Corey Howe Email & Phone Number

Saskatchewan, Canada

Building ornamental bioluminescent consumer products

Saskatoon, Saskatchewan, Canada

Project: Building a consumer bioreactor to empower humans to reduce their carbon emissions•3rd employee at biotech startup•In depth tech assessments of several of biotechnologies related to carbon capture, anaerobic digestion, industrial enzymes, and renewable energy•Scientific literature and patent search •Microbiological experimental design and implementation•Rapid bioreactor prototyping, troubleshooting, and iteration •Environmental sampling for novel strain discovery•Regular results reporting and slide presentations•Lab management, Lab Safety, Ordering, responsible for hiring several employees

Saskatchewan, Canada

- Plant DNA/RNA extractions- Primer design and PCR based marker assisted screening - Plasmid cloning in E.coli - Wheat population maintenance (watering and crossing)

Greater San Diego Area

I help study things that glow to build new research tools. Bioluminescence and Biofluorescence.

Saskatoon, Sk

Studying luciferin biosynthesis pathways in fireflies using protein extraction and functional assays

Cork, Ireland

Ageria is a biotech startup that just graduated from the IndieBio Accelerator program. We are building a platform to engineer yogurt bacteria to deliver yogurts enriched with nutraceuticals. Transforming milk into medicine. We worked on developing a prototype to help slow down the aging process in humans.

Toledo, Oh

For my last semester I have independently designed a project to identify novel enzymes in fireflies. I have written and submitted a proposal to the University of Toledo Undergraduate Research Program and received funding. I will conduct experiments during the semester and present my findings in May.

Toledo, Oh

Using tissue culture, molecular biology, and bioinformatics, we are examining whether LINE-1 retrotransposons contribute to recombination-based mechanisms of telomere maintenance. Using a plasmid based rescue system we are recovering LINE-1 integration events from tumors lacking telomerase. By analyzing the sequences of both pre- and post-integration sites we can determine the integration structures of the elements, which will determine whether L1 integrates into telomere repeats in tumors without telomerase.

Minneapolis, Mn

Used cell culture techniques to develop assays for Wnt-signalling related proteins. I tested Frizzled antibodies and proteins, LGR4/5/6, RNF43, and Norrin proteins. We also designed and developed new cell lines to aid in developing new cell-based assays. I gave a final presentation of my work to the company at the end of the summer.

Toledo, Oh

I was trained in cell culture, immuno-staining, confocal microscopy, and RT-PCR techniques to study HAND2 expression in neuroblastomas in developmental biology. We differentiated cells towards different neuronal lineages and measured gene expression, in order to infer HAND2 function.

Ann Arbor, Mi

To build upon our project from 2012, using the fim system from E. coli, which flips a promoter containing segment of DNA, this project sought to utilize synthetic biology techniques to engineer the fim switch by replacing the native promoter with another promoter and creating a uni-directional switch. We demonstrate that it can function as a reliable and efficient biological transistor, or “transcriptor”. Beyond storing information and performing basic computations, the system would serve as a very useful, tightly controlled switch. I helped present our project at the iGEM regional competition and our project advanced to the championship competition.

Bowling Green, Oh

Using molecular biology and bioinformatics we sought to characterize a member of the Polyamine Uptake Transporter family of the plant pathogen Phytophthera Parasitica. The gene was codon optimized for expression in yeast and then a combination of toxicity and radioisotope uptake assays were used to assess the transport activity of this gene. Results were presented in a poster session at the 2013 Oomycete Molecular Genetics conference in Monterey, California.

Bowling Green, Oh

I was selected to be part of the BGSU SETGO summer research program. Under a mentor, we used bioinformatics to do phylogenetic analysis of several plant pathogen proteins to compare the genetic diversity of oomycetes to that of the genetic diversity across Metazoans. During this time I learned basic molecular biology techniques and got familiar with bioinformatics software. Results were presented at a poster session on campus.

Ann Arbor, Mi

Using synthetic biology techniques, we utilized the native inducible fim inversion system in E.coli. By using the unidirectional recombinase HbiF to augment the existing recombinase system that relies on the unidirectional recombinase FimE, we designed a heritable, binary memory system that can be used as a bi-directional component in more complex systems. I helped present our project at the iGEM regional and championship competitions.

Master Of Science - Ms, Data Analytics

Building proficiency in python, R, SQL, statistics, and machine learning for data science applications

Bachelor'S Degree, Cytogenetics/Genetics/Clinical Genetics Technology/Technologist

Bachelor Of Science (Bs), Bioengineering

Activities and Societies: Interdisciplinary Personalized Medicine Education Organization (IPMEO)

Associate Of Science (As), Biology

Activities and Societies: Michigan Synthetic Biology Team (MSBT), SETGO Research Internship, Vocal Jazz, Mens Chorus, Intramural Soccer.