Jason Belsky Email and Phone Number
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I am currently interested in using bioinformatics and computational biology techniques to ask specific mechanistic biological questions, with an emphasis on next-generation sequencing (principally Illumina) technology to interrogate the genome. My current focus is on deciphering the rules of DNA sequence and chromatin architecture (e.g. nucleosomes, transcription factors, and replication proteins) that regulate replication and transcription across the genome. I've used a combination of chromatin immunoprecipitation (ChIP), micrococcal nuclease (MNase), DNase, and genomic replication timing assays to answer these questions, using a plethora of open-source bioinformatics tools (Bowtie and samtools especially) along with custom R, Java, and bash scripts adapted from many great bioinformatics papers (Fseq and MACS in particular).Although I began my Bioinformatics PhD in 2010, my research experience commenced with four years of experimental work in two genetics labs (two years at Cornell as an undergrad, and then two years at the NIH as a postbacc). While at the NIH, I was fortunate enough to be in a lab at the forefront of the next-generation sequencing revolution, revealing to me a new field that fit particularly well with my bioengineering background. In the future, I'd like to focus on translational bioinformatics and personalized genomic medicine.I greatly value teaching and mentoring, having been inspired by great professors and graduate student/postdoc mentors in my undergraduate, NIH, and graduate research experiences. To further these principles, I've assisted in the design of a 6-class, 2-week "Bioinformatics Introduction for the Non-Computational Biologist", which I helped teach in 2013, 2014, and 2015 (course table of contents: https://goo.gl/6KUWCb). Currently, my passion is in improving the career development resources for the Duke CBB program, collating the many great resources available at Duke and across the web.
Ambry Genetics
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Manager, BioinformaticsAmbry Genetics Apr 2022 - PresentAliso Viejo, Ca, UsI currently manage the bioinformatics dev-ops team responsible for ensuring that all of Ambry's bioinformatics pipelines are successfully deployed. My team also includes software engineers who develop APIs and Ambry's internal dashboard reporting interface. We recently completed a migration of one of our internal bioinformatics pipeline to aws, establishing a CI/CD workflow through AWS Code Pipeline and Cloudformation Template deployment via AWS Service Catalog.
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Bioinformatics Scientist IiiAmbry Genetics Jan 2021 - Mar 2022Aliso Viejo, Ca, Us
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Associate Staff BioinformaticianQiagen Apr 2019 - Jan 2021Venlo, Limburg, NlLead OmicSoft Bioinformatician- Managed and trained five bioinformaticians in producing content updates and handling all data processing tasks- Initiated a large-scale code cleanup and reimplemented essential methods that were lacking documentation- Expanded data processing capabilities on Amazon Web Services by developing a python package using the boto3 module -
Bioinformatics Principal ScientistQiagen Sep 2016 - Apr 2019Venlo, Limburg, NlI work at OmicSoft Corporation, now a QIAGEN company as of January 2017.Updating OmicSoft's OncoLand with recently released oncology datasets from various cancer consortia. Establishing curation and analysis pipelines to ensure all data is uniformly processed.
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Bioinformatics Principal ScientistOmicsoft Corporation Sep 2016 - Jan 2017OmicSoft Corporation is now a QIAGEN company (as of January 2017)
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Bioinformatics Scientist (Contractor)Basf Plant Science Feb 2016 - Jun 2016Ludwigshafen, De -
Postdoctoral Research ScholarDuke University, Center For Genomic And Computational Biology (Gcb) Jan 2016 - Feb 2016Durham, Nc, UsMacAlpine LabPharmacology and Cancer BiologyCurrently completing analysis of several remaining chromatin/MNase projects in S. cerevisiae and Drosophila, which will hopefully be ready for publication soon. -
Graduate Student In Computational Biology And BioinformaticsDuke University, Center For Genomic And Computational Biology (Gcb) Aug 2010 - Dec 2015Durham, North Carolina, UsMacAlpine LabPharmacology and Cancer BiologyI'm interested in profiling the chromatin environment around replication origins in Saccharomyces cerevisiae. Even though a specific sequence motif exists at yeast replication origins (this does not appear to hold true for other species), there are only ~350 functional origins despite thousands of possible sequence matches. This implies that the chromatin environment, in particular nucleosome positioning and transcription factor binding, must play a significant role. Using a novel paired-end MNase digestion dataset, I'm attempting to identify chromatin signatures that are characteristic of replication origins. -
Postbaccalaureate IrtaNational Institutes Of Health Jun 2008 - Jul 2010Bethesda, Md, UsCasellas LabGenomics and Immunity/Laboratory of Molecular Immunology/NIAMSBasic science research in B cell genomics. -
Undergraduate ResearchCornell University Aug 2006 - May 2008Ithaca, Ny, UsRoberts LabMolecular Biology and GeneticsExplored the role of antiterminator proteins on E. coli transcription.
Jason Belsky Skills
Jason Belsky Education Details
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Duke UniversityComputational Biology And Bioinformatics -
Cornell UniversityBiological And Environmental Engineering
Frequently Asked Questions about Jason Belsky
What company does Jason Belsky work for?
Jason Belsky works for Ambry Genetics
What is Jason Belsky's role at the current company?
Jason Belsky's current role is Manager, Bioinformatics at Ambry Genetics.
What is Jason Belsky's email address?
Jason Belsky's email address is ja****@****gen.com
What is Jason Belsky's direct phone number?
Jason Belsky's direct phone number is +191426*****
What schools did Jason Belsky attend?
Jason Belsky attended Duke University, Cornell University.
What skills is Jason Belsky known for?
Jason Belsky has skills like Bioinformatics, Genomics, Molecular Biology, Genetics, Computational Biology, Data Analysis, R, Dna, Cell, Cell Biology, Dna Sequencing, Science.
Who are Jason Belsky's colleagues?
Jason Belsky's colleagues are Christina Alamillo, Ms, Cgc, Lgc, Colleen Velasco, Melissa Forant, Frankie Fann, Natalia Hernandez Morales, Marcus Mahar, Ph.d., Karina Guzman.
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