David Knight

David Knight Email and Phone Number

Consultant @ Leeds, GB
Leeds, GB
David Knight's Location
Santa Fe, New Mexico, United States, United States
David Knight's Contact Details

David Knight work email

David Knight personal email

n/a

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About David Knight

My Major Achievements are:-• Taken responsibility for the assay development, cloning and protein engineering of a lightly resourced novel antibody project that focused on a novel biological entity allowing for its assessment as a potential new immunomodulatory therapeutic agent. Successfully cloned, humanised and expressed a wide variety of potential therapeutic antibodies including FDA approved Cimzia® that is currently used for the treatment of rheumatoid arthritis and FDA approved Reslizumab® that causes a significant reduction in the frequency of asthma compared with those receiving placebo.• One of two scientists employed by a fast growing start up biotechnology company that focused on the rapid identification of novel soluble domains. My work involved using high throughput combinatorial domain hunting technology to aid the discovery and crystallography of various therapeutic agents. In this business development, role I created methods that made the company commercially viable and instigated a major collaborative project that resulted in the company having upwards of 78 employees.• Mentored Postdoctoral scientists and contributed many biological aspects to several small multidisciplinary teams. Completed antibody library platforn transfers to key phamceutical and biotechnology companies.• Promptly purified, crystallised, determined and reported the initial structure of a potential neurologically important molecule (GABARAP) permitting further rational functional analysis via protein engineering.• Effectively applied a range of expression technologies to target molecules using mammalian tissue culture, yeast cell culture and microbial systems, also presented data at board level of Europes largest biotechnology company at the time (Celltech Therapeutics).• Acquired a strong commercial awareness of the drug discovery business and was promoted during my time with my employer for contributions to challenging programmes. Areas of interest :- Phage display, Antibody engineering, Molecular biology, Protein expression & purificationPharmaceutical Targets, Science writing, Science & Math teaching, X-ray crystallography, Web design, Computer programming and Karate.

David Knight's Current Company Details
AntibodyWorld

Antibodyworld

Consultant
Leeds, GB
David Knight Work Experience Details
  • Antibodyworld
    Consultant
    Antibodyworld
    Leeds, Gb

David Knight Skills

Molecular Biology Biotechnology Protein Expression Life Sciences Protein Purification Purification Science Biochemistry X Ray Crystallography Drug Discovery Laboratory Protein Chemistry Pharmaceutical Industry Teaching Antibodies Web Development Science Journalism Drug Development Elisa Nmr Protein Structure Bacterial Cell Culture Antibody Engineering Instructional Design Mathematics Cell Biology Cell Culture Immunology Biopharmaceuticals Mammalian Cell Culture Nmr Spectroscopy Web Design Ngs Synthetic Biology Real Time Polymerase Chain Reaction Dna Sequencing Automation Phage Display Karate

Frequently Asked Questions about David Knight

What company does David Knight work for?

David Knight works for Antibodyworld

What is David Knight's role at the current company?

David Knight's current role is Consultant.

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What is David Knight's direct phone number?

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What skills is David Knight known for?

David Knight has skills like Molecular Biology, Biotechnology, Protein Expression, Life Sciences, Protein Purification, Purification, Science, Biochemistry, X Ray Crystallography, Drug Discovery, Laboratory, Protein Chemistry.

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