Jason Poole Email and Phone Number
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Experienced Director in oncology and liquid biopsy with technical expertise in molecular diagnostics and assay development. qPCR and NGS specialist. In depth knowledge of CANCER, CELL-CYCLE and STEM CELL differentiation pathways. Expertise in functional ASSAY DEVELOPMENT using cell free DNA, circulating tumor cells, viral RNA and human cell lines. Good written and oral communication.• MOLECULAR: Expert in fluorophore use for molecular, genetic and cellular assays• CELL: Extensive cell line development skills. Use and functional characterization of human tumor, adherent, suspension and stem cell lines.• HTS: Experience with robotics and liquid handlers for high throughput assay developmentSpecialties: CANCER Biology (Tumor Suppressors)STEM CELL BiologyMITOCHONDRIAL Physiology and GeneticsGENE EXPRESSION and Regulation, Signal TransductionCellular response to small moleculesNext Generation Sequencing Analysis (NGS)qPCR DIAGNOSTICS assay developmentIn vitro Cell ASSAY DEVELOPMENTLife Science PRODUCT DEVELOPMENTCLINICAL DIAGNOSTIC assay development
Aegea Biotechnologies
View- Website:
- aegeabiotech.com
- Employees:
- 8
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Chief Scientific OfficerAegea BiotechnologiesSan Diego, Ca, Us
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Chief Scientific OfficerMdxhealth Dec 2022 - PresentIrvine, Ca, Us -
Vice President, Research And DevelopmentActive Motif Nov 2020 - Dec 2022Carlsbad, California, Us -
Vice President Research And DevelopmentBiocept, Inc. Aug 2018 - Nov 2020San Diego, California, Us -
Sr. Director, Molecular Assay DevelopmentBiocept, Inc. Feb 2015 - Aug 2018San Diego, California, UsDeveloping leading technology non-invasive circulating tumor cell (CTC) and cell free DNA (cfDNA) cancer diagnostics.
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Director, Research And DevelopmentTrovagene, Inc. Sep 2013 - Jan 2015San Diego, California, UsBuilt and directed the team responsible for commercializing and developing Trovagene's Precision Cancer Monitoring platform. Creator of their quantitative NGS based molecular assay used for the detection of cell free tumor mutations found in urine. -
Senior Scientist, Diagnostic Assay DevelopmentTrovagene, Inc. Jan 2013 - Sep 2013San Diego, California, UsAssay Development for Transrenal Molecular Diagnostics. We focus on the detection and monitoring of cancer and infectious disease using transrenal nucleic acids. Core responsibilities include technology evaluation, testing and development for use in transrenal diagnostics. Biomarker identification and target selection for new diagnostic assays. Design, development and analytical and clinical validation of novel transrenal assays.
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Senior Scientist, Molecular Assay DevelopmentMerck Kgaa, Darmstadt, Germany Jul 2009 - Dec 2012Darmstadt, DeResponsible for most aspects of product development from concept and market assessment to R&D and product launch. Technical Lead with direct and indirect reports. New technology evaluation in the molecular and genetic space, licensing and acquisition as well as troubleshooting current product manufacturing issues and QC assay development and optimization.• Lead scientist for the molecular biology group with direct personnel management responsibilities. • Developed custom qPCR, expression and Next Generation Sequencing assays. • Product development from concept and market assessment to R&D and product launch and documentation activities.• QC assay development and optimization, troubleshooting current product manufacturing issues,• Technology evaluation for licensing novel qPCR and molecular genetic technologies. -
Sr. Development Scientist, Qpcr Molecular DiagnosticsNanogen Aug 2008 - Jul 2009Platform development of novel influenza qRT-PCR diagnostic tests founded on proprietary minor groove binding fluorophores. Managing research associates in our BSL-2e facility and molecular testing environment working with live Influenza virus including avian and swine flu. Development of a robust and sensitive molecular assay for clinical diagnostic use.• Lead scientist for an influenza qPCR diagnostic test founded on fluorophore labeled minor groove binding probes. • Development and troubleshooting of a diagnostic testing platform using microfluidic reaction cartridges and a microthermal circuitboard• Process optimization for a high-throughput clinical diagnostic assay. • Managing research associates in a BSL-2e facility and molecular testing environment working with live Influenza virus.
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Postdoctoral Researcher, Mitochondrial GeneticsUniversity Of California, Irvine May 2004 - Aug 2008Irvine, Ca, UsDeveloped molecular and biochemical multi-well plate assays for the investigation of physiological facets of mitochondrial function in human metabolic disease and embryonic stem cells. Clinical diagnostic assay development for use in the genetic diagnosis of mitochondrial disease. Studies of the physiological and genetic changes of mitochondria during adaptive selection and human migration. Director of the Center for Mitochondrial Medicine’s human cell culture facility including the cultivation of human embryonic stem cells. -
Phd Candidate, Cancer GeneticsUniversity Of Illinois At Chicago Aug 1998 - Apr 2004Biomarker discovery of cell cycle checkpoint genes through microarray screens of human tumor cells. Investigation of the effects of p21WAF1 mediated changes in senescence related gene expression. Identified cis-acting promoter elements in novel genes regulated by p21 and identified transcription factors important in their regulation. Confirmed the validity of these biomarkers with retroviral expression vectors and development of an in vitro small molecule screening platform.
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Research AssociateIntegrated Genomics Sep 2000 - Sep 2001UsRunning high-throughput assays including sequencers and operating a CRS robotics arm equipped table for high-throughput DNA isolation, creating bacterial archives and high-throughput sequencing reactions.
Jason Poole Skills
Jason Poole Education Details
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Northwestern UniversityMolecular Endocrinology -
University Of Illinois ChicagoMolecular Genetics
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University Of Colorado BoulderPsychology/Behavioral Neuroscience
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University Of Regensburg
Frequently Asked Questions about Jason Poole
What company does Jason Poole work for?
Jason Poole works for Aegea Biotechnologies
What is Jason Poole's role at the current company?
Jason Poole's current role is Chief Scientific Officer.
What is Jason Poole's email address?
Jason Poole's email address is jp****@****tif.com
What is Jason Poole's direct phone number?
Jason Poole's direct phone number is +194930*****
What schools did Jason Poole attend?
Jason Poole attended Northwestern University, University Of Illinois Chicago, University Of Colorado Boulder, University Of Regensburg.
What skills is Jason Poole known for?
Jason Poole has skills like Assay Development, Molecular Biology, Qpcr, Life Sciences, Genetics, Cell, Cell Culture, Dna, Dna Sequencing, Stem Cells, Cancer, Sequencing.
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