James Tronolone, Ph.D. Email & Phone Number

Austin, Tx, Us

Austin, Texas, United States

College Station, Texas, United States

• Pioneered a novel research domain merging AI with biomedical data and disease models for the purpose of developing physiologically relevant standards of vascular disease modeling and therapeutic intervention.• Invented the Vascular Network Quality Index, an artificial intelligence-based metric predicting the oxygen delivering potential of tissue engineered vascular networks from fluorescent micrographs with 94% accuracy.• Engineered a microfluidic model of the insulin-secreting vascularized pancreas and induced disease phenotypes, measured as a 75% decrease in insulin production, via hypoxia challenge.• Showcased professional communication skills by delivering invited oral and poster talks, publishing 17 manuscripts (8 first-author) achieving an h-index of 5, and devised NIH, AHA, and NSF grant applications based on original, preliminary research.

College Station, Texas, United States

• Organized and communicated BSL-2 biosafety and biohazard awareness trainings for over 10 researchers and routinely tested and maintained BSL-2 safety equipment (emergency eye washes, showers, fume hoods, and biosafety cabinets) leading to a 100% inspection passing rate.

College Station, Texas, United States

• Developed a general good practices manual to prevent contamination and ensure the proper culturing of multiple mammalian and rodent primary cells, immortalized cancer cell lines, and stem cells, according to GMP guidelines.

College Station, Texas, United States

• Acted as a secondary instructor for the BMEN 341 Biofluid Mechanics course• Led the transition of an 80-student in-person lecture to a remote format due to the COVID-19 Pandemic.• Held regular small group sessions reviewing homework and exam problems, simplifying and explaining complex fluid dynamics principles to enhance comprehension of biofluid mechanics principles through personalized guidance and support.

College Station, Texas, United States

• Managed a $43k/semester lab supply budget allocated for tissue culture, microfabrication, microscopy, and general office supplies, consumables, and equipment servicing.• Ensured plastic-ware, sterilizing alcohols, personal protective equipment, and other biomedical research products were available in the lab despite the COVID-19 pandemic causing high lead times and shortages.

Silver Spring, Md

• Managed two research projects aimed at translating organ-on-a-chip technology to basic biomedical research.• Engineered a pump-less, modular microfluidic device based on Darcy-Weisbach and Bernoulli principles that enabled long-term culturing of tissue-engineered blood vessels for downstream assays.• Derived lymph node stroma-like cells from multipotent stromal cells (MSCs) using a differentiation cocktail based on previous work and a review of relevant literature, and analyzed immune cell proliferation in response to co-culturing with lymph stroma-like MSCs using flow cytometry.• Gained insights into regulatory processes and drug/biologics evaluation via mentorship by experienced reviewers.

Washington D.C. Metro Area

Advisor: Saniya LeBlanc, Ph.D.

Washington D.C. Metro Area

Doctor Of Philosophy - Phd, Biomedical Engineering, 3.81

Dissertation Title: "AI-Enabled Vascularized Microphysiological Systems for Disease Modeling and Translational Medicine"

Master Of Science (M.S.) - Summa Cum Laude, Biomedical Engineering, 4.00

Bachelor Of Science (B.S.) - Magna Cum Laude, Biomedical Engineering, 3.73

Activities and Societies: Biomedical Engerieering Society, Phi Sigma Kappa Fraternity, Tau Beta Pi, Order of Omega

Education record