Hui Tong Email & Phone Number

Professional Experience:• Conducted MS (ESI/APCI), LC-UV/MS, GC/MS (EI) experiments to confirm the MW of small molecules (routine, throughput 25/day) for chemists. Performed structure elucidation if needed using LC-MS/MS, exact MS measurement, H/D exchange.• Conducted LC-UV/MS, LC-MS/MS and MALDI experiments to study peptides, proteins and RNAs (non-routine) for biologists, including antibody drug conjugation, protein labeling, protein/peptide sequencing after trypsin digestion, binding site identification.• Ran high throughput screening assays to identify small molecules binding to proteins using MS.• Independently developed automation software packages to improve efficiency and productivity.1. An electronic MS data processing & reporting system including: software to process MS data acquired by Waters mass spectrometers; software to interpret mass spectra of small molecules and generate interpretation reports; software to e-mail MS data & reports to chemists.2. Excel macros to calculate values and parameters for various pharmaceutical profiling (Drug Metabolism & Pharmacokinetics/DMPK) assays.3. Software to e-mail HRMS, LC/MS, NMR, IR data & reports to the chemists.4. Software to remotely monitor the performance of “open-access” Waters and Agilent LC/MS.5. Software to process purity/integrity assay data acquired by Agilent 1100 MSD LC/MS.• Performed routine maintenance of multiple LC/MS instruments including minor repairs and data archiving.• Experienced in Waters LCT, Quattro micro, ZQ, Q-TOF Premier/Acquity UPLC and Agilent 1100/1200 MSD LC/MS, HP 5890/5972 GC/MS, Applied Biosystems Voyager MALDI-TOF, Bruker 300MHz NMR.• Supervised the Discovery “Open Access” LC/MS facility to support chemists (including training).• Presented posters at the annual Wyeth Discovery Symposiums as the primary author.Specialties: Visual Basic 2008/2005, VB.NET, Visual Basic 6, VBA for Excel & Word, Access, Adobe Acrobat, HTML, web page design, UNIX

Listed skills include Lc Ms, Hplc, Mass Spectrometry, Analytical Chemistry, and 11 others.