Eric Klee Email & Phone Number

A Consultant in the Division of Computational Biology, Department of Quantitative Health Sciences, with joint appointments in the Department of Clinical Genomics and in the Division of Laboratory Genetics, Department of Laboratory Medicine and Pathology. Director of Bioinformatics and the Director of the Translational Omics Program, within Mayo Clinic’s Center for Individualized Medicine. Holds the academic rank of Associate Professor of Biomedical Informatics, Mayo Clinic College of Medicine. Research focuses on the translational application of -omic technology to advance clinical diagnostics and patient care. I am actively engaged in the development and implementation of systems to support sequence analysis and interpretation of variant information for genetic testing, with a special interest in rare, undiagnosed, Mendelian Disease. The Translational Omics Program combines a multi-omic testing approach with innovative analytical methods and laboratory based functional studies to seek answers for undiagnosed disease patients. Current research includes the use of RNA-sequencing and methyl-sequencing to aid in clinical diagnoses, and anti-sense oligonucleotides as a potential therapeutic strategy for patients. Active in education, teaching clinical bioinformatics to Department of Laboratory Medicine and Pathology residents and fellows, leading a graduate course on analysis and interpretation of exome and genome data, and co-director of the Discovery Science concentration in the new Masters of AI in Healthcare. Provides mentorship to medical and predoctoral students and holds full faculty privileges in Clinical and Translational Science at Mayo Graduate School, Mayo Clinic College of Medicine.