Divya Subramonian Phd Email & Phone Number

United States

United States

Eugene, Oregon, United States

- Manage the Office of Translational Science, an initiative established in April 2022, with a core mission of transforming research findings from the lab, clinic into practical strategies that enhance the health and well-being of individuals and the public.- Foster interdisciplinary collaborations, organized partnerships, and networking opportunities among diverse programs and stakeholders, including investigators, patients, and the community, to facilitate the translation of scientific discoveries into tangible outcomes.- Develop and implement strategies to promote and support translational initiatives, ensuring effective communication and knowledge exchange between research teams, clinicians, industry partners, and community organizations.- Evaluate and measure the impact and outcomes of translational initiatives, collecting and analyzing data to assess the effectiveness of strategies and identify opportunities for improvement.- Stay abreast of advancements and trends in the field of translational science, incorporating emerging methodologies and best practices into the operations of the Office, and leveraging innovative technologies to accelerate the translation of research into practical solutions.

Eugene, Oregon, United States

- Manage internal grant opportunities and limited submissions programs for external grant opportunities, ensuring seamless timelines for submission, review, and selection processes.- Collaborate closely with Foundation Relations to identify and explore private foundation funding opportunities that align with the organization's objectives.- Demonstrate expertise in efficiently collecting and organizing ROI data for awarded grants, enabling accurate reporting on proposals and awards.-Generate regular reports on proposal and award metrics and tracking outcomes of initiatives within the Research and Development function.-Take charge of institutionally-funded seed grants, implementing effective strategies to define and consistently capture new metrics that gauge the success and impact of these initiatives.

Eugene, Oregon, United States

San Diego, California, United States

Greater San Diego Area

• Lead scientist in a medical device product development team for a fluorescent based IVD assay to detect unbound bilirubin levels in neonates.• Contributed in trouble shooting and standardizing the assay along with the execution of high throughput cartridge manufacturing for clinical analytical studies. • Accountable for writing detailed technical SOPs and work instructions for FDA-510K, ISO13485.

Greater San Diego Area

• Excelled in the use of Incucyte Zoom that has state of the art technology to document cell proliferation, apoptosis, migration and differentiation of the neuroblastoma preclinical models when treated with various small molecules.• Identified the key regulators that control neuroblastoma by treating tumor cell lines with therapeutic drugs like Retinoic acid, Regorafenib and Vandetanib independently or in combination, using Western Blot analysis. Collaborated with proteomics group and statisticians for executing and analyzing Reverse Phase Protein Array (RPPA) data.• Implemented CRISPR/Cas9 technology to knockout UBE4B to understand the role of UBE4B in neuroblastoma differentiation.

Houston, Texas Area

• Investigated the protein expression profile in various neuroblastoma cells treated with several pre-clinical drugs using high throughput biochemical assays and immunoassays.• Analyzed large volumes of data from reverse phase protein analysis.

Greater Detroit Area

Project 1: Identifying biomarkers during breast cancer metastasis• Efficiently mapped the epitope region of SUMO-1 and SUMO-2/3 against their respective monoclonal antibodies using several rounds of molecular cloning, peptide purification and Immunoblot.• Designed and developed a novel technique called SUMO ePItope Peptide Elution (SUMO-e-PIPE) involving SILAC labeling, immunoprecipitation, Western blot and LC-MS to identify biomarkers in breast cancer metastasis.• Evaluated huge data sets from mass spectrometry analysis and created protein interaction maps using STRING software.• Resolved a network of genes and found to be involved in cell migration, stress response and glycolysis, implying that dysregulation of SUMOylation leads to cancer metastasis and tumorigenesis.• Executed 3D collagen cell migration assay to enforce that SUMO-2/3 is essential for migration and metastasis.• Authored and published two peer reviewed research articles and several poster presentations in international conferences.Project 2: Essential roles of SUMO in nuclear transport and cell division • Spotted and documented annulate lamellae pore complex primary neurons and smooth muscle cells using immunofluorescence microscopy.• Designed and engineered artificial Nuf2-SUMO-1/2 fusion constructs of different lengths by sub-cloning DNA fragments and site-directed mutagenesis.• Discovered that polymeric SUMO-2/3 chain modification of Nuf2 is required for CENP-E localization to kinetochore and chromosome alignment to metaphase plates by overexpression, knock down and immunofluorescence assays.• Employed biochemical techniques like in vitro binding assay and co-immunoprecipitation assay to claim that Nuf2 binds to CENP-E with more affinity when it is fused with SUMO.

Clinical Study Implementation And Management

Doctor Of Philosophy (Ph.D.), Cell/Cellular And Molecular Biology

Bachelor’S Degree, Industrial Biotechnology, 8.48/10