Gregory Downs Email & Phone Number

Toronto, Ontario, Canada

Toronto, Canada Area

The Advanced Molecular Diagnostics Laboratory at the Princess Margaret Cancer Centre develops and implements clinical genomic tests and performs molecular profiling of tumor specimens.

Guelph, Ontario

BioDatAlign Bioinformatics is a full-service bioinformatics shop specializing in the analysis of next-gen sequencing data. We are well versed in transcriptome profiling via RNA-Seq, de novo assembly of transcriptomes or genomes, differential gene expression, identification of novel splice variants, and coexpression network analysis.

Guelph, Ontario

I am responsible for portions of two graduate level courses designed to train a new generation of Bioinformatics experts. We will be working through an RNA-Seq experiment, and introducing basic programming concepts using Perl and the Bash shell in a HPC environment. Students will gain experience with the command-line Unix/Linux environment, using the latest software for NGS data analysis, and learn to manipulate large-scale biological data programmatically. BINF 6110 Genomic Methods for BioinformaticsBINF 6410 Bioinformatics Programming

Guelph, Ontario, Canada

My PhD research involved using coexpression networks to study the genome-wide regulation of gene expression using maize as a model system. I am also interested in using RNA-Seq data to answer questions about alternative splicing events and allele-specific expression.

• Data Manager for specimen data for the DNA Barcoding project.• Programmer for internal data management systems.• Trained and coordinated data management team.

Vancouver, Canada Area

• System administration, troubleshooting, and general consultation.• Maintained a heterogeneous network (Windows, Macintosh, Unix).• Managed web (HTML, PHP), mail, and backup servers, DNS and spam filtering.• Clients included UBC Department of Microbiology and Immunology, The Center for Microbial Diseases and Immunity Research, and Inimex Pharmaceuticals.

Sweden

• System Administration for ~40 Linux machines, PCs, and various laptops, including web and mail services.• Oversaw the integration of a Beowulf cluster, migrated the network from NFS to AFS, and redesigned the system architecture.• Automated installations and upgrades through RedHat Kickstart.• Developed scripts (BASH, Perl) to automate common tasks.• Resolved networking issues and offered user support.

Richmond Hill, Canada

formerly PDi-Research Laboratories, Inc.• Chemical synthesis of pharmaceutical impurities and metabolites.• Member of the Joint Health and Safety Committee• Designed and conducted safety and WHMIS training sessions.

Ph.D., Bioinformatics

Ontario College Graduate Certificate, Bioinformatics

B.Sc., Chemistry