René Jørgensen Email & Phone Number

Selected peer-reviewed publications1. High-resolution structure of native toxin A from Clostridioides difficile. Aminzadeh, A., Larsen, C. E., Boesen, T., and Jørgensen, R. 2021 EMBO reports DOI: 0.15252/ embr.202153597 (I.F. = 8.8) 2. Therapeutic Drug Monitoring of Isavuconazole: Serum Concentration Variability and Success Rates for Reaching Target in Comparison with Voriconazole. Risum, R., Vestergaard M., Weinreich, U. M., Helleberg, M., Vissing N. H., and Jørgensen, R. 2021 Antibiotics 10, 487 (I.F. = 4.6)3. Systematic Evaluation of Parameters Important for Production of Native Toxin A and Toxin B from c. difficile. Aminzadeh, A. and Jørgensen R. 2021 Toxins 13, 240. (I.F. = 4.1) 4. Detoxification of toxin A and toxin B by copper ion-catalyzed oxidation in production of a toxoid-based vaccine against Clostridioides difficile. Aminzadeh, A., Tiwari M. B., Mustapha S. S. M., Navarrete S. J., Henriksen A. B., Møller I. M., Krogfelt K. A., Bjerrum M. J., Jørgensen R. 2020 Free Radical Biology & Medicine. Nov 20;160:433-446. (I.F. = 7.4) 5. Emerging Terbinafine Resistance in Trichophyton. Saunte, D. M. L., Hare, R. K., Jørgensen, K. M., Jørgensen, R., Deleuran, M., Zachariae, C. O., Thomsen, S. F., Bjørnskov-Halkier, L., Kofoed, K. & Arendrup, M. C. 2019 Antimicrobial Agents and Chemotherapy Sep 23;63(10) (I.F. = 4.9)6. Biophysical comparison of diphtheria and tetanus toxins with the formaldehyde-detoxified toxoids, the main components of diphtheria and tetanus vaccines. Alsarraf H, Dedic E., Bjerrum M., Østergaard O., Kristensen M.P., Petersen J.W.,Jørgensen R., 2017 Virulence Apr 21:1-10. (I.F. = 5.4)7. Determination of isavuconazole in human plasma using high-performance liquid chromatography with fluorescence detection. Jørgensen R., Astvad K., Andersen S.R., Arendrup M.C.. 2017 mSphere May 10;2(3). pii:e00098-17. (I.F. = 4.3)8. A Novel Fic Protein from Clostridium difficile Reveals an Inhibitory Motif-Independent Adenylylation/AMPylation Mechanism. Dedic E, Alsarraf H, Welner DH, Østergaard O, Klychnikov OI, Hensbergen PJ, Corver J, van Leeuwen HC, Jørgensen R. 2016 Journal of Biological Chemistry Apr 13. pii: jbc.M115.705491 (I.F. = 4.2)9. Biophysical characterization and activity of lymphostatin, a multifunctional virulence factor of attaching & effacing Escherichia coli. Cassady-Cain RL, Blackburn EA, Alsarraf H, Dedic E, Bease A, Böttcher B, Jørgensen R, Wear M and Stevens MP. 2016 Journal of Biological Chemistry Mar 11;291(11):5803-16 (I.F. = 4.2)

Listed skills include Protein Expression, Biochemistry, Protein Chemistry, Molecular Biology, and 18 others.