Christopher Orme Email & Phone Number

Philadelphia, PA, US

Philadelphia, Pennsylvania, United States

Philadelphia, Pennsylvania, United States

PhD Project: Structure-Activity Approaches towards a New Generation of Boron-containing Nucleoside Reverse Transcriptase Inhibitors (bNRTIs).(Advisor: Dr John Tomsho, University of the Sciences, Philadelphia, PA, USA)

Philadelphia, Pennsylvania, United States

Role involved the collection, storage and transfer of all regulated biohazard waste generated on site. Interdepartmental disposal of waste was performed in accordance with EHRS specifications and codes.

Philadelphia, Pennsylvania, United States

Teaching position involved instructing organic chemistry workshops and laboratory classes for undergraduate students as part of the department’s curriculum. The courses cover fundamental principles of organic chemistry and combines class-based learning with practical experiments

Harrogate, United Kingdom

Role involved analysis of the metabolic products from radio-labeled clinical and pre-clinical drug studies in vivo. Preparation, extraction and LC-MS analysis of animal samples were performed and reports were generated for clients following completion of the studies.

Leeds, United Kingdom

Overview:The work entails real time analysis of select football games to provide live statistical match data to some of the largest sporting organisations and media outlets in the world.Skills Developed:-Meticulous eye for detail; essential to deliver exceptionally accurate information, which is then used by third party clients-High diligence to stay.

Greater Manchester, United Kingdom

Responsibilities include: -Product and Raw Material Testing under GLP/GMP ISO 22716:2007 accredited standards; quality control, compliance adjustment, and stability studies-Formulation Development Work; research, data collection, analysis, report, and regulatory compliance-Literature Production; standard operating procedures (SOPs), certificates of.

York, United Kingdom

- Delivering practical lab session to classes of 10 – 20 BSc undergraduate students- Design and implementation of laboratory lesson briefs- Individual support to undergraduate students with course work and practical lab work- Marking and individual feedback on assessed work- Demonstration of key laboratory techniques and skills

York, United Kingdom

• Project: Late-stage Functionalisation of Agrochemical-like Scaffolds by Electrochemically-generated Free Radicals(Prof. P. O’Brien, Dr. V. Chechik, Dr. A. Parkin, in sponsorship with Syngenta)Research focused on.
• Rapidly construct a library of small, interesting agrochemical targets
• Selectively functionalise large, complex agrochemical scaffoldsSkills developed:
• Data recording – big data was recorded sensibly, backed up & stored in an easy to navigate database
• Processing and analysis – all characterisation & physical data was processed using specialist software, analysed to retrieve structural & physical meaning, & presented in a clean & consistent layout
• Use of analytical software packages: Microsoft Office, Origin, etc.

Wellington & Wairarapa, New Zealand

• Project: Synthetic Approaches Towards the Total Synthesis of (-)-TAN-2483B; a lead as a novel kinase inhibitor(Dr. Joanne E. Harvey, Victoria University of Wellington, New Zealand)Project Aims:
• Perform the total synthesis of the natural product (-)-TAN-2483B
• Explore cleaner, less wasteful and cost-effective synthetic strategies
• Scale up production and optimisation
• Probe biological activity of the natural product
• Develop analogues to investigate structure-activity relationshipSkills developed:

York, United Kingdom

• Project: The Synthesis of Two Novel Heparin Binding Agents and Study of their Biological Activity(Prof. David K. Smith, University of York, RSC Bursary)Research:This project focused on the application of nanochemistry.
• Use of tandem titration-spectroscopy as a method for probing chemical activity
• Importance of the environment (pH, temperature and pressure) on substrate performance and activity
• Application of nanochemistry to design biologically active substratesTechniques used:
• Titration
• UV/Vis Spectrometry (titration assays with heparin)

Doctor Of Philosophy - Phd, Chemistry

Researcher, Chemistry

Project Title: Late-stage Functionalisation of Drug-like Scaffolds by Electrochemically-generated Free Radicals (Prof. Peter O’Brien, Dr..

Master Of Science (Msc), Chemistry, Biological Chemistry And Medicinal Chemistry, First Class Honours

Activities and Societies: Treasurer of Edible Uni, Alcuin Environment & Ethics Support, Departmental Football, College Squash, University.

A-Levels

Activities and Societies: Inter-school Biochemistry Competitions, Dissection Society, Hockey, Table Tennis, FootballChemistry - A Biology.