Daniel Civello Email & Phone Number

California, United States

California, United States

Advisor and consultant

Digital biomarker discovery and precision early detection tools for student mental health

Independent contract and consulting for biotech/healthtech industry, specializing in:- data science and bioinformatics strategy- exploratory data analysis, dashboarding, clinical trial monitoring- data wrangling, data warehousing, data pipelines- team growth and development strategyClients include Fellow Health, Inc and Aqtual Inc.

Menlo Park, CA, US

- Founder and leader of the Bioinformatics Data Engineering group. Responsible for resource planning and strategy. Scaled the team to 12 individual contributors and 1 Associate Director.- Led initiative to consolidate data from GRAIL’s multi-cancer early-detection test into a data lake.

Menlo Park, CA, US

- Implemented data vis framework in R/Shiny for GRAIL clinical trials for enrollment monitoring and exploratory analysis of clinical study participants and sites.- Co-developed a data platform to deliver validated datasets for classifier development, creating a single source of truth for study data.

Menlo Park, CA, US

- Co-developed reproducible methodology for randomization, sample selection and derived variable creation. This methodology is used consistently across all GRAIL clinical and analytical studies

Summit, New Jersey, US

- Established Data Engineering team to consolidate related programming activities across 3 departments.- Automated dose-response modeling for AML cancer cell lines and safety data review for CC-99282 novel compound, which eliminated the need for manual data wrangling and QC steps.- Co-developed a study curation platform based on open-source tools to create.

Redwood City, CA, US

- Led automated data review of Oncotype DX Breast LDT, eliminating hours of manual QC steps for CLS staff.- Co-developed 12 assay metrics for Oncotype DX Prostate LDT used in troubleshooting and statistical process control.- Supported the entire study data lifecycle of Oncotype DX Prostate from early characterization to clinical validation and LDT launch.

- Created a novel tool for identifying non-specific PCR products based on thermodynamic modeling. PCR assay success rate increased over 20%.- Co-developed a genotype-conditioned permutation test which identified and confirmed 2 genes for psoriasis risk.- Wrote NLP mining tools that consolidated pubmed evidence for hundreds of gene/disease associations of.

New York, New York, US

- Built a tool to map thousands of genetic markers to a draft genome assembly which improved the sequencing resolution for regulatory regions for genes of interest.- Created a SNP detection program from internally sequenced reads eliminating manual data processing steps.