Erik Nelson Email & Phone Number

Philadelphia, Pa, Us

Washington Dc-Baltimore Area

• Built a comprehensive molecular map of the human hippocampus using spatial transcriptomics and single-nucleus RNA-seq• Designed and implemented advanced machine learning pipelines to automate discovery of cell types and tissue cytoarchitecture• Integrated cross-species epigenomic and viral circuit tracing data using transfer learning to predict human neuron connectivity• Leveraged nonnegative matrix factorization (NMF) to uncover neuron cell states and activity-regulated gene expression signatures• Processed GWAS data and integrated with transcriptomic atlas to identify cell types and cell states vulnerable in disease• Developed scalable computational pipelines for genomics data analyses to facilitate reproducibility and accessibility

Greater Boston Area

• Pioneered a high-throughput, automated confocal microscopy pipeline to rapidly scale high-quality image acquisition• Designed and optimized immunofluorescence assays to characterize pathology in mouse models of stress and Huntington’s• Collaborated with software engineers to build and implement an automated computational microscope image analysis pipeline• Contributed to 2 high-impact publications through significant experimental and computational efforts

Dublin, Ireland

With an interdisciplinary approach, I explored the formation, development, and alteration of collective memory within social groups by combining principles from neuroscience, psychology, and sociology.

I conducted rodent behavioral assays to examine the role of the basal forebrain cholinergic system in attention and impulsivity. I collected and analyzed data and assisted with rat surgeries.

I studied hippocampal dentate granule cell neurogenesis and development in the context of epilepsy. I characterized a novel transgenic mouse model and created 3D reconstructions of hippocampal neurons to analyze morphological changes. I performed mouse breeding and other colony maintenance tasks.

Doctor Of Philosophy - Phd, Cellular And Molecular Medicine

Co-mentored by Dr. Keri Martinowich, Dr. Stephanie Hicks, and Dr. Kristen Maynard. Thesis: Integrative transcriptomic profiling.

Bachelor’S Degree, Neuroscience And English