Louise Birch
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Louise Birch Email & Phone Number

Deputy Director at Sygnature Discovery
Location: Nuneaton, England, United Kingdom 9 work roles 3 schools
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Current company
Role
Deputy Director
Location
Nuneaton, England, United Kingdom
Company size

Who is Louise Birch? Overview

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Louise Birch is listed as Deputy Director at Sygnature Discovery, a company with 671 employees, based in Nuneaton, England, United Kingdom. AeroLeads shows a matched LinkedIn profile for Louise Birch.

Louise Birch previously worked as Associate Director at Sygnature Discovery and Principal Scientist (Computational Chemistry) at Sygnature Discovery. Louise Birch holds Doctor Of Philosophy (Phd), Chemistry from University Of Cambridge.

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Sygnature Discovery

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Profile bio

About Louise Birch

• Expert computational chemist with extensive experience in the pharmaceutical industry and proven project leadership skills. • Instrumental in providing computational drive to programmes targeting enzymes, ion channels and GPCRs in disease areas including Alzheimer’s, Parkinson’s, schizophrenia, diabetes and oncology.• Design of compounds with specific tissue distribution and/or modes of delivery (e.g. CNS, inhaled).• Excellent communication skills when interacting within global scientific teams, with external partners and with members of the public.• Key computational skills: Ligand- and structure-based drug design (including fragments), virtual screening, molecular modelling, library-design, chemoinformatics, hit-identification and lead optimisation.

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Louise Birch's current company

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Sygnature Discovery
Sygnature Discovery
Deputy Director
Nuneaton, GB
Employees
671
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9 roles · 20 years

Louise Birch work experience

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Associate Director

Current

Nottingham, England, United Kingdom

Oct 2022 - Present

Principal Scientist (Computational Chemistry)

Nottingham, United Kingdom

Nov 2019 - Oct 2022

Senior Scientist: Computational Chemistry

Nottingham

Founded in 2004, Sygnature Discovery (www.sygnaturediscovery.com ) is the United Kingdom’s largest independent provider of integrated drug discovery resource and expertise. The company adds value to clients’ research projects by providing advanced scientific knowledge and experience to accelerate hit identification, hit to lead and lead optimisation.

Aug 2014 - Nov 2019

Senior Scientist: Computational Chemistry

Cambridge, United Kingdom

Application of modelling techniques to external projects for hit identification and to guide chemistry strategy (e.g. ligand- and structure-based virtual screening and design, homology modelling, QSAR, QM, chemoinformatics). Generation of new proposals for client targets. Design of focused libraries (including kinases, GPCRs, ion channels and epigenetics).

Jan 2014 - Jul 2014

Senior Scientist: Structure Based Drug Deisgn

Established the computational chemistry group in the UK, including the identification and procurement of software and implementation of a dedicated Linux cluster. Successful track record of delivery of CADD solutions for neuroscience projects at different stages of development (target validation to lead optimization) and in library design. Project leader.

Dec 2011 - Nov 2013

Scientist: Structure Based Drug Deisgn

Jan 2009 - Dec 2011

Senior Scientist: Applied Design

Responsible for structure-based drug-design projects for both in-house and client targets, designing small molecule inhibitors and creating protein homology models, including GPCRs. Devised and conducted parallel design strategies including focused fragment libraries, induced protein flexibility, protein selectivity, QSAR and ligand-based selection.

Jan 2006 - Oct 2009
Team & coworkers

Colleagues at Sygnature Discovery

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3 education records

Louise Birch education

Education record

Tytherington County High School
FAQ

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What company does Louise Birch work for?

Louise Birch works for Sygnature Discovery.

What is Louise Birch's role at Sygnature Discovery?

Louise Birch is listed as Deputy Director at Sygnature Discovery.

Where is Louise Birch based?

Louise Birch is based in Nuneaton, England, United Kingdom while working with Sygnature Discovery.

What companies has Louise Birch worked for?

Louise Birch has worked for Sygnature Discovery, Sygnature Discovery Limited, Biofocus, Eisai, and De Novo Pharmaceuticals.

Who are Louise Birch's colleagues at Sygnature Discovery?

Louise Birch's colleagues at Sygnature Discovery include Sebastien Thueillon, Caroline Cooper, Max Shilton, Eimear Flanagan, and Prabhakarreddy Devireddy.

How can I contact Louise Birch?

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What schools did Louise Birch attend?

Louise Birch holds Doctor Of Philosophy (Phd), Chemistry from University Of Cambridge.

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