Dana Danger Email & Phone Number

Durham, Nc

Designed, conducted, and analyzed investigative and clinical diagnostic experiments to meet sponsor needs. Progressed drug development projects through assay development and HPLC/MS/MS analysis of enzyme assays, metabolic stability, plasma protein binding, and pharmacokinetic and toxicokinetic study samples. Initiated and completed a Fireplex flow cytometry project for a client. Initiated and performed qPCR experiments to quantitate COVID19 in plasma samples. Interacted with sponsors to complete studies, provide data, and write reports within defined timelines. Validated analytical methods, conducted sample analysis for assigned phases of clinical diagnostic work, ensured procedures were designed and followed for compliance, including assurance. Documented all experimental data (including observations of unanticipated responses) and accurately recorded and verified results. Reported results and verified and approved final reports. Served as lead contact for a customer-based program within the company, coordinating kit supply and shipping, directing sample processing, analyzing data, sending reports, and handling communications with the customer.

Research Triangle Park, Nc

Primary support resource for cellular and molecular biology for enteroendocrine research from 2008-2015. Designed, generated, and validated reagents for target expression, and developed and performed assays to progress drug discovery. Performed expression analysis experiments to support animal studies and target validation. Prior GSK experience was in Discovery Research in therapeutic areas including diabetes, obesity, and virology targets in HIV, HCV, and HSV. Designed, generated, and validated reagents for target expression. Validation work includes SDS-PAGE, Western blots, in vitro assays, and protein purification using the AKTA system.

Raleigh, Nc

Research centered around ferritin. Performed cloning, mutagenesis, expression, and protein purification work to supply proteins for laboratory studies.

Raleigh, Nc

Research on isoforms of glutathione-S-transferase in mouse.Biochem J. 1992 Dec 1;288 ( Pt 2):361-7.Photoaffinity labelling of steroid-hormone-binding glutathione S-transferases with [3H]methyltrienolone. Inhibition of steroid-binding activity by the anticarcinogen indole-3-carbinol.Danger DP, Baldwin WS, LeBlanc GA.

Master'S Degree, Toxicology

Minor in biochemistry

Bachelor'S Degree, Biochemistry

Activities and Societies: Teaching Assistant for undergraduate biochemistry course. Residential Scholars Program