Vishwanath Gaitonde Email & Phone Number

High Point, NC, US

High Point, NC, US

East Rutherford, New Jersey, US

East Rutherford, New Jersey, US

East Rutherford, New Jersey, US

East Rutherford, New Jersey, US

• Design, develop, and optimize chemical processes for multi-kilo scale demo run, GMP, and nGMP production campaigns
• Develop accurate final processes BPD to build BOP for production campaigns to achieve deviation less executed MBR’s
• Meticulously execute MBR during GMP and nGMP production campaign to support clinical trial from Phase I – Phase III
• Supervise raw material procurement, tracking, use test, release, and readiness to achieve on time production schedule
• Accountable for overall scheduling, planning, achieving on time pilot plant production, QC testing, and material release
• Generate and deliver detailed weekly report for TC with the client team, and comprehensive project completion report

Brentford, Middlesex, GB

• Build molecular model with a crystal structure to assist SAR development to improve potency and DMPK properties
• Generate hypotheses from existing SAR to design, synthesize molecules with improved solubility and permeability
• Function as part of a medicinal chemist’s team optimizing lead compound to target viral respiratory diseases
• Engage in brainstorming sessions and perform large-scale synthesis of key intermediates for team use
• Carry out large scale purification and characterization of compounds for STS testing
• Trained in eLNB, Spotfire, Helium, and MOE software operation

Toledo, OH, US

• Synthesized a series of β-glycosyl amide, key motifs in glycosyl amino acid, employing dinitrobenzenesulfonamide chemistry. Moreover, studied a novel chemoselective amide ligation between glycosyl sulfonamides and.
• Mtb GlgE is a genetically validated drug target for the development of TB treatment. Streptomyces coelicolor GlgEI, a glycoside hydrolase involved in α-glucan biosynthesis was utilized as model enzyme for.
• Generated maltosyl donor and acceptor building blocks via a concise synthetic route to construct oligosaccharide units using pre-activated glycosylation technique. Further, strategically assembled oligosaccharide units.
• Designed and developed synthetic method to access glycosylfluoride compounds as i) potential mechanism-based inhibitors, and ii) to identify the active site residues of Mtb GlgE. Installed fluorine atom at the C-5.
• Developed a rapid synthetic route producing bis-furan diol (BFD) as a platform molecule to generate novel amorphous polyester, bis-furan polyester. Furthermore, examined BFD for packing, H-bonding and potential.

Toledo, OH, US

Taught undergraduate Organic chemistry laboratory courses: OChem - 2460 and OChem - 2470Tutored Chemistry help center: General chemistry and Organic chemistry academic and laboratory courses

Taught undergraduate General chemistry, Organic chemistry, Science I & II academic courses

• Custom synthesis in Contract Research Organization -
• Designed and executed synthetic route to generate a library of small molecule pyrazoline derivatives
• Synthesized numerous heterocyclic, bicyclic, and other key organic intermediates for use in drug discovery
• Managed individual projects and concurrently worked as part of a team to achieve target delivery deadlines

IN

• Synthesized intermediates of (S,R)-BIPHEMPHOS ligand for use in asymmetric hydroformylation catalysis

Doctor Of Philosophy (Phd), Chemistry

Master Of Science (Ms), Organic Chemistry

Bachelor Of Science (Bs), Chemistry And Biochemistry