Christopher Culbertson Email & Phone Number

Baltimore, Md, Us

Baltimore, Maryland Area

Project: Immunity, microbiome, epigenetics, and a systems biology approach to the study of responses to vaccination with typhoid fever.-Standardized protocols for isolation of immune cells from human duodenal and terminal ileum biopsies.-Performed mass cytometry experiments and preliminary data analysis on T cell populations in intestinal biopsies and PBMCs.Project: Trial of mucosal adjuvanted H5N1 vaccine with intramuscular boost-Conducted all Flow Cytometry experiments assessing T cell responses in PBMCs.Project: Phase 1 Study of the Safety, Tolerability, and Immunogenicity of Oral Doses of CVD 1208S-122, a Prototype Attenuated Shigella flexneri 2a Live Vector Expressing Enterotoxigenic Escherichia coli antigens.-Conducted Antibody Secreting Cell (ASC) ELISpot experiments and data analysis.-Collected Antibody Lymphocyte Supernatants (ALS) for analysis by collaborators.Project: Assessing T cell responses to Modified Vaccinia Ankara-based Yellow Fever (MVA-YF) vaccine in human volunteers by Mass Cytometry (CyTOF).-Wrote standard operating procedures for assessing T-cell responses using the Helios CyTOF system and performed all experiments.-Conducted all gating and preliminary data analysis using FlowJoProject: Measurement of immune memory cell proliferation through deuterated water-labelling of DNA and measurement by Gas-Chromatography-Mass Spectroscopy (GC-MS).-Developed protocol for deuterated water labeling, DNA extraction, and derivatization of DNA for GC-MS analysis and data collection.-Designed DNA extraction protocols for use with fixed cells, allowing for intracellular staining of cells for sorting prior to GC-MS. Project: Comprehensive immunogenomic profiling after vaccination and challenge with live dengue virus.-Wrote standard operating procedures for assessing T-cell responses in dengue challenge volunteers using the Helios CyTOF system and performed all experiments.-Conducted all preliminary gating and data analysis using FlowJo.

Baltimore, Maryland Area

I've taught and tutored thousands of pre-health students as they've prepared to take the MCAT as well as other exams such as the DAT, OAT, and PCAT. My accomplishments and duties are as follows:- Fully qualified to teach all sections on the MCAT (>95th percentile in physical sciences, verbal reasoning, and biological sciences) in the classroom and extensive tutoring experience in all content areas. - Awarded Elite Instructor Status by Kaplan in January 2013 in recognition of consistently high ratings from current and former students.- Lead classroom discussions/lessons teaching content and strategy pertinent to the MCAT, DAT, OAT, and PCAT.- Experience tutoring and teaching in an online environment via Skype, Adobe Connect, and Zoom platforms.- Beyond teaching and tutoring, experience in marketing courses and products by leading information sessions, conducting MCAT content workshops, and presenting at pre-medical conferences at universities throughout the Mid-Atlantic region. - Active in mentoring new MCAT instructors throughout the region.

-Design and develop new lessons and test material specific to the 2015 MCAT exam-Create new teaching strategies for existing content-Collaborate in a virtual environment with a large team of writers and other content developers to create a consistent, high-quality end product

United States

HelpSuite faculty provide dedicated help to university students taking General Chemistry, Organic Chemistry, and Physics courses via virtual office hours and content-review sessions through email and Zoom webinars.

Baltimore, Maryland Area

As a Research Specialist with the Viral Hepatitis Research Center, I worked with Chloe Thio, MD to study immune responses to acute Hepatitis B Virus (HBV) infection in subjects who clear, control, or develop chronic infections. My contributions are as follows: -Generated replication incompetent Adenovirus-HBV (Ad-HBV) construct for use in a mouse model of acute HBV infection. -Wrote and optimized protocols for serum cytokine ELISAs and multiplex assays using the Meso Scale Diagnostics (MSD) platform. -Designed and optimized a novel AST activity assay that adapted clinical lab methods for use on microplates, resulting in reduced costs, lower required sample volumes, and faster analysis.

-Provide guidance and advice to faculty regarding payroll and billing to ensure faculty are properly rewarded for their efforts-Manage and match tutors throughout the United States with the students that would best benefit from their talents-Match outstanding faculty to marketing events that will best showcase the talents of Kaplan faculty members and the opportunities available to students through Kaplan products

Rochester, New York Area

Study calcium homeostasis and relevant signaling pathways in osteoblasts during metabolic acidosis under supervision of Dr. Nancy Krieger, PhD and coordinating with Dr. Kevin Frick, PhD.- Studied COX enzyme expression, RGS16 activity, RANKL signaling, and possible endocrine function of osteoblasts during metabolic and respiratory acidosis.- Responsible for handling all protein-based assays and biochemical assays. Experience refining existing protocols, and developing new protocols as needed.- Enhanced previous tissue and cell culture model for in vitro bone studies, enabling use of previously unreliable assays.- Developed reliable in vivo models for studying acute metabolic acidosis and acute kidney failure in mice.Under a grant from the NIH, study Vitamin D and effects on bone and renal physiology. Additionally, study pathology of nephrolithiasis and potential therapies using Genetically Hypercalciuric Stone-forming rats (GHS rats) developed by Dr. David Bushinsky, MD.- Design study protocols and schedules for determining effects of various diets and drugs in rats.- Designed new and enhanced existing protocols for sample collection and measurement via protein and biochemical assays.- Responsible for maintaining GHS colony and coordinating activities with collaborators at U of Chicago and U of Toronto.Responsible for day-to-day management of Bushinsky Lab in the Division of Nephrology at the Univeristy of Rochester School of Medicine and Dentistry- Responsible for purchasing all research supplies, reagents, assay kits, and equipment- Troubleshoot and maintain lab equipment such as spectrophotometers, blood gas and electrolyte analyzers, and imaging equipment.- Directly manage all undergraduate workers in lab- Develop relationships with industry reps to stay abreast of emerging technologies relevant to research aims.- Build and manage network of relationships amongst other Rochester labs and outside institutions.

Rochester, New York Area

UR Science Buddies is a community outreach run by the Life Sciences Learning Center at UR, which allows researchers and graduate students to volunteer at local elementary schools and lead students through various fun scientific experiments in diverse fields like nanoscience and freshwater ecology.As a team leader at French Road Elementary School, my task is to teach the lesson and elicit student questions before and after our experiments, and then direct my team of undergraduate and high school volunteers to help the children work on their experiments.Additionally, I've also been acting as a coordinator and observer with Dr Liam Casey to assess the effectiveness of Science Buddies activities. In this capacity, I record observations and collect data about the effectiveness of teaching techniques and make recommendations for modifying future activities.

Conduct background research on a variety of healthcare, pharmaceutical and biotech-related projects via journal articles, database searches, and tech manuals. Compiled data and analyzed in Excel and presented research findings with PowerPoint to recommend specific courses of action to clients in areas such as product development, research direction, and marketing strategy.

Lead patients through physical therapy exercises and using modalities such as electrostimulation and ultrasound under the supervision of physical therapists. Also responsible for organizing medical information, scheduling patients, and processing insurance information.

Cell And Molecular Pharmacology And Physiology, 3.7/4.0

Physiology Coursework: -Biochemistry -Molecular Biology -Cell and Molecular Physiology -Hearing Structure and Function -Signal.

Master'S Degree, Medical Sciences

Ba, Biological Sciences (Biochemistry, Physiology)

Activities and Societies: Sigma Chi, Slivka Residential College of Science and Engineering, Naval ROTC

Master Of Science - Ms, Cellular And Molecular Biomedical Sciences, 3.6/4.0

Coursework in the Molecular Microbiology and Immunology: -Basic Immunology -Advances in Immunology -Principles of Virology -Microbial.