𝗧𝗲𝗮𝗺 𝗟𝗲𝗮𝗱𝗲𝗿𝘀𝗵𝗶𝗽 • Managed a team of bioinformaticians to support cross departmental immunology, oncology, and neurology teams. • Lead integration and ingestion of a companion diagnostic pipeline for Inflammatory Bowel Disease. • Pioneered and managed team to develop a drug prioritization engine for identification of potential targets in inflammatory bowel disease (IBD) and Rheumatoid arthritis (RA).𝗦𝗶𝗻𝗴𝗹𝗲 𝗖𝗲𝗹𝗹 𝗔𝗻𝗮𝗹𝘆𝘀𝗶𝘀• Lead the cross… Show more 𝗧𝗲𝗮𝗺 𝗟𝗲𝗮𝗱𝗲𝗿𝘀𝗵𝗶𝗽 • Managed a team of bioinformaticians to support cross departmental immunology, oncology, and neurology teams. • Lead integration and ingestion of a companion diagnostic pipeline for Inflammatory Bowel Disease. • Pioneered and managed team to develop a drug prioritization engine for identification of potential targets in inflammatory bowel disease (IBD) and Rheumatoid arthritis (RA).𝗦𝗶𝗻𝗴𝗹𝗲 𝗖𝗲𝗹𝗹 𝗔𝗻𝗮𝗹𝘆𝘀𝗶𝘀• Lead the cross departmental single cell working group to facilitate ingestion of single cell sequencing methodologies and managed the 3rd party vendor platform.• Analyzed single cell sequencing datasets for immune mediated diseases and clinical trials for early discovery targets to establish proof of concept for entry into mid and late-stage drug development pipelines.𝗗𝗮𝘁𝗮 𝗠𝗮𝗻𝗮𝗴𝗲𝗺𝗲𝗻𝘁 𝗮𝗻𝗱 𝗖𝗼𝗱𝗶𝗻𝗴 • Designed and implemented data management and coding practices to ensure reproducibility and compliance.• Streamlined code, version controlled docker images, and instructional material for use by generic scientists. 𝗠𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗣𝗿𝗼𝗳𝗶𝗹𝗶𝗻𝗴• Molecular profiling analysis lead for animal models, clinical trials, and cellular assays. • Ingested and analyzed single cell sequencing data for immunology, neurology, virology, and oncology. Show less

𝗠𝗮𝗻𝗮𝗴𝗲𝗿 • Managed a direct report, a post doctoral fellow, and 4 interns to support areas of immunology, oncology, neuro-immunology, and chemistry. 𝗠𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗣𝗿𝗼𝗳𝗶𝗹𝗶𝗻𝗴• Molecular profiling analysis lead for animal models, clinical trials, and cellular assays. • Led technical portion of the high dimensional flow (HDFlow) cytometry working group. Saved cost of ~$500k by changing vendors and producing in house analysis methodology. • Pipeline… Show more 𝗠𝗮𝗻𝗮𝗴𝗲𝗿 • Managed a direct report, a post doctoral fellow, and 4 interns to support areas of immunology, oncology, neuro-immunology, and chemistry. 𝗠𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗣𝗿𝗼𝗳𝗶𝗹𝗶𝗻𝗴• Molecular profiling analysis lead for animal models, clinical trials, and cellular assays. • Led technical portion of the high dimensional flow (HDFlow) cytometry working group. Saved cost of ~$500k by changing vendors and producing in house analysis methodology. • Pipeline development for ATACSeq, proteomics, and methylation. • Developed proximity labeling pipeline for proteomics. Published work in high profile journals Science and Nature’s Chemical Biology.𝗦𝗶𝗻𝗴𝗹𝗲 𝗖𝗲𝗹𝗹 𝗔𝗻𝗮𝗹𝘆𝘀𝗶𝘀• Created a single cell analysis pipeline applicable to large scale sequencing studies (300+ samples).• Integrated single cell sequencing, bulk sequencing, and proximity labeling platform analyses to identify molecular profiles of interacting cells. 𝗗𝗮𝘁𝗮 𝗠𝗮𝗻𝗮𝗴𝗲𝗺𝗲𝗻𝘁 𝗮𝗻𝗱 𝗖𝗼𝗱𝗶𝗻𝗴 𝗦𝗽𝗲𝗰𝗶𝗮𝗹𝗶𝘀𝘁 • Designed code to be reproducible, sufficiently commented, and usable by those without significant coding experience. • Created version controlled docker images, and instructional material for use by generic scientists. Show less

𝗘𝗽𝗶𝗴𝗲𝗻𝗼𝗺𝗶𝗰𝘀• Application of methylation profiling and SNP analysis to the study of respiratory disorders such as asthma and allergy. • Lectured and taught Omics dataset analyses, how to design a proper study, and how to process and analyze next-generation sequencing data.

𝗣𝗿𝗼𝗷𝗲𝗰𝘁 𝗖𝗼𝗼𝗿𝗱𝗶𝗻𝗮𝘁𝗶𝗼𝗻• Project coordination and facilitation of genome wide association studies in Meniere's disease and otosclerosis.𝗠𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗣𝗿𝗼𝗳𝗶𝗹𝗶𝗻𝗴• Generated the first in-house computational pipeline for next generation sequencing at the company• Developed computational SNP analysis pipeline for genome wide association studies.

𝗘𝘅𝗽𝗲𝗿𝗶𝗺𝗲𝗻𝘁𝗮𝗹 𝗗𝗲𝘀𝗶𝗴𝗻• Expertise in experimental design of mouse and preclinical studies.