Danielle Langley Email & Phone Number

Oxford, England, United Kingdom

Experience in early phases of small molecule drug discovery including establishing biochemical screening assays, running high-throughput screens and characterizing small molecule mechanism-of-action.

Performing analysis of biological samples in assay development, assay validation and sample analysis studies.Performing analysis in accordance with the most current study protocols, analytical procedures and standard operating procedures (SOPs).Completing experiments and data tabulation in a timely, efficient and tidy manner.Trained to GxP regulatory requirements (including GMP, GCP, GLP and GCLP)Assisting in support functions (e.g. metrology, cleaning, sample receipt, data checking, etc…) required to ensure that studies are performed in a regulatory compliant manner.Completing validation of software and qualification of equipment.Ensure that all work is performed in compliance with Health and Safety policies and current legislation.Attended training courses.Writing and reviewing company SOPs, reports and analytical procedures.Participating in laboratory and other in house meetings.Participating in internal, sponsor and regulatory audits.Key Skills:Enzyme Linked Immunosorbent Assays (ELISAs) Flow Cytometry - Intra and extracellular staining, main focus on T-Cell subsets and immunophenotyping. Experience in Beckman Coulter FC500 and BD FACSCanto II.Cell culture - HUT 78 cells and NAB2 11 cells (suspension cell lines)Cell based assaysNeutralising antibody assaysPBMC preparation - for both FACs and Western Blotting experiments.SDS-PAGE and Western Blotting assays.Luminex assaysECL assaysValidation and optimisation of new assays.Use of specific software including: Softmax Pro 5.2, Ascent, TL120, flow cytometry software (MXP, CXP, and FACS Diva).Software validation (TL120)Mentoring new scientistsTraining other members of staffWorking independently and as part of a team

Bachelor Of Science; Bsc) Honours, Biomedical Sciences

with upper second class honours; Dissertation: A year long laboratory based project entitled The Thermal Stability of the kCSA Potassium.

Education record

Biology (A), Maths (A) Chemistry (B); Dance (D) General Studies (A) Critical Thinking (C)