Daniel Beacham Email & Phone Number

Eugene, Oregon

I develop cell-based imaging and biochemical assays for basic sciences research and drug discovery.Hired Staff Scientist Jun 2006, promoted Senior Staff Scientist Apr 2008Publications:TRPC6 channel translocation into phagosomal membrane augments phagosomal function.Proceedings of the National Academy of Sciences. 2015 Nov; vol 112(145)Optical measurements of excitability with FluoVolt™ Membrane Potential Dye.J Pharmacol Toxicol Methods. 2015 Jul-Aug;74:40Cell-based potassium ion channel screening using the FluxOR assay. J Biomol Screen. 2010 Apr;15(4):441-6. Disease-causing mutations in the cystic fibrosis transmembrane conductance regulator determine the functional responses of alveolar macrophages. J Biol Chem. 2009 Dec 18;284(51):35926-38.A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel. Analytical Biochemistry. 2009 Nov 1;394(1):30-8.Evaluation of granulocyte phagocytic activity using pHrodo dye, a novel fluorogenic pH indicator.FASEB J. Apr 2008; 22: 569.Patentshttp://patents.justia.com/inventor/daniel-beacham

Seattle, Washington

William Catterall labStructure/function of voltage gated sodium ion channels and CNS excitabilityPublicationsFunctional properties and differential neuromodulation of NaV1.6 channelsMolecular and Cellular Neuroscience 2008 Aug;38(4):607-15Regulation of Nav1.2 Channels by Brain-derived Neurotrophic Factor, TrkB, and Associated Fyn Kinase Journal of Neuroscience 2007 Oct 24;27(43):11543-51Sites and Molecular Mechanisms of Modulation of Nav1.2 Channels by Fyn Tyrosine Kinase Journal of Neuroscience 2007 Oct 24;27(43):11533-42

London, Uk

Martin Koltzenburg labElectrophysiological and imaging studies of sensory neuron thermal excitability and phenotypePublicationsThe functional expression of mu opioid receptors on sensory neurons is developmentally regulated; morphine analgesia is less selective in the neonate. Pain. 2004 Sep;111(1-2):38-50Cold-sensitive, menthol-insensitive neurons in the murine sympathetic nervous system. Neuroreport. 2004 Jun 28;15(9):1399-403

Portland, Oregon

Edwin McCleskey labElectrophysiology and molecular biology of pain sensor neuronsThesis: Cellular and Molecular Mechanisms of Pain Control by OpiatesPublicationsQuantitative single-cell differences in mu-opioid receptor mRNA distinguish myelinated and unmyelinated nociceptors. J Neurosci. 2003 Jan 1;23(1):34-42Mu and delta opioids but not kappa opioid inhibit voltage-activated Ba2+ currents in neuronal F-11 cells. Brain Res. 1997 Aug 22;766(1-2):66-71

Doctor Of Philosophy (Ph.D.), Neuroscience

Activities and Societies: Vice President, Graduate Student Organization 1998-2000

Bachelor Of Science (B.S.), Chemistry

Education record

Education record

Education record