David Brown Email & Phone Number

London, GB

Strategic contribution:Led FabricNano’s successful investigation of BVMO enzyme immobilisation in partnership with Ginkgo. Design and Product Management of an automated Data Analysis pipeline for commercially sold “Predictive Immobilisation Plates”.Product Management of analytical testing strategy for marketed commercial laundry detergent to capture toxins.

Shoreditch, England, United Kingdom

Strategic contribution:Designed and Product Managed a comprehensive digital tracking system for cell biology.Integrated clonal cell line isolation, microscopy images, population doubling times, qPCR, and RNA-seq.Wrote prototype scripts myself and worked with expert programmers to add the necessary features to Benchling Lab Notebook and Inventory management.

San Francisco Bay Area

Strategic contribution:Drove adoption of Quartzy as our Lab Inventory (LIMS)Drove adoption of Benchling as our Electronic Lab Notebook (ELN)Worked with Serotiny to express and test combinatorial protein designs of modular functional domainsAccelerated cloning for mammalian expression and cell line creation by adopting the Mammalian Tool Kit system (a.

Oxford, United Kingdom

Utilized a multiplexed Cas9 targeting strategy to generate double knockout mouse ESCs Quantified gene expression changes in nuclear-RNA from conditional knockout mouse ESCs spiked with a known number of Drosophila cells Generated and analysed calibrated native ChIP-seq data from a panel of rescue cell lines with and without drug treatment

Oxford

Designed, produced and purified novel high performance antibodies for immunofluorescence imaging and ChIP-seq.Conducted live cell imaging and super-resolution experiments. Designed and cloned a variety of plasmids for protein purification from bacteria and insect cells, and for stable expression in mouse ES cells.Generated, screened and maintained stable.

Slough, United Kingdom

During the university holidays, I worked in the lab at UCB, where I successfully identified antibodies which could stimulate and antagonize signalling by Programmed cell death 1 (PD1) in vitro. PD1 is a receptor expressed on the surface of T-cells which can down-regulate immune responses to promote tolerance, as opposed to activation of the immune system.

Doctor Of Philosophy (Ph.D.), Chromosome And Developmental Biology

Activities and Societies: My PhD in the Klose Lab was funded by the Wellcome Trust Studentship ProgramMy viva was examined by Professor.

Masters, Molecular Biochemistry, 2:1

Activities and Societies: OUSSCFor my first three years as a Biochemistry Student at Exeter College, I attended weekly tutorials with.

High School