Giulia Grimaldi Email & Phone Number

United Kingdom

Bradford, England, United Kingdom

G Cubed develops boardgames that align with the National Curriculum of England, allowing students to learn through playing.

DLOC Biosystems is a CRO developing new technology to enable pre-clinical trials on-chip.

Providing biomedical research expertise on a freelance basis, including: - Medical/scientific writing; literature reviews, drafting and proofreading academic manuscripts - Data analytics; biostatistics, publication-quality data visualisations- Creation of course contents

Oslo Area, Norway

Responsible of all aspects of a service business:-customer service-finances -business growth-public relations and social media

Oslo Area, Norway

Understanding the role of TIPARP (TCDD inducible poly-ADP-ribose polymerase) in conferring protection against different types of stresses and contaminants. - Development and execution of research programs- Management and mentoring of junior staff and students- Data analysis, problem solving and trouble shooting- Presentation and communication of empirical data in both written and oral form - Establishment and maintaining cross-functional and cross-cultural collaborations Techniques:-Molecular Biology (RNA and DNA isolation from tissues and cells, qPCR, Co-IP, Western blot, ChIP)-Biochemistry (Protein Purification, ADP ribosylation assays)-Imaging Techniques (Confocal and Super resolution microscopy)-Cell culture (including establishment of primary cell lines)-Animal handling (incl. microdissections)

I led an expedition with the aim to collect data to study the amount of uplift of the Aleutian Islands since the last ice-age and to assess the extent of microplastic pollution even in remote areas. As recipient of the Scientific Exploration Society Neville Shulman Film Award I also made a short film highlighting the need and importance of preserving the natural heritage above and below water.My responsibilities as the project manager included:- planning, organising and leading the expedition and the team- seeking funding and sponsorship- establishing collaborations with scientists - collecting data- videoing and film editing- managing social media- organising on-site logistics

Use of photoreceptor precursor cells for cone replacement therapy to relieve neural degeneration. I demonstrated increased efficiencies in cone-cell transplantation in adult retina as well as investigated the potentially detrimental effects of a rod-rich host to cone-integration. I also designed, developed and performed preliminary experiments to study changes in DNA methylation in developing photoreceptors – both in rods and in cones. My responsibilities as a research associate included, but were not limited to:- designing the research- carrying out the experimental work- developing the relevant research protocols- analysing data- presenting data both in the written and oral form- establishing and maintaining collaborations with other laboratories- mentoring junior members of the lab- animal handling and colony management Techniques used:- tissue handling and microdissection- retinal microdissection- cryosectioning- immunohistochemistry- confocal microscopy- immunoassays

London, United Kingdom

Epigenetic programming in human endometrial stromal cellsI focused on the role of epigenetics in decidualization of primary cultures of human endometrial stromal cells (hESCs). I discovered how methyltransferase EZH2 is regulated in response to hormonal stimuli and the effects it has on the chromatin pattern in promoter regions of, but not limited to, decidual marker genes. Furthermore, I worked on genome-wide changes in DNA methlyation upon decidualization. See attached publications for further details. My responsibilities as a PhD student included:- designing experiments- carrying out all the experiments- data analysis- presentation of the results in written (papers, posters and thesis) and oral form (seminars)- liaising with clinics to obtain specimens- establishing and maintaining collaborations with bioinformaticians Techniques used:- Chromatin and Methylated DNA Immunoprecipitation assays- Genome-wide data set analysis (microarray, ChIP-on-chip and MeDIP-seq)- Primary cell culture- PCR (qPCR and RT-qPCR)- Immunoassays- Western blot

London, United Kingdom

Understand the mechanisms for generating health eggs by the maintenance of chromosome cohesion and cell cycle arrest during prolonged oogenesis.My responsibilities as a postgraduate student included:- establishing ChIP protocols- liaising with other labs and maintaing collaborationsTechniques used:- Chromatin Immunoprecipitation- Cell culture

Newcastle Upon Tyne, United Kingdom

Characterisation of the flagellar filament assembly in Caulobacter crescentus.I characterised flmD mutants in Caulobacter crescentus to clarify the role of posttranslational modifications in the regulation of flagellar filament assembly.My responsibilities as a postgraduate researcher were:- carry out all the experimental work- analyse the dataTechniques used:- bacterial cloning- PCR (PCR, sowing PCR)- bacterial motility and secretion assays - western blot- transmission electron microscopy

Pavia Area, Italy

Purification of the RNA polymerase complex of Bacillus subtilis and its regulatory factors.I purified the RNA polymerase complex of Bacillus subtilis and its regulatory factors to then allow the study of how transcription of swrA, essential for bacterial swarming, is regulated.As an undergraduate intern, I was responsible for:- carrying out the experimental work- analysing the dataTechniques used: - bacterial cloning- Protein purification (FPLC)- SDS-PAGE

Doctor Of Philosophy (Phd), Epigenetics

PhD student with Prof. Jan Brosens in the Laboratory of Uterine Biology, Imperial College of Science, Technology & Medicine. Thesis.

Master Of Science (Msc), Industrial Biotechnology, 110/100 Cum Laude

This is a two year interdisciplinary degree focusing on molecular biology and chemistry with the aim to give a strong background.

Bachelor Of Science (Bsc), Biotechnology, 110/110

This degree provides a strong background in molecular mechanisms and delivers the ability to carry out protocols in which living organisms.