Daniel Civello Email and Phone Number
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I am an accomplished leader in the biotech/healthcare industry with extensive experience applying data science and engineering methodologies to biological and clinical data and my expertise ranges from discovery research to commercial lab operations. I am interested in the entire data life-cycle, including tackling challenges such as data integration, provenance, modeling and governance, and I am committed to supporting the FAIR data principles for scientific data management and stewardship. My passion lies in creating, scaling, and leading teams that specialize in transforming data into knowledge, and I have directly applied or led teams applying the following skills:* ENGINEERING: R, Python, C, shell, numerous AWS cloud services, including Redshift, S3, Athena, etc.. many Apache Foundation tools, including Hadoop, Hive and Spark, various databases (SQL, NoSQL, graph), XML, JSON, semantic web technologies / linked data (RDF), SWE practices like code review, testing, CI/CD pipelines * DATA SCIENCE & ML: Many common frameworks including scikit-learn, Keras, Caret and Tidymodels.* BIOINFORMATICS: GATK, Bio-conductor, Nextflow & Reflow, Gene set enrichment, pathway analysis, numerous sequence databases and public data repositories (UCSC, TCGA, COSMIC, etc.)
Intervenn Biosciences
View- Website:
- intervenn.bio
- Employees:
- 52
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Bioinformatics ConsultantIntervenn BiosciencesCalifornia, United States -
Director, R And D Data EngineeringDelfi DiagnosticsCalifornia, United States -
Engineering And Data Science ConsultantPandora Bio, Inc Aug 2024 - PresentAdvisor and consultant -
Head Of EngineeringPandora Bio, Inc Feb 2023 - Aug 2024Digital biomarker discovery and precision early detection tools for student mental health -
Independent Data Science / Analytics / Engineering ConsultingSelf-Employed Jan 2023 - PresentIndependent contract and consulting for biotech/healthtech industry, specializing in:- data science and bioinformatics strategy- exploratory data analysis, dashboarding, clinical trial monitoring- data wrangling, data warehousing, data pipelines- team growth and development strategyClients include Fellow Health, Inc and Aqtual Inc.
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Director, Bioinformatics And Data EngineeringGrail, Inc. Jul 2020 - Sep 2022Menlo Park, Ca, Us- Founder and leader of the Bioinformatics Data Engineering group. Responsible for resource planning and strategy. Scaled the team to 12 individual contributors and 1 Associate Director.- Led initiative to consolidate data from GRAIL’s multi-cancer early-detection test into a data lake. -
Director, Clinical Data ScienceGrail, Inc. Aug 2018 - Jul 2020Menlo Park, Ca, Us- Implemented data vis framework in R/Shiny for GRAIL clinical trials for enrollment monitoring and exploratory analysis of clinical study participants and sites.- Co-developed a data platform to deliver validated datasets for classifier development, creating a single source of truth for study data. -
Associate Director, Clinical Data ScienceGrail, Inc. Mar 2017 - Aug 2018Menlo Park, Ca, Us- Co-developed reproducible methodology for randomization, sample selection and derived variable creation. This methodology is used consistently across all GRAIL clinical and analytical studies -
Principal Data Scientist, Research Informatics And Knowledge UtilizationCelgene Sep 2014 - Mar 2017Summit, New Jersey, Us- Established Data Engineering team to consolidate related programming activities across 3 departments.- Automated dose-response modeling for AML cancer cell lines and safety data review for CC-99282 novel compound, which eliminated the need for manual data wrangling and QC steps.- Co-developed a study curation platform based on open-source tools to create a single portal for all study data.- Co-developed a data curation platform based on open-source tools.- Automated safety data review for clinical trials for a novel compound (CC-99282).- Performed analysis on RNA-seq to explore differential gene expression between patient responders and non-responders in an early-stage therapeutic clinical trial. -
Principal Analyst, Biostatistics And Biomedical Data ComputingGenomic Health Jun 2008 - Sep 2014Redwood City, Ca, Us- Led automated data review of Oncotype DX Breast LDT, eliminating hours of manual QC steps for CLS staff.- Co-developed 12 assay metrics for Oncotype DX Prostate LDT used in troubleshooting and statistical process control.- Supported the entire study data lifecycle of Oncotype DX Prostate from early characterization to clinical validation and LDT launch. -
Staff Bioinformatics Scientist, Discovery ResearchCelera Corporation Mar 2001 - Mar 2008- Created a novel tool for identifying non-specific PCR products based on thermodynamic modeling. PCR assay success rate increased over 20%.- Co-developed a genotype-conditioned permutation test which identified and confirmed 2 genes for psoriasis risk.- Wrote NLP mining tools that consolidated pubmed evidence for hundreds of gene/disease associations of interest, reducing the number of non-significant associations of GWAS studies.- Contributed to a data pipeline for a comparative genomics study which identified thousands of mutations resulting from non-neutral evolution. -
Bioinformatics Scientist, Discovery ResearchPfizer Global Research And Development Feb 2000 - Mar 2001New York, New York, Us- Built a tool to map thousands of genetic markers to a draft genome assembly which improved the sequencing resolution for regulatory regions for genes of interest.- Created a SNP detection program from internally sequenced reads eliminating manual data processing steps.
Daniel Civello Skills
Daniel Civello Education Details
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University Of South CarolinaComputer Science Minor/Cognate
Frequently Asked Questions about Daniel Civello
What company does Daniel Civello work for?
Daniel Civello works for Intervenn Biosciences
What is Daniel Civello's role at the current company?
Daniel Civello's current role is Bioinformatics Consultant.
What is Daniel Civello's email address?
Daniel Civello's email address is ci****@****ail.com
What is Daniel Civello's direct phone number?
Daniel Civello's direct phone number is +151091*****
What schools did Daniel Civello attend?
Daniel Civello attended University Of South Carolina.
What are some of Daniel Civello's interests?
Daniel Civello has interest in Electronics, Sweepstakes, Music, Sports, Movies.
What skills is Daniel Civello known for?
Daniel Civello has skills like Bioinformatics, Genomics, Perl, Sas, Biostatistics, Molecular Biology, Lifesciences, Data Management, Molecular Diagnostics, Lims, Oncology, Life Sciences.
Who are Daniel Civello's colleagues?
Daniel Civello's colleagues are Anjo Zulaybar, Jupey Michael Sapalo, Ranjan Bhadra, Rudy Peters, Harold Viduya, Maryam Baniasad, Nelia Igcasan, Cfm.
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