Erik Nelson

Erik Nelson Email and Phone Number

Principal Scientist @ GSK
Philadelphia, PA, US
Erik Nelson's Location
Washington DC-Baltimore Area, United States
About Erik Nelson

My research uses single-nucleus and spatial transcriptomics to map the gene expression landscape of the human brain. I develop reproducible analysis pipelines to integrate large-scale omics datasets across species and data modalities, leveraging cutting-edge machine learning methods to identify both functionally relevant gene expression signatures and potential therapeutic targets.

Erik Nelson's Current Company Details
GSK

Gsk

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Principal Scientist
Philadelphia, PA, US
Website:
gsk.com
Employees:
90451
Erik Nelson Work Experience Details
  • Gsk
    Principal Scientist
    Gsk
    Philadelphia, Pa, Us
  • Gsk
    Computational Biologist - Translational Omics
    Gsk Dec 2024 - Present
  • Lieber Institute For Brain Development
    Graduate Student Researcher
    Lieber Institute For Brain Development Aug 2019 - Jul 2024
    Washington Dc-Baltimore Area
    • Built a comprehensive molecular map of the human hippocampus using spatial transcriptomics and single-nucleus RNA-seq• Designed and implemented advanced machine learning pipelines to automate discovery of cell types and tissue cytoarchitecture• Integrated cross-species epigenomic and viral circuit tracing data using transfer learning to predict human neuron connectivity• Leveraged nonnegative matrix factorization (NMF) to uncover neuron cell states and activity-regulated gene expression signatures• Processed GWAS data and integrated with transcriptomic atlas to identify cell types and cell states vulnerable in disease• Developed scalable computational pipelines for genomics data analyses to facilitate reproducibility and accessibility
  • Massachusetts Institute Of Technology (Mit)
    Technical Research Associate
    Massachusetts Institute Of Technology (Mit) May 2016 - Jul 2019
    Greater Boston Area
    • Pioneered a high-throughput, automated confocal microscopy pipeline to rapidly scale high-quality image acquisition• Designed and optimized immunofluorescence assays to characterize pathology in mouse models of stress and Huntington’s• Collaborated with software engineers to build and implement an automated computational microscope image analysis pipeline• Contributed to 2 high-impact publications through significant experimental and computational efforts
  • William & Mary
    Honors Research Fellow
    William & Mary Apr 2015 - May 2016
    Dublin, Ireland
    With an interdisciplinary approach, I explored the formation, development, and alteration of collective memory within social groups by combining principles from neuroscience, psychology, and sociology.
  • William & Mary
    Undergraduate Research Assistant
    William & Mary Sep 2013 - May 2016
    I conducted rodent behavioral assays to examine the role of the basal forebrain cholinergic system in attention and impulsivity. I collected and analyzed data and assisted with rat surgeries.
  • Cincinnati Children'S Hospital Medical Center
    Summer Research Fellow
    Cincinnati Children'S Hospital Medical Center May 2014 - Aug 2014
    I studied hippocampal dentate granule cell neurogenesis and development in the context of epilepsy. I characterized a novel transgenic mouse model and created 3D reconstructions of hippocampal neurons to analyze morphological changes. I performed mouse breeding and other colony maintenance tasks.

Erik Nelson Education Details

Frequently Asked Questions about Erik Nelson

What company does Erik Nelson work for?

Erik Nelson works for Gsk

What is Erik Nelson's role at the current company?

Erik Nelson's current role is Principal Scientist.

What schools did Erik Nelson attend?

Erik Nelson attended The Johns Hopkins University School Of Medicine, William & Mary.

Who are Erik Nelson's colleagues?

Erik Nelson's colleagues are Arpit Dixit.

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