• Performed early product development of oil-in-water nanoemulsions for delivery of small molecule drugs, diagnostic tracers, and oxygen. Optimized process parameter of product prototypes where formulations exhibiting critical quality attributes within pre-defined specifications (e.g., particle size < 200 nm) were advanced through further product development.• Executed forced degradation experiments to evaluate chemical stability of API using HPLC. Applied chemical reaction kinetics fundamentals to calculate reaction rate constant of API degradation process and impact of temperature. Observed 9-fold stability improvements of encapsulated form.• Performed particle size analysis of polymeric micelles, emulsions, and lipid nanoparticles using dynamic light scattering and microscopy. Utilized centrifugation, filtration, and extreme temperature to elicit particle coarsening and utilized colloid science fundamentals to investigate stability mechanisms.• Developed and troubleshot flow cytometry & ELISA methods and analysis of macrophages in response to hypoxic cultivation and subsequent administration of bespoke oxygen nano-carriers. Achieved an increase in intracellular pO2 from 1.0 to 7.7% in response to one dose.• Assessed reactive oxygen species upregulation in pro-inflammatory (M2) macrophages in response to LPS-mediated immune activation and quantified dose-response & potency of a small molecule scavenger using a cell-based colorimetric bioassay. Achieved 66% improvement in scavenging potency with encapsulation.

- Performed organic synthesis, purification, and characterization of small molecule anti-cancer compounds. Conducted thin-layer chromatography to monitor reaction progress, column chromatography and acid-base extraction to purify reaction products, and rotary evaporation for solvent removal. - Used NMR spectroscopy to characterize reaction product chemical structure.

- Investigated chemical fate of elemental mercury in lab scale-down of nuclear waste in Slurry Mix Evaporator at DWPF to facilitate downstream processing. Executed experiments to identify the thermodynamic and kinetic processes of the Hg extraction process. Adjusted mixture composition and mixing speed and analyzed the resulting reactants and products.- Collaborated with senior management, chemists, and engineers to extract deliverables from data analysis.