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Ellen Bennett is listed as Director of Brain Injury Biorepository at Duke University Medical Center at Duke University Medical Center (Neurology), a with 4767 employees, based in Durham, North Carolina, United States. AeroLeads shows a work email signal at duke.edu and a matched LinkedIn profile for Ellen Bennett.
Ellen Bennett previously worked as Director of Brain Injury Biorepository at Duke University Medical Center and Assistant Professor at Duke University Medical Center (Neurology). Ellen Bennett holds Doctor Of Philosophy (Phd), Micrbiology And Immunology from Mcgill University.
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Our group is primarily interested in the CNS response to acute injuries such as stroke, intracerebral hemorrhage (ICH), traumatic brain injury (TBI) and concussion (mild TBI). As a member of the Brain Injury Translational Research Center, we collaborate with other participating colleagues to translate findings made in the laboratory using transgenic animal models of brain injury to design clinically relevant studies. We are particularly interested in how specific genetic polymorphisms govern the extent of injury and recovery following these brain injuries.Stroke is a major leading cause of death in the United States and 15-30% of those who survive are permanently disabled. Spontaneous ICH accounts for 15% of all strokes but is one of the most disabling forms of stroke, with a 40-50% mortality rate within the first 30 days. TBI is also a major public health concern within both the civilian and military population, accounting for more than 1.5 million incidents in the US each year. It is estimated that as many as 3.8 million mild TBIs (concussions) occur in the US each year during competitive sports and recreational activities alone.Recovery following brain injury is variable, even within patients with similar severity of injury. A growing body of literature suggests that an individual’s genetic predisposition can contribute significantly to the extent of the injury as well as recovery. Specifically, having a ‘good’ or ‘bad’ variant of a particular gene can influence a better or worse outcome following a brain injury. To this end, we have developed a number of pilot clinical research studies as well as larger multicenter studies designed to identify genetic factors that may play a role in governing outcome following brain injury in an acute setting. It is our hope that these studies will provide additional insight into the pathophysiology of the injury and identification of novel therapeutic targets.
Listed skills include Clinical Research, Traumatic Brain Injury, Genetics And Brain Injury, Dna Banking, and 8 others.
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Brain Injury Translational Research Center, Department Of Neurology
Preparation, maintenance and analysis of human blood, tissue and DNA specimens from brain-injured subjects including stroke, SAH and TBI.
Duke University (Neurology)
My interest is in the CNS response to acute injuries such as stroke, intracerebral hemorrhage (ICH), traumatic brain injury (TBI) and concussion (mild TBI). As a member of the Brain Injury Translational Research Center , I collaborate with other participating colleagues to translate findings made in the laboratory using transgenic animal models of brain injury to design clinically relevant studies. We are particularly interested in how specific genetic polymorphisms govern the extent of injury and recovery following these brain injuries.
Durham, Nc
My lab served as a molecular biology core group in the Department of Pathology. In addition to providing molecular biology expertise to colleagues in the department, we continued studying the expression of the human and murine APOE gene in the CNS and the role of apoE in various disease states using animal models.
Durham. Nc
Alzheimer's disease research; apolipoprotein E gene (apoE) expression in CNSGene expression studies using promoter-reporter constructs to analyze human and murine apoE regulatory/promoter gene expression in cells of the CNS
Chapel Hill, Nc
Molecular NeurobiologyDevelopment of transgenic mouse models; demyelination disease (MS)Gene targeting in ES cellsCloning of novel genes from rodent brain
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Ellen Bennett works for Duke University Medical Center (Neurology).
Ellen Bennett is listed as Director of Brain Injury Biorepository at Duke University Medical Center at Duke University Medical Center (Neurology).
AeroLeads has found 2 work email signals at @duke.edu for Ellen Bennett at Duke University Medical Center (Neurology).
Ellen Bennett is based in Durham, North Carolina, United States while working with Duke University Medical Center (Neurology).
Ellen Bennett has worked for Duke University Medical Center, Duke University Medical Center (Neurology), Duke University (Department Of Pathology), Duke University, and University Of North Carolina At Chapel Hill.
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Ellen Bennett holds Doctor Of Philosophy (Phd), Micrbiology And Immunology from Mcgill University.
Ellen Bennett is listed with skills including Clinical Research, Traumatic Brain Injury, Genetics And Brain Injury, Dna Banking, Biorepository, Molecular Biology, Gene Expression, and Scientific Writing.
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