With a BSc in Biochemistry from the University of Leeds and two years of experience in pharmaceutical settings, I have gained extensive experience in protein purification, molecular biology, and analytical techniques. I am interested in expanding my skill set in biochemistry techniques, and molecular and cellular biology and working within a challenging interdisciplinary environment.From my laboratory experiences in industry, I gained experience in:- Gel Electrophoresis- AKTA operation and chromatography- UF/DF- Tecan 200 & Freedom EVO- Labchip- UPLC/HPLC ( SEC, ProA, reverse phase, ion exchange) - ELISADuring my dissertation project at the University of Leeds, I applied myself to molecular biology and protein engineering to create structural mutants of an S.aureus Elongation factor G construct. From my experience in a research lab I developed skills in :- PCR- DNA extraction- E.Coli cell culture- Aseptic technique- Multistage protein purification - NMR.Overall, I am a creative and analytically-minded individual with a continuous desire to learn and develop new skills. With my diligent approach and strong problem-solving abilities, I thrive in collaborative environments and am eager to tackle new challenges.
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Scientist Ll4BasebioCambridge, Gb -
Associate ScientistUcb Aug 2023 - Jul 2024Slough, England, United KingdomIndependently planned and executed chromatography and UF/DF experiments and follow-up analysis to characterise the downstream process for a therapeutic fragment antibody.Purified over 40 samples using automated liquid handling robotics, guaranteeing clear and high-quality results of HPLC analysis of eluate samples, free of host cell proteins and contaminants, improving the reliability of experimental results.Maintained a safe and organised lab environment adhering to health and safety standards, COSHH regulations and standard operating proceduresSoftware: AKTA, Empower, Tecan Freedom EVOware, Microsoft Office suite, Go-silico -
Undergraduate Student ResearcherUniversity Of Leeds Oct 2022 - Dec 2022Leeds UkUndertaking a final year research project creating structural mutants of an S. Aureus Elongation Factor G construct for NMR analysis.Laboratory techniques:QuickChange PCR, E.Coli cell culture, transformation, plasmid miniprep extraction, protein purification using Ni-NTA affinity and size exclusion chromatography, SDS-PAGE, Induction, sequence analysis, NMR. -
Down-Stream Processing Placement StudentFujifilm Diosynth Biotechnologies Sep 2021 - Aug 2022Billingham, England, United KingdomCollaborated working on various customer projects, operating downstream processing equipment to achieve GMP standard protein purification and processing. Laboratory skills:Protein purification synphonx and AKTA models at a variety of scales, Solo VPE, Nanodrop, Buffer Preparation, SDS-PAGE.worked within a team to develop a high through put assay to identify ideal refolding conditions of inclusion bodies found within E.coli cells lines.Skills:Tecan liquid handling automation, LabCHIP, data analysis, -
BaristaEmma'S Tea Parlour Jul 2016 - Jul 2017Holmfirth, England, United Kingdom
Heather Malcolm Education Details
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Biochemistry With Industrial Placement -
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Holmfirth High SchoolGcse
Frequently Asked Questions about Heather Malcolm
What company does Heather Malcolm work for?
Heather Malcolm works for 4basebio
What is Heather Malcolm's role at the current company?
Heather Malcolm's current role is Scientist ll.
What schools did Heather Malcolm attend?
Heather Malcolm attended University Of Leeds, Greenhead College, Holmfirth High School.
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