) and/or the OECD (Organisation for Economic Co-operation and Development) and the MHLW (Japanese Ministry of Health, Labour and Welfare). Job responsibilities include designing and conducting in vitro drug transport assays in correspondence with Protocols and Standard Operating Procedures (SOPs). Studies include inhibition and substrate efflux, uptake, and vesicle assays utilizing various immortalized cell lines (HEK293, MDCKII, Caco-2, and Fa2N-4), the harvest of RNA from cultured human hepatocytes, RNA isolation, RNA quantification, reverse transcription, quantitative real-time polymerase chain reaction, (qPCR), and Lactate Dehydrogenase (LDH) assays. Other job responsibilities include conducting routine laboratory functions, research and development projects, perform data processing and verification, maintain accurate records and logs, and respond to in-house Quality Assurance audit reports. Proficient in the use of liquid scintillation counters, Synergy plate readers, and Microbeta2 plate readers. Show less

Kirksville, Mo

Perform NSF funded research, under the “Genetic Networks Regulating Structure and Function of the Shoot Apical Meristem” grant, investigating the evolution and expression of the Alfin gene family in Maize using a variety of wet lab and bioinformatics techniques. Wet lab techniques include tissue dissection, end-point and qRT-PCR, gel electrophoresis, RNA isolation, cDNA synthesis, genotyping, preparation of DNA for Sanger Sequencing, and confocal microscopy. Bio-informatics techniques include… Show more Perform NSF funded research, under the “Genetic Networks Regulating Structure and Function of the Shoot Apical Meristem” grant, investigating the evolution and expression of the Alfin gene family in Maize using a variety of wet lab and bioinformatics techniques. Wet lab techniques include tissue dissection, end-point and qRT-PCR, gel electrophoresis, RNA isolation, cDNA synthesis, genotyping, preparation of DNA for Sanger Sequencing, and confocal microscopy. Bio-informatics techniques include primer design, Clustal Omega, InterProScan, PhylogenyFr, RNAseq analysis utilizing the Tuxedo protocol via the Cyverse Discovery Environment and CummeRbund, DNA and protein sequence analysis using the R programming Biostrings package, and the Python programming language. Job responsibilities include conducting routine laboratory functions, designing and conducting research experiments in a molecular biology lab setting, perform data processing and assessment, and adhere to strong aseptic technique. Proficient in the use of databases including Google Scholar, PubMed, NCBI Blast, Maize GDB, and Ensemble. Show less