Diego Escalante Email and Phone Number
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• Chemical engineer and structural biology expert with 8+ years of experience in software development, predictive analytics, and data-driven rational design of small molecule drug inhibitors.• Demonstrated abilities in the automated analysis of big data systems through machine learning, neural networks, and artificial intelligence to optimize bio-catalyzed chemical synthesis. • Interdisciplinary collaborator with experience working on cross functional teams with both academic and industry team members including public health specialists, engineers, and investors.• Experienced in written and oral communication to various audiences through 12 publications with 8 in peer-reviewed journals and 8 oral presentations at national conferences.• 15 years of experience in programming & data engineering languages: Java, Bash, R, Python, C++, SQL, MATLAB.• 8 years of experience conducting computational biophysical research, developing computational infrastructure, and deploying computational workflows for use by the general public.
Bio-Techne
View- Website:
- bio-techne.com
- Employees:
- 1993
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Structural BiologistBio-Techne Oct 2022 - PresentMinneapolis, Minnesota, United States
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Postdoctoral Research AssociateUniversity Of Minnesota Sep 2019 - May 2022Minneapolis, Minnesota, United States• Elucidated the interactions that control the stability of inhibitor binding at the interface of the highly anisotropic surface of M. tuberculosis receptors and commercially available antibiotics. • Designed and implemented highly scalable algorithms to automate and streamline high-throughput predictions of tuberculosis inhibitors. • Conducted statistical analysis of big data sets through machine learning and neural network algorithms to design small molecule inhibitors.• Designed, tested, and validated computational protocols to develop new methodologies that increase the signal to noise ratio in the calculation of binding affinities. • Built homology models for several protein receptors related to cancer, HIV, tuberculosis, and Sars-CoV-2 to understand key binding interactions and rationally design more potent small molecule inhibitors. -
Graduate Research AssistantUniversity Of Minnesota Sep 2013 - Jul 2019• Studied the thermodynamic properties of biodegradative chemical reactions and surface interactions using statistical mechanics, molecular mechanics, and quantum simulations.• Developed algorithms to automate the 3D visualization of tunnels inside enzymes via mesh representation and speed up the calculation of biodegradation predictions.• Designed, developed, and maintained a SQL-driven website to provide access to over 10,000 predicted chemical reactions.• Collaborated in the elucidation of enzyme structures via X-ray crystallography to properly model the surface interactions of encapsulated enzymes inside silica gel microbeads and improve the rate of biodegradation.• Collaborated in the characterization of silica gel microbead surface properties via electron microscopy to improve the distribution of media properties and enhance the biodegradation capabilities of encapsulated enzymes.
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Principal InstructorUniversity Of Minnesota Jun 2017 - May 2018Course: Introduction to Engineering Thermodynamics• Developed and taught syllabus implementing interactive learning for 70 junior level undergraduates.
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Teaching AssistantUniversity Of Minnesota Sep 2013 - Dec 2017Courses: Engineering Modeling, Modern Thermodynamics, Introduction to Engineering Thermodynamics• Prepared discussion material and in-class activities focusing on lecture material for 20-30 senior level undergraduate and first year graduate students.
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Junior Research ScientistUniversity Of Minnesota Sep 2012 - Aug 2013• Developed a system to rank chemicals found in hydraulic fracturing waters.• Model ligand-protein interactions to determine the probability that chemicals found in hydraulic fracturing waters can biodegrade.• Designed algorithms to generate all possible isomer structures of a chemical molecule.• Work in an interdisciplinary group environment including mechanical engineering, biochemistry, and public health experts.
Diego Escalante Skills
Diego Escalante Education Details
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Mechanical Engineering
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Chemical Engineering
Frequently Asked Questions about Diego Escalante
What company does Diego Escalante work for?
Diego Escalante works for Bio-Techne
What is Diego Escalante's role at the current company?
Diego Escalante's current role is Structural Bioengineer.
What is Diego Escalante's email address?
Diego Escalante's email address is de****@****umn.edu
What schools did Diego Escalante attend?
Diego Escalante attended University Of Minnesota, University Of Minnesota.
What skills is Diego Escalante known for?
Diego Escalante has skills like Leadership, Computational Biology, Research And Development, University Teaching, Drug Design, Computational Modeling, Data Science, Electron Microscopy, Statistical Analysis, Predictive Modeling, Numerical Analysis, Protein Structure.
Who are Diego Escalante's colleagues?
Diego Escalante's colleagues are Tshililo Mphagi, Parth Sadriya, Walter Baker, Paula Mckeogh, Angelina Hang, Daniel Zeleke, Will Carlen.
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