Christopher Galli

Christopher Galli Email and Phone Number

Scientific advisor: pharmaceutical development and analysis, nanostructures, material science @ Cambridge, MA, US
Cambridge, MA, US
Christopher Galli's Location
Cambridge, Massachusetts, United States, United States
Christopher Galli's Contact Details
About Christopher Galli

Energetic R&D leader in pharmaceutical analysis and development, nanoparticle invention/control, and material science. Experience in biotechnology, performance materials and pharma industries. Fundamental application of physical chemistry perspective to product development, problem solving and innovation. Architect of high performing organizations. Experienced functional leader of analytical development, preformulation, material characterization, and formulation science. Accomplished in strategic business development. Experienced, inspirational project manager. Successful leader of external relationships (CMO and CRO) as both customer and provider. Helping build company strategy and direct research and development activities to achieve company goals.Technical Specialties: Method Development for chemical and physical analysis including separation science (HPLC, HPLC/MS, CE, ion chromatography, ultracentrifugation etc.), mass transport and diffusion (e.g. single and multistage dissolution w/wo dialysis), high energy solids control (e.g. nanomaterials, co-crystals, precipitation inhibition); colloid formation and stabilization; elemental analysis (e.g. ICP/OES, MS); time domain and angular light scattering for phase and particle analysis; optical and magnetic spectroscopy for surface and material characterization; calorimetry; powder, granule, and compact surface/pore distribution analysis via gas adsorption and mercury intrusion porosimetry; stress/strain analysis of solids and semi-solids via force in compression/force in tension analysis; tensile strength of solids and semisolids

Christopher Galli's Current Company Details
Jarndyce and Jarndyce, LLC

Jarndyce And Jarndyce, Llc

Scientific advisor: pharmaceutical development and analysis, nanostructures, material science
Cambridge, MA, US
Christopher Galli Work Experience Details
  • Jarndyce And Jarndyce, Llc
    Scientific Advisor: Pharmaceutical Development And Analysis, Nanostructures, Material Science
    Jarndyce And Jarndyce, Llc
    Cambridge, Ma, Us
  • Sage Therapeutics
    Director, Analytical And Preformulation Sciences
    Sage Therapeutics 2018 - 2023
    Cambridge, Ma
    Developed physiochemical measurements and biopharmaceutical in silico calculations to guide clinical formulation technology:• Rapid, material sparing, high accuracy chromatography for log P of discovery compounds• Clarification, detection, and interpolation calculations for solubility via chromatography with charged aerosol detection (to 0.3 ppb LOQ) • Food effect modeling (after Sugano) as function of dose and polymorph via Dose Number (Do), Dissolution Number (Dn), and Permeation Number (Pn )• Steady state flux measurements for transdermal, buccal, and nasal tissue
  • Cabot Corporation
    Lead Scientist
    Cabot Corporation 2010 - 2018
    Discovery and development of nanoparticles and nanodispersions with new functionalities and applications. Current efforts include novel Cabot composites for enhanced bioavaliability and interfacial hydrophobic/hydrophilic control on nano- and macroscopic scale.
  • Transform Pharmaceuticals A Johnson & Johnson Company
    Director Of Pharmaceutical And Analytical Sciences
    Transform Pharmaceuticals A Johnson & Johnson Company Jan 2006 - Jan 2010
    Lexington, Ma
    Company strategy via TPI Management TeamSite responsibility for directing J&J PRD Early Development (ED) activities : scientific and resouce planning. Steady state = 30+ compounds.Director of Pharmaceutical and Analytical Sciences : responsible for small molecule preformulation development, biopharmaceutics/bioenhancement, and product specification/analytical development. Professional development of 20+ scientists and engineersCompany, departmental, and capital budget reponsibility
  • Pfizer Global R&D
    Associate Research Fellow
    Pfizer Global R&D 2002 - 2006
    Group Leader: Method development - HPLC and all others. Chemical and physical characterization of drug substances and drug products in experimental and commercial formulations. Prepare/review scores of FDA and global submissions. Global analytical lead PAI and postapproval : Lyrica Nanoparticulate formation via fluid cavitation/shear/impact: processing, stabilization and characterization. Mass transfer parameter measurements in submicron particles.Elasticity, tensile strength and porosity of (ribbon) compacts, modeling diffusion vs. volumetric erosion API release; Kinetic stability of self-emulsifying drug delivery (SEDD) ensembles.
  • Merck Research Laboratory
    Research Fellow
    Merck Research Laboratory 1998 - 2002
    Group Leader: Method development - HPLC and all others for chemical and physical characterization of drug products in experimental and commercial formulations. Physical stabilization of nanosuspension formulation via surface active/polymeric modification.Moisture initiated deformation and phase modification of lyophilized formulations; molecular self assembly and lipophilic phase/particulate formation on stability; radical generation/oxidation via gamma radiation in polymeric packaging (EPR detection).
  • University Of North Carolina, Greensboro
    Assistant Professor, Physical Chemistry
    University Of North Carolina, Greensboro 1995 - 1998
    Built laboratory to collect time-resolved ultrasonic emission from nanosecond laser initiated reactions; photoacoustic calorimetry. These measurements quantify reaction kinetics, reaction enthalpies, and conformation dynamics. Projects include: (1) nanosecond-millisecond Na+/K+ ATPase conformational dynamics of ligand binding reactions, and (2) uni- and bimolecular deactivation mechanisms of excited electronic states in highly conjugated porphyrin arrays

Christopher Galli Skills

Analytical Chemistry Characterization Hplc Spectroscopy R&d Chemistry Drug Delivery Materials Science Organic Chemistry Research And Development Laboratory Nanomaterials Nanotechnology Technology Transfer Physical Chemistry Uv/vis Nanoparticles Science Materials High Performance Liquid Chromatography Composite Design Formulation Science

Christopher Galli Education Details

Frequently Asked Questions about Christopher Galli

What company does Christopher Galli work for?

Christopher Galli works for Jarndyce And Jarndyce, Llc

What is Christopher Galli's role at the current company?

Christopher Galli's current role is Scientific advisor: pharmaceutical development and analysis, nanostructures, material science.

What is Christopher Galli's email address?

Christopher Galli's email address is ch****@****orp.com

What schools did Christopher Galli attend?

Christopher Galli attended Harvard Business School, Yale University, University Of Pennsylvania, University Of Maryland Baltimore County (Umbc).

What skills is Christopher Galli known for?

Christopher Galli has skills like Analytical Chemistry, Characterization, Hplc, Spectroscopy, R&d, Chemistry, Drug Delivery, Materials Science, Organic Chemistry, Research And Development, Laboratory, Nanomaterials.

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