Irene Chen

Irene Chen Email and Phone Number

Scientific Program Lead @ Gladstone Institutes
San Francisco, CA, US
Irene Chen's Location
San Francisco, California, United States, United States
About Irene Chen

Accomplished cell biologist and molecular virologist with a robust background in academic and industry research, complemented by experience gained from a leading venture capital firm. Expertise in molecular virology, epigenetics, and cell biology. Eager to leverage my multidisciplinary background to contribute to the growth and success of future human therapeutic companies and startups.

Irene Chen's Current Company Details
Gladstone Institutes

Gladstone Institutes

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Scientific Program Lead
San Francisco, CA, US
Irene Chen Work Experience Details
  • Gladstone Institutes
    Scientific Program Lead
    Gladstone Institutes
    San Francisco, Ca, Us
  • The Column Group
    Swanson Fellow
    The Column Group Oct 2023 - Oct 2024
    •Sourced early-stage investments and identified potential opportunities, resulting in successful creation of NewCo.•Led and supported due diligence process for potential investments.•Established and nurtured relationships with leading academics and innovators to access cutting-edge research.•Collaborated with senior leadership on target selection, nominating targets with highest probability of success based on existing chemical matter, safety, and available disease model validation data.•Played a key role in company building activities: crafting investment memos, competitive intelligence, securing initial funding, and operational support.
  • Gladstone Institutes
    Postdoctoral Scholar
    Gladstone Institutes Apr 2023 - Sep 2023
    San Francisco, California, United States
    •Directed four collaborative research projects involving multiple functional teams to publication.•Managed BSL-3 level components for 8+ collaborative antiviral discovery projects for NIH-funded AViDD program.•Worked cross-functionally with structural and mass spectrometry teams to characterize SARS-CoV-2 variants.•Communicated progress and roadblocks to collaborators and recommended solutions to ensure timely progress.
  • University Of California, San Francisco
    Graduate Student
    University Of California, San Francisco Sep 2017 - Mar 2023
    •Characterized humoral responses and novel host-pathogen interactions during SARS-CoV-2 infection.•Investigated the basic molecular mechanism behind HIV latency reversal mediated by FOXO1 inhibition.
  • Salk Institute For Biological Studies
    Undergraduate Research Assistant
    Salk Institute For Biological Studies Nov 2013 - Jul 2017
    La Jolla, California
    •Started a new line of investigation into the function of a novel adenovirus protein in viral replication.•Engineered recombinant adenovirus for analysis on fluorescent assay, immunoprecipitation, and immunofluorescence.•Evaluated diffraction patterns with molecular replacement software to determine protein structure of small viral proteins •Cultured various cancer cell lines for adenovirus infection experiments to visualize protein localization.
  • Genentech
    Research Intern
    Genentech Sep 2016 - Dec 2016
    San Francisco Bay Area
    •Contributed to a Cell publication on the therapeutic potential of small molecules targeting TFs in breast cancer.•Started a new line of questioning into the structural interactions of small molecules and the estrogen receptor.•Validated mechanisms of SERM and SERD in inhibiting downstream effects of estrogen receptor activation.•Evaluated breast cancer drug compounds’ effect on estrogen receptor mutants in estrogen reporter assay.
  • Lmu - Ludwig-Maximilians-Universität München
    Daad Scholar
    Lmu - Ludwig-Maximilians-Universität München Jun 2016 - Sep 2016
    Munich Area, Germany
    •Selected as one of the top 5% of applicants to the international research program run by the German government. •Concluded the lack of poly-ADP-ribosylation’s role in the mobilization of heat shock proteins after stress.•Assessed intracellular response, specifically poly-ADP-ribosylation, to cell stress and DNA damage.•Visualized cellular location of DNA Damage repair proteins after oxidative stress with live cell imaging.•Generated Macrodomain and TARG knockout cell lines using CRISPR technology in U2OS cell lines.
  • Mackay Memorial Hospital
    Research Trainee
    Mackay Memorial Hospital Jul 2015 - Aug 2015
    New Taipei City, Taiwan
    •Explored molecular pathways of inflammasome-induced pyroptosis and its involvement in pre-term births.•Evaluated effects of the addition of drugs and inhibitors on cell vitality with fluorescent flow cytometry.•Investigated the effects of pyroptosis-inducing cellular insults on oocyte maturation and morphology in mice.•Optimized drug concentrations and time-points for cell proliferation assays to detect pyroptosis phenotypes.
  • Caltech
    Student Intern
    Caltech Jun 2011 - Sep 2013
    Pasadena, California
    •Investigated the reaction kinetics of the formation and behavior of plant SRP protein complexes.•Developed new protocols for the expression and purification of co-translational pathway proteins. •Designed SRP clones for optimal hetero-dimerization for crystallization.

Irene Chen Education Details

Frequently Asked Questions about Irene Chen

What company does Irene Chen work for?

Irene Chen works for Gladstone Institutes

What is Irene Chen's role at the current company?

Irene Chen's current role is Scientific Program Lead.

What schools did Irene Chen attend?

Irene Chen attended University Of California, San Francisco, University Of California San Diego, Arcadia High School.

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