Craig Carson Email & Phone Number

Raleigh, Nc, Us

Rtp, North Carolina

I am currently in a customer facing role to obtain customers for our Contract Development and manufacturing services. My job is to engage potential clients, assess their needs and develop a plan to help them fulfill those goals. Additionally I am creating and editing workflows with Project Managers, Quality Assurance personnel, Quality Control personnel, Manufacturing personnel, and R&D scientists to streamline our CDMO business and procedures.

Research Triangle Park, Nc

Developing ELISA tests in a CRO and CMO environment. We develop ELISA assays, along with additional assays, in a GLP and GMP environment for clients with an eye towards FDA approval.

Durham County, North Carolina, United States

In this 1 year contract role I performed early stage development of a methylation specific diagnostic test for the triaging of cervical cancer patients.

I am a consultant that specializes in biotechnology startup companies. I have had a broad range of experiences in tech transfer from an academic to a biotech setting, setting up laboratories, defining work flows, phase 1 clinical trials, and in the decommissioning laboratories.Data interpretationDecommissioning of laboratorySelling and storing of laboratory equipment

Morrisville, Nc

BioFluidica is a company that uses microfluidic devices to deliver on the promise of the liquid biopsy. My role is to run patient samples through our laboratory and deliver better data for doctors making treatment decisions for cancer patients. Another aspect of my position is business development and identification of potential collaborators.

Chapel Hill North Carolina

Studied methods to identify and treat melanoma. This has led to the identification of multiple biomarkers, a therapeutic target for melanoma treatments, a diagnostic test, and clinical trials for stage 4 melanoma patients.Scientific ResponsibilitiesIdentification and analysis of potential Melanoma Biomarkers and therapeutic targetsIdentification of potential therapeutic target from epigenetic (Methylation) studyAnalysis of Immunohistochemically stained samples In vivo analysis of potential target (Single Cell Motility, Proliferation, and Anchorage Independent assays)Utilization shRNA Lentiviral constructsIdentification and employment of potential inhibitorsInitiation and management of collaborationsUse Genetically Engineered Mice (GEMs) to evaluate potential melanoma therapiesAnalysis of Melanoma Cell Lines and Human SamplesAnalysis of Nex Gen DataMethylation ArraysCGH ArraysExpression arraysGene signatures that predict G1 and G2 Checkpoint integrity and predict future melanoma metastasisGene signatures that predict genomic stability of melanoma cell linesAnalysis of Radiation SensitivityDetermining and analyzing NRAS, BRAF statusUsing CGH data to Characterize Genomic InstabilityAnalyzing G1, G2 checkpoint integrity Management ResponsibilitiesWriting of GrantsWriting papersTraining Medical Students in Molecular Biology TechniquesIdentifying Questions to be answeredDesigning Experiments

This was a 4 month contract position to devise methods to present data for two final reports. The data that was reported was both expression array and metabolomic results of drug studies.Management Responsibilities Analysis of microarray data from an alcohol study in rats Analysis of metabolomic data from the above study Devising a coherent method to present metabolomic and microarray simultaneously Production of a final report of metabolomic and microarray data Production of figures and assisting in writing peer reviewed paper(s) Software Used: Partek, Rosetta Resolver, GENNMapp, Pathway Miner, Osprey, Cytoscape

Morrisville North Carolina

I was hired to design and build a facility to handle outside samples to run through a proprietary cell based assay to determine changes in the activity of multiple transcriptional elements.Scientific Responsibilities Learn and perform the proprietary technologies used for the Detection Facility Analyze data generated by the FACTORIAL™ process Assess the viability of automating Attagene’s Work Flow Determine effective data acquisition and storage methods for Detection Facility dataManagement Responsibilities Identification and presentation of automation options for Detection Facility Performed a cost analysis for the Detection Facility Create a Chain of Custody for every sample/chemical that enters the Facility Devise options to upgrade data acquisition capacity Identified and wrote Standard Operating Procedures (SOPs) Write Quality Management Plans for contracts and grants for ToxCast Grant Production of methods to process and analyze data from proprietary processes

Vector Research is a division of Liggett Meyer that is tasked with developing a safer cigarette. It is the goal of Vector Research to apply cutting edge molecular biology techniques to develop methods to identify safer cigarettes.Scientific ResponsibilitiesPlan and utilize a cell based assay to assess cigarette smoke damageInterpret microarray data of smoke exposed human lung cellsIdentify and assess potential software for mining microarray data (using Spotfire, Genespring, Pathway Assist, GeneMapp, MIDAS, TMEV, Vector PathBlazer, ArrayAssist) Utilize RNAi to knock out genes of interest in a cell culture systemIdentify and procure antibodies to assess RNAiQPCR of specific genes of interest to validate microarray dataPerform differential display analysis on cells exposed to smokeELISA analysis for cytokines and PGE2 levelsManagement ResponsibilitiesEquip and organize new laboratoriesSummarize laboratory results in weekly reportsIdentify diagnostic proteins/mechanisms that indicate the presence of lung cancerDrive potential avenues of research through written reviews of topics of interest

Research Triangle Park North Carolina

Ribonomics is a company initiated with the intellectual property I developed at Duke University. A cell based assay is utilized to identify important mRNAs in specific biological processes and help interpret expression array data.Scientific ResponsibilitiesDesign peptides and produced antibodies to RNA binding proteinsScreen the resultant antibodies for reactivityUtilize these antibodies to precipitate mRNA binding proteins and enable Ribonomics’ proprietary technologyProduce cDNA probes from microarrays (using Traditional incorporation, Amino-allyl coupling, aRNA; Tyramide Signal Amplification and Cy3 / Cy5 and Alexa dye probes)Scan microarrays with an Axon 4000B scanner and GenePixAnalyzed results with GenespringConfirm array results with Real-Time PCR and Northern analysis Initiate RNAi in a neuronal development tissue culture modelManagement ResponsibilitiesInterview, hire, supervise, and train scientific and business personnelDesign, equip, and manage a tissue culture facility and new laboratoriesDirect Drug Discovery tools via RNA binding protein pathways

Phd, Microbiology / Genetics

Bs, Biotechnology